Julie Merrell

Positive response to binge eating intervention enhances postoperative weight loss

BACKGROUND Binge eating disorder has been suggested as a predictor of negative outcomes, including weight regain and poorer weight loss, particularly if the symptoms (e.g., loss of control eating) remain after surgery. Binge eating disorder has been viewed by some as a contraindication for weight loss surgery, and preoperative treatment has been recommended to help reduce binge eating behaviors. The objective of the present study was to evaluate whether the response to a preoperative binge eating intervention related to differential postoperative weight loss at an academic medical center. METHODS A total of 128 bariatric surgery candidates completed a brief cognitive behavioral group treatment for binge eating behaviors. The patients were categorized as positive responders or nonresponders according to the postintervention outcomes, including binge eating symptoms and episodes. The percentage of excess body weight loss (%EBWL) was measured at 6 and 12 months after surgery. RESULTS Across all bariatric procedures, the positive responders to the brief binge eating intervention had lost significantly more weight at 6 months (46% EBWL versus 38% EBWL) and 12 months (59% EBWL versus 50% EBWL) postoperatively. The results for a subsample of Roux-en-Y gastric bypass patients (n = 89) were also significant, with 53% EBWL for the responders and 42% EBWL for the nonresponders at 6 months and 68% EBWL versus 54% EBWL at 12 months postoperatively, respectively. CONCLUSION The response to binge eating treatment could be an important predictor of postoperative weight loss. The results from the present study provide support for patients who respond to preoperative binge eating treatment having enhanced surgical outcomes.

Assessing Psychosocial Functioning of Bariatric Surgery Candidates with the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF)

BackgroundPsychological comorbidity is common in bariatric surgery candidates. Many multidisciplinary teams incorporate psychometric testing to screen for psychological factors that, if left unattended, may negatively impact surgical results. Here, we report descriptive findings and empirical correlates of Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF) scales among of bariatric surgery candidates undergoing a pre-surgical psychological evaluation.MethodsThe sample consisted of male (n = 324) and female (n = 658) patients seeking bariatric surgery who were administered the MMPI-2-RF at their psychological evaluation. Psychosocial and medical variables were retrospectively coded from the patients’ medical records. These criteria included history/current mental health diagnoses and treatments, maladaptive eating behaviors/diagnoses, past/current substance use, abuse history, sleep apnea, and denial of surgery.ResultsDescriptive analyses demonstrated similar findings for male and female candidates and replicated previous reports. MMPI-2-RF scales measuring emotional dysfunction were associated with maladaptive eating patterns, a history of Major Depressive Disorder, and previous suicide attempts. Scale scores measuring behavioral dysfunction were associated with current/past substance use and previous physical abuse. MMPI-2-RF scale scores measuring somatic problems were associated with a higher BMI at the time of surgery, sleep apnea diagnosis/adherence, physical/sexual abuse history, active mood disorder, previous mental health diagnoses, and maladaptive eating patterns.ConclusionsThe MMPI-2-RF can aid in identifying a broad range of psychological comorbidity among bariatric surgery candidates. When used in conjunction with a pre-surgical psychological interview, it can aid in the assessment of psychological factors relevant to pre-surgical psychological assessment of bariatric surgery candidates.

Prevalence and psychosocial correlates of self-reported past suicide attempts among bariatric surgery candidates

BACKGROUND Although research has been limited, suicidal behavior has commonly been identified as a contraindication for bariatric surgery. The present study aimed to determine the prevalence and correlates of past suicide attempts in a bariatric surgery population at an academic medical center. METHODS A retrospective chart review, including the demographic and psychosocial variables, was conducted of 1020 consecutive bariatric surgery candidates presenting during a 32-month period. RESULTS Of the 1020 patients, 115 (11.2%) self-reported ≥ 1 previous suicide attempt. The patients with a positive suicide history were significantly younger (mean 42.9 ± 11.0 years), less educated (mean 13.4 ± 2.4 years), had a greater body mass index (mean 52.3 ± 11.6 kg/m(2)), and were more predominantly single (32.2% versus 20.9%), female (90.4% versus 74.8%), and receiving disability (45.2% versus 21.8%) compared with patients without a suicide history. A positive suicide history was also significantly associated with a history of psychiatric hospitalization, outpatient psychotherapy and/or psychotropic medication, sexual abuse, and substance abuse. CONCLUSION Assessing suicide history is an important aspect of the bariatric preoperative assessment. Additional research is needed to evaluate the effects of suicide history on the postoperative outcomes and adherence.

