Jun Hui Park

Characterization and electrocatalytic properties of Prussian blue electrochemically deposited on nano-Au/PAMAM dendrimer-modified gold electrode

Gold electrode was modified with 3-mercaptopropionic acid (MPA) and further reacted with poly(amidoamine) (PAMAM) dendrimer (generation 4.0) then attached the nano-Au to obtain films on which Prussian blue (PB) was electrochemically deposited to afford much wider pH adaptive range, much better electrochemical stability and excellent electrochemical response. The microstructure and electrochemical behavior of Au/MPA/PAMAM/nano-Au/PB electrode were investigated by scanning electron microscopy (SEM) and cyclic voltammetry. The electrochemical response of the Au/MPA/PAMAM/nano-Au/PB-modified electrode for the electrocatalytic reduction of hydrogen peroxide was investigated, and it was found that the sensitivity as well as the corresponding detection limits were improved as compared to the voltammetric response of a Au/PB-modified electrode and Au/MPA/PAMAM/PB electrode. Based on this, a new electrochemical sensor for determination of hydrogen peroxide has been developed.

Label-Free Detection of Single Living Bacteria via Electrochemical Collision Event

We detected single living bacterial cells on ultramicroelectrode (UME) using a single-particle collision method and optical microscopic methods. The number of collision events involving the bacterial cells indicated in current-time (i-t) curves corresponds to the number of bacterial cells (i.e., Escherichia coli) on the UME surface, as observed visually. Simulations were performed to determine the theoretical current response (75 pA) and frequency (0.47 pM−1 s−1) of single Escherichia coli collisions. The experimental current response (83 pA) and frequency (0.26 pM−1 s−1) were on the same order of magnitude as the theoretical values. This single-particle collision approach facilitates detecting living bacteria and determining their concentration in solution and could be widely applied to studying other bacteria and biomolecules.

Nanosieving of anions and cavity-size-dependent association of cyclodextrins on a 1-adamantanethiol self-assembled monolayer.

In this paper, we studied charge transfer through a self-assembled monolayer (SAM) of 1-adamantanethiol on gold. Charge transfer through the 1-adamantanethiol SAM depended on the type of anion present when [Fe(CN)6]3- was used as a redox probe. The sluggish charge transfer process was monitored by cyclic voltammetry using the relatively large and hydrophobic perchlorate and hexafluorophosphate ions as the supporting electrolyte. In contrast, the charge transfer kinetics were nearly identical to those measured on bare gold with chloride, sulfate, and nitrate ions as the supporting electrolyte. We investigated the adsorption of alpha- and beta-cyclodextrin on the 1-adamantanethiol SAM via a host-guest interaction. The 1-adamantanethiol SAM could not bind beta-cyclodextrin via a host-guest interaction, probably due to the proximity of neighboring adamantine molecules on the surface. Immobilization of alpha-cyclodextrin by formation of an exterior complex with the SAM suppressed charge transfer. The adsorbed alpha-cyclodextrin was quantified using faradaic impedance experiments. The obtained adsorption isotherm was in good agreement with the Langmuir isotherm with a binding constant of 39.53 M(-1).

Ordered Polymeric Microhole Array Made by Selective Wetting and Applications for Electrochemical Microelectrode Array

In this paper, we report the microelectrode array fabrication using selective wetting/dewetting of polymers on a chemical pattern which is a simple and convenient method capable of creating negative polymeric replicas using polyethylene glycol (PEG) as a clean and nontoxic sacrificial layer. The fabricated hole-patterned polypropylene film on gold demonstrated enhanced electrochemical properties. The chemical pattern is fabricated by microcontact printing using octadecanethiol (ODT) as an ink on gold substrate. When PEG is spin-cast on the chemical pattern, PEG solution selectively dewets the ODT patterned areas and wets the remaining bare gold areas, leading to the formation of arrayed PEG dots. A negative replicas of the PEG dot array is obtained by spin-coating of polypropylene (PP) solution in hexane which preferentially interacts with the hydrophobic ODT region on the patterned gold surface. The arrayed PEG dots are not affected the during PP spin-coating step because of their intrinsic immiscibility. Consequently, the hole-patterned PP film is obtained after PEG removal. The electrochemical signal of the PP film demonstrates the negligible leakage current by high dielectric and self-healing of defects on the chemical pattern by the polymer. This method is applicable to fabrication of microelectrode arrays and possibly can be employed to fabricate a variety of functional polymeric structures, such as photomasks, arrays of biomolecules, cell arrays, and arrays of nanomaterials.

Programmable Electrochemical Rectifier Based on a Thin-Layer Cell

A programmable electrochemical rectifier based on thin-layer electrochemistry is described here. Both the rectification ratio and the response time of the device are programmable by controlling the gap distance of the thin-layer electrochemical cell, which is easily controlled using commercially available beads. One of the electrodes was modified using a ferrocene-terminated self-assembled monolayer to offer unidirectional charge transfers via soluble redox species. The thin-layer configuration provided enhanced mass transport, which was determined by the gap thickness. The device with the smallest gap thickness (∼4 μm) showed an unprecedented, high rectification ratio (up to 160) with a fast response time in a two-terminal configuration using conventional electronics.