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Dive into the research topics where K. Sutoh is active.

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Featured researches published by K. Sutoh.


Biochemical Society Transactions | 2008

Molecular mechanism of force generation by dynein, a molecular motor belonging to the AAA+ family

Naoki Numata; Takahide Kon; Tomohiro Shima; Kenji Imamula; Toshifumi Mogami; Reiko Ohkura; K. Sutoh; Kazuo Sutoh

Dynein is an AAA+ (ATPase associated with various cellular activities)-type motor complex that utilizes ATP hydrolysis to actively drive microtubule sliding. The dynein heavy chain (molecular mass >500 kDa) contains six tandemly linked AAA+ modules and exhibits full motor activities. Detailed molecular dissection of this motor with unique architecture was hampered by the lack of an expression system for the recombinant heavy chain, as a result of its large size. However, the recent success of recombinant protein expression with full motor activities has provided a method for advances in structure-function studies in order to elucidate the molecular mechanism of force generation.


Biochemical and Biophysical Research Communications | 1998

A Novel Dictyostelium discoideum Gene Required for cAMP-Dependent Cell Aggregation

Akira Nagasaki; K. Sutoh; Hiroyuki Adachi; Kazuo Sutoh


Biophysical Journal | 2009

Elucidation Of Structural States Of Dimeric Motor Domain Of Dynein Using Cys-light Construct

Yuya Hasegawa; Tomohiro Shima; Takahide Kon; K. Sutoh; Kazuo Sutoh


生物物理 | 2008

1P-150 Cys-lightダイニンを用いたダイニン機能の分子メカニズムの解明(分子モーター(1),第46回日本生物物理学会年会)

Yuya Hasegawa; K. Sutoh; Reiko Ohkura; Takahide Kon; Kazuo Sutoh


Seibutsu Butsuri | 2008

1P-150 Elucidation of the molecular mechanism of dynein function using Cys-light cytoplasmic dynein(The 46th Annual Meeting of the Biophysical Society of Japan)

Yuya Hasegawa; K. Sutoh; Reiko Ohkura; Takahide Kon; Kazuo Sutoh


Seibutsu Butsuri | 2007

3P141 Construction of Cys-light cytoplasmic dynein(Molecular motors,Poster Presentations)

Yuya Hasegawa; K. Sutoh; Reiko Ohkura; Takahide Kon; Kazuo Sutoh


Seibutsu Butsuri | 2005

1P161 Interaction between the tail and the AAA ring structure of cytoplasmic dynein

Naoki Numata; Takahide Kon; Reiko Ohkura; K. Sutoh


Seibutsu Butsuri | 2005

3P193 Structural changes responsible for the dynein power stroke

Tomohiro Shima; K. Imamura; Takahide Kon; Reiko Ohkura; K. Sutoh


Seibutsu Butsuri | 2005

3P192 Three-dimensional Structure of cytoplasmic dynein by electron cryomicroscopy

Takuo Yasunaga; R. Saitoh; Takahide Kon; Masaya Nishiura; K. Sutoh


Seibutsu Butsuri | 2005

1P162 Kinetic analysis of the conformational changes of cytoplasmic dynein

Toshifumi Mogami; Takahide Kon; Reiko Ohkura; K. Sutoh

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