Psychological risk may influence drop-out prior to bariatric surgery.

BACKGROUND Factors necessitating a delay before psychological clearance for bariatric surgery have been previously identified; however, research has not examined why patients who begin the preoperative evaluation fail to complete surgery or drop-out of bariatric programs. This study sought to explore the potential psychosocial reasons for a failure to reach bariatric surgery. The setting was an academic medical center. METHODS Data were analyzed from 129 patients psychologically evaluated for bariatric surgery who had failed to reach surgery after 15 months. Medical records were reviewed for demographics, body mass index, and psychiatric variables. RESULTS The most common reasons for not reaching surgery included withdrawal from the program, outstanding program requirements, self-canceled surgery, moving out of the area, insurance denial, switching to non-surgical weight management, or death. Patients with outstanding program requirements were psychosocially different from patients who had not achieved surgery for other reasons. They were significantly more likely to be involved in outpatient behavioral health treatment (chi-square = 12.90, P < .05), to be taking psychotropic medications (chi-square = 15.17, P < .05), and to have met the criteria for current or past alcohol abuse/dependence (chi-square = 23.70, P < .01), and there was a trend for previous inpatient hospitalizations (chi-square = 11.59, P < .07). CONCLUSION Patients who failed to complete outstanding program requirements often had significant psychiatric and/or substance abuse/dependence issues that required additional treatment. It is possible that these patients drop-out of the program due to unwillingness to complete psychiatric treatment recommendations. Continued screening of high-risk patients and the education of patients on the importance of managing these risks is indicated. However, patients may choose to leave programs once education has been provided or treatment mandated.

Pilot evaluation of a substance abuse prevention group intervention for at-risk bariatric surgery candidates

BACKGROUND Concerns have been raised about an increased incidence of substance abuse after bariatric surgery. Alcohol use after surgery may be particularly problematic because of changes in pharmacokinetics leading to greater intoxication. The present study evaluated a substance abuse prevention group pilot intervention for at-risk bariatric surgery candidates. METHODS Patients with a history of substance abuse/dependence or at-risk substance use applying for weight loss surgery (WLS; N = 86) were referred to a single-session 90-minute intervention (67.4% female; 65.1% Caucasian; mean age 46.2 years; mean body mass index 48.77 kg/m(2)). The session included education about the health effects of alcohol/substances on WLS outcomes, developing alternative coping strategies, identifying warning signs of misuse, and providing treatment resources. Patients completed a preintervention and postintervention questionnaire measuring knowledge of substance use health effects, the Alcohol Use Disorders Identification Test-Consumption Items, and items on motivation for abstinence. RESULTS Patients reported a significant increase in knowledge regarding the negative effects of substance abuse after surgery (t = 42.34; P<.001). Patients also reported more healthy alternative coping strategies after the intervention (t = 18.96; P<.001). In addition, a significant number of patients reported a lower intention of consuming alcohol after surgery (χ(2) = 16.18; P<.001) and were more likely to report health reasons as motivation to abstain (χ(2) = 102.89; P< .001). CONCLUSIONS At-risk patients applying for weight loss surgery may benefit from a substance abuse prevention intervention. More research will be needed to see if such benefits can be sustained over time and if interventions affect postsurgical behaviors.

