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Julie Dixon

Bayer HealthCare Pharmaceuticals

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Featured researches published by Julie Dixon.

Expert Opinion on Therapeutic Patents | 2005

VEGF receptor kinase inhibitors: phthalazines, anthranilamides and related structures

Jacques Dumas; Julie Dixon

Inhibition of vascular endothelial growth factor receptor (VEGFR) signalling, using either antibodies or small molecule inhibitors of the VEGFR kinase domain, has become a major area of research in oncology. The phthalazine PTK787/ZK222584, first published in the literature in 1998, is one of the most advanced VEGFR inhibitors in the clinic. This paper provides an update on the patenting activity related to the phthalazine class. In addition, newer kinase inhibitor pharmacophores derived from this class (e.g., anthranilamides) will be reviewed.

Archive | 2002

2-phenylamino-4-(5-pyrazolylamino)-pyrimidine derivatives as kinase inhibitors, in particular, src kinase inhibitors

Julie Dixon; William J. Scott; Jacques Dumas; Catherine Brennan; Holia Hatoum-Mokdad

Archive | 2003

2-4-(di-phenyl-amino)-pyrimidine derivatives useful for treating hyper-proliferative disorders

Jill E. Wood; Donald Bierer; Brian Bear; Catherine Brennan; Brent Chandler; Gang Chen; Yuanwei Chen; Julie Dixon; Wenlang Fu; Leatte Guernon; Donglei Liu; Andrea Mcclure; Karl Miranda; Dhanapalan Nagarathnam; Robert Sibley; Michael Robert Turner; Sharad Verma; Chunguang Wang; Lin Yi; Jin Zhao; Qingming Zhu

Archive | 2006

Pyrrolo[2,1-f] [1,2,4] triazin-4-ylamines igf-1r kinase inhibitors for the treatment of cancer and other hyperproliferative diseases

Stephen J. O'connor; Jacques Dumas; Wendy Lee; Julie Dixon; David Cantin; David Gunn; Jennifer Burke; Barton Phillips; Derek Lowe; Tatiana Shelekhin; Gan Wang; Xin Ma; Shihong Ying; Andrea Mcclure; Furahi Achebe; Mario Lobell; Frederick J. Ehrgott; Christiana Iwuagwu; Kyle Parcella

Archive | 2002

2,4-diamino-pyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Jacques Dumas; Julie Dixon; Robert Sibley; Jill E. Wood

Archive | 2002

Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents

Jacques Dumas; Robert Sibley; Roger A. Smith; Ning Su; Yuanwei Chen; Jill E. Wood; Leatte Guernon; Julie Dixon; Catherine Brennan; Stephen Boyer

Archive | 2002

Avb3 and avb5 integrin antagonists and methods of treating diseases or conditions associated with avb3 and avb5 integrins

Julie Dixon; Catherine Brennan; Jacques Dumas; Holia Hatoum-Mokdad; Robert Sibley; Barry Hart; Uday Khire; William J. Scott; Jeffrey Johson; Peying Liu; Aniko Redman; Jill E. Wood

Archive | 2007

Derivados de 4-amino-pirrolotriazina sustituidos útiles para el tratamiento de trastornos hiperproliferativos y enfermedades asociadas con angiogénesis

Julie Dixon; Steven Magnuson; Barton Phillips; Yamin Wang; Tindy Li; Kyle Parcella; Jason Newcom; Harold C. E. Kluender; Zhenqiu Hong; Brent Chandler; Zhonghua Zhang; Kristen Allegue; Zheng Liu

Archive | 2006

Derivatives of 4-amino-pyrrolotriazine compounds useful for treating hyperproliferative disorders and diseases associated with angiogenesis

Julie Dixon; Steven Magnuson; Barton Phillips; Yamin Wang; Tindy Li; Kyle Parcella; Jason Newcom; Harold C. E. Kluender; Zhenqiu Hong; Brent Chandler; Zhonghua Zhang; Kristen Allegue; Zheng Liu

Archive | 2006

Zur behandlung von hyperproliferationserkrankungen und mit angiogenese assoziierten krankheiten geeignete substituierte 4-aminopyrrolotriazinderivate

Julie Dixon; Barton Phillips; Furahi Achebe; Harold C. E. Kluender; Jason Newcom; Kyle Parcella; Stephen J. O'connor; Steven Magnuson; Zhenqiu Hong; Zhonghua Zhang; Zheng Liu; Uday Khire; Lei Wang; Martin Michels; Brent Chandler

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