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K Smithies

University College London

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Publication

Featured researches published by K Smithies.

Enzyme and Microbial Technology | 2007

Substrate spectrum of ω-transaminase from Chromobacterium violaceum DSM30191 and its potential for biocatalysis

U Kaulmann; K Smithies; Mark E. B. Smith; Helen C. Hailes; John M. Ward

Organic Process Research & Development | 2010

A Multidisciplinary Approach Toward the Rapid and Preparative-Scale Biocatalytic Synthesis of Chiral Amino Alcohols: A Concise Transketolase-/omega-Transaminase-Mediated Synthesis of (2S,3S)-2-Aminopentane-1,3-diol

Mark E. B. Smith; B.H. Chen; Edward G. Hibbert; U Kaulmann; K Smithies; James L. Galman; Frank Baganz; Helen C. Hailes; Gary J. Lye; John M. Ward; John M. Woodley; Martina Micheletti

Tetrahedron-asymmetry | 2009

Stereoselectivity of an ω-transaminase-mediated amination of 1,3-dihydroxy-1-phenylpropane-2-one

K Smithies; Mark E. B. Smith; U Kaulmann; James L. Galman; John M. Ward; Helen C. Hailes

European Journal of Organic Chemistry | 2006

The First Mimetic of the Transketolase Reaction

Mark E. B. Smith; K Smithies; Tarik Senussi; Helen C. Hailes

In: (Proceedings) European Protein Society. : Stockholm, Sweden. (2007) | 2007

Comparison of the natural and directed evolution of transketolase.

Edward G. Hibbert; Meb Smith; K Smithies; U Kaulmann; Helen C. Hailes; John M. Ward

In: (Proceedings) BioFine 2008. : Freiburg, Germany. (2008) | 2007

Accelerating biocatalytic process design: Integrating new tools from biology, chemistry and engineering.

Frank Baganz; B.H. Chen; Edward G. Hibbert; G.J. Lye; Martina Micheletti; John M. Woodley; U Kaulmann; John M. Ward; Helen C. Hailes; Meb Smith; K Smithies; 陈秉辉

International Symposium on the Chemistry of Natural Products | 2006

P-240 ENGINEERING AND DIRECTED EVOLUTION OF BIOCATALYTIC PATHWAYS TO AMINODIOLS IN BACTERIA

Mark E. B. Smith; K Smithies; Edward G. Hibbert; U Kaulmann; Martina Micheletti; B.H. Chen; Helen C. Hailes; John M. Ward; G.J. Lye; John M. Woodley

In: (Proceedings) Multistep Enzyme Catalysed Process,. : Austria. (2006) | 2006

Towards a two-step enzymatic system for chiral aminodiol formulation

U Kaulmann; K Smithies; Meb Smith; John M. Woodley; John M. Ward

In: (Proceedings) International symposium on Organocatalysis in Organic Synthesis. : Glasgow. (2006) | 2006

Combining organocatalysis and enzyme catalysis: Carbon-carbon bon formation followed by amination

K Smithies; U Kaulmann; Meb Smith; John M. Ward; John M. Woodley; Helen C. Hailes

In: (Proceedings) IUPAC International Conference of Biodiversity and Natural Products. : Kyoto, Japan. (2006) | 2006

Biocatalytic and organocatalytic approaches to ketodiols and aminodiols

Meb Smith; K Smithies; Edward G. Hibbert; U Kaulmann; Tarik Senussi; Sean J. Costelloe; Helen C. Hailes; John M. Ward; John M. Woodley

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Collaboration

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Helen C. Hailes

University College London

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John M. Ward

University College London

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U Kaulmann

University College London

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John M. Woodley

Technical University of Denmark

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Edward G. Hibbert

University College London

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Mark E. B. Smith

University College London

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Tarik Senussi

University College London

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B.H. Chen

University College London

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Martina Micheletti

University College London

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Frank Baganz

University College London

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