Júlia Beatriz Pereira Souza

INTERAÇÕES PLANTA MEDICINAL X MEDICAMENTO CONVENCIONAL NO TRATAMENTO DA HIPERTENSÃO ARTERIAL

Hypertension, among chronic diseases, appears as health problem with one of the greatest magnitude, at present is one of the main causes of cardiovascular morbidity and mortality in Brazil. The treatment consists in the use of synthetic drugs and medicinal plants, and this association is getting even more frequent, increasing the risks of interactions. This work is aimed to describe, through a literature review, the main interactions between herbal and synthetic drugs used in the therapy of hypertension and discuss the implications of these products concomitant use. A narrative literature review was carried out in papers published in the period 2006-2016 addressing drug interactions with medicinal plants from the ethnopharmacological survey, followed by studies of antihypertensive activity confirmation. The plants recognized for the hypertension treatment were Allium sativum, Alpinia zerumbet, Citrus sp., Lippia alba, Passiflora sp., Cymbopogon citratus, Sechium edule. Possible interactions of these plants with synthetic drugs to treat hypertension were evaluated. It was noted that the main interactions involved in the use of herbal associated with the use of medications are a pharmacodynamic type. Thus it is necessary to be cautious when associating the use of plants with synthetic drugs.

AVALIAÇÃO DA ROTULAGEM E PARÂMETROS DE QUALIDADE DE SABONETES ÍNTIMOS

Objective: Intimate soaps should protect the female genital area and thus allow for the maintenance of the natural microbiota therein. Here, we verified quality parameters of intimate soaps commercially available, including general physicochemical and microbiological characteristics based on specific requirements for this type of product. Material and Methods: A total of five brands of intimate soaps were analyzed. With regard to physicochemical aspects, tests measuring pH, viscosity and density, the centrifuge test and the lather index test were performed. The soups were also tested for their efficacy against Candida albicans clinical isolate with standardized density of approximately 0.5x10