Use of the MMPI-2-RF Suicidal/Death Ideation and Substance Abuse Scales in Screening Bariatric Surgery Candidates

Bariatric surgery patients are at increased risk for suicide and lifetime substance abuse problems, and these risks are surgical contraindications. The Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) has scales to screen for these risks factors, among others. We seek to evaluate the classification accuracy of the MMPI-2-RF Suicidal/Death Ideation (SUI) and Substance Abuse (SUB) scales to optimize their use in bariatric surgery settings. Data were collected from 1,311 (72.1% female; 65.5% Caucasian) bariatric surgery candidates from the Cleveland Clinic as well as 295 (94.1% female; 85.9% Caucasian) bariatric surgery candidates from a private practice in St. Paul, Minnesota. Classification accuracies were calculated at original and revised SUI and SUB interpretative cutoffs in the Cleveland Clinic sample and replicated in the St. Paul sample. Significant and meaningful classification accuracy gains were demonstrated by excluding a death ideation item from the SUI scale and lowering the interpretive cutoff on the SUB scale. Practical implications and study limitations are discussed.

Older bariatric surgery candidates: is there greater psychological risk than for young and midlife candidates?

BACKGROUND Although severe obesity is dramatically increasing in older adults, many bariatric programs use age cutoffs due to concerns about greater perioperative morbidity and mortality risks. More recently, surgical outcomes have been reported in older adults. However, a paucity of data is available on the psychological risks of older bariatric candidates. Our objective is to examine psychiatric risk factors and weight loss outcomes in older (≥65 yr) versus midlife (40-55 yr) versus young adult (18-29 yr) patients. METHODS Older, midlife, and young adults (n = 608) who underwent weight loss surgery (74.6% women, 75.6% white, mean body mass index 48.07 ± 9.61 kg/m2) at the Cleveland Clinic Bariatric and Metabolic Institute completed a psychiatric diagnostic interview, and the Minnesota multiphasic personality inventory-2-restructured form, binge eating scale, and Cleveland Clinic behavioral rating scale before surgery. The data gathered from follow-up visits and weight loss outcomes at 1, 3, 6, 9, 12, and 18 months after surgery were measured. RESULTS Young adults had a greater reduction in excess body mass index than those at midlife in the first 6 months but no age differences were noted in the following year. Older patients were less likely to have a suicide history but the groups were equivalent on other psychiatric variables and self-report measures. Psychologist evaluators rated older adults less favorably on the capacity to consent and realistic nature of expectations. CONCLUSION Although medical risks may cause concern, older adults do not demonstrate any increased psychological risk factors compared with midlife or young adult surgical candidates and evidenced equivalent weight loss. However, concerns with lower ratings on consent and expectations warrant additional research.

Depression and infertility in women seeking bariatric surgery

BACKGROUND Obesity has been associated with abnormalities in reproductive functioning and fertility in women. A number of potential mechanisms have been identified, including neuroendocrine functioning and polycystic ovarian syndrome. Associations between infertility, depression, and anxiety have been found in nonobese populations; however, the relationship between depression and infertility in women pursuing bariatric surgery has not been examined. This study sought to explore potential psychosocial correlates of infertility in a female bariatric population. METHODS Data were analyzed from female patients of childbearing age (n = 88; 70.5% Caucasian; mean age 36.2; mean education 14.3 years; mean body mass index [BMI] 47.9 kg/m(2)) psychologically evaluated for bariatric surgery. Participants were dichotomized as Infertility+(n = 43) or Infertility-(n = 45) based on a medical history self-report questionnaire. Medical records were reviewed for demographic characteristics, BMI, physical and/or sexual abuse history, psychiatric medication usage, outpatient behavioral health treatment, and psychiatric diagnoses. RESULTS Women identified as Infertility+were more likely to have been diagnosed with a depressive disorder not otherwise specified or a major depressive disorder (χ(2) = 3.71, P<.05, χ(2) = 4.33, P< .05) than Infertility-women. However, Infertility+women were less likely to be involved in outpatient behavioral health treatment (χ(2) = 5.65, P< .05) or to have a history of psychotropic medication usage (χ(2) = 4.61, P<.05). CONCLUSION Women struggling with infertility may be more psychiatrically vulnerable than other bariatric surgery candidates and less likely to have received mental health treatment. Additional research on the association between fertility, depression, behavioral health treatment, and obesity is warranted. Future research should consider whether this potential relationship changes after bariatric surgery.