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Biochemical and Biophysical Research Communications | 1987

Dopamine binding to the alpha receptor in pregnant rabbit myometrium

Mark Phillippe; Vanessa A. Barss; K.V. Jackson; Lawrence Valles; George Giannopoulos

This study evaluated in vitro binding of dopamine ligands to myometrial alpha adrenoceptors. With cell membranes from pregnant rabbits, receptor radioligand binding studies utilizing [3H] dihydroergocryptine +/- dopamine demonstrated receptor affinity (KD) = 0.75 +/- 0.10 nM (+/- SEM) and density (Bmax) = 533.2 +/- 45.2 fM/mg protein. Similar studies utilizing phentolamine or apomorphine gave essentially identical results. Competition binding studies demonstrated steriospecific butaclamol binding, along with significant binding of haloperidol, spiperone, apomorphine, and bromoergocryptine. These observations provide a mechanism for the observed uterotonic effects of dopamine.


Fertility and Sterility | 2008

Are survival and implantation potential of cryopreserved zygotes affected by time of freezing and duration of storage

T.S. Ceyhan; K.V. Jackson; Stacey A. Missmer; Aida Nureddin; Catherine Racowsky


Fertility and Sterility | 2008

Is day 3 follicle stimulating hormone level an essential determinant for deciding whether to initiate in vitro fertilization cycles in older patients

T.S. Ceyhan; S. Kilic; K.V. Jackson; Antonio R. Gargiulo; Catherine Racowsky


Fertility and Sterility | 2008

Increased endometrial thickness at baseline is associated with decreased success in in-vitro fertilization

R.S. Weinerman; Stacey A. Missmer; T.S. Ceyhan; Elena H. Yanushpolsky; K.V. Jackson; Catherine Racowsky


Fertility and Sterility | 2006

O-174 : Single embryo transfer on day 3: Optimizing patient selection and pregnancy outcome

Catherine Racowsky; K.V. Jackson; Christine C. Skiadas; Elizabeth S. Ginsburg


Fertility and Sterility | 2005

Should Extended Culture Be Performed in High Response Gonadotropin Intrauterine Insemination Cycles That Are Converted To In Vitro Fertilization

Sunny H. Jun; K.V. Jackson; Janis H. Fox; Catherine Racowsky


Fertility and Sterility | 2005

HMG Increases the Yield of Mature Oocytes and Excellent Quality Embryos in Patients With a History of High Incidence of Oocyte Immaturity

H.G. Huddleston; K.V. Jackson; Catherine Racowsky


Fertility and Sterility | 2005

Is Early Compaction on Day 3 Associated With Increased Implantation Potential

Christine C. Skiadas; K.V. Jackson; Catherine Racowsky


Fertility and Sterility | 2004

Early pregnancy loss in multiple pregnancies after IVF

K. Bendikson; K.V. Jackson; N. Cabrera; Elizabeth S. Ginsburg


Fertility and Sterility | 2004

Variables that impact the use of cleavage rates in quality assurance assessment

S.L. Benedict; K.V. Jackson; K. Kelleher; Yuying Pan; Aida Nureddin; Catherine Racowsky

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