K. V. Sujith

4-Chloro-N′-[(Z)-4-(dimethyl­amino)benzyl­idene]benzohydrazide mono­hydrate

In the title compound, C16H16ClN3O·H2O, the dihedral angle between the two aromatic rings is 44.58 (11)°. The N atom of the dimethylamino group adopts a pyramidal configuration. In the crystal structure, molecules are linked into a two-dimensional network parallel to the (001) plane by intermolecular N—H⋯O, O—H⋯N and O—H⋯O hydrogen bonds involving the water molecule and C—H⋯Cl hydrogen bonds. In addition, C—H⋯π interactions are observed.

N′-[(E)-1-Phenyl­ethyl­idene]benzo­hydrazide

The title compound, C15H14N2O, crystallized with two independent molecules in the asymmetric unit. Both molecules are non-planar and have an E configuration with respect to the C=N bond. The dihedral angles between the two benzene rings are 11.1 (2)° in one molecule and 12.40 (19)° in the other. In the crystal structure, the molecules are linked by N—H⋯O hydrogen bonds and weak C—H⋯O interactions into infinite one-dimensional chains along [1 0 0]. The crystal structure is further stabilized by N—H⋯O hydrogen bonds, weak C—H⋯O and very weak C—H⋯π interactions.

4-(4-Bromo­benzyl­ideneamino)-1-(diphenyl­amino­meth­yl)-3-[1-(4-isobutyl­phen­yl)eth­yl]-1H-1,2,4-triazole-5(4H)-thione

In the title compound, C34H34BrN5S, the two phenyl rings of the diphenylaminomethyl group are inclined at an angle of 73.86 (8)° and they form dihedral angles of 74.04 (8) and 48.74 (8)° with the triazole ring. Intramolecular C—H⋯S hydrogen bonds generate S(6) and S(5) ring motifs. The crystal structure is stabilized by weak C—H⋯π interactions.

N′-[(Z)-4-(Dimethyl­amino)benzyl­idene]-4-nitro­benzohydrazide mono­hydrate

In the asymmetric unit of the title compound, C16H16N4O3·H2O, there are two symmetry-independent hydrazide molecules with almost identical geometries, and two independent water molecules. The dihedral angles between the two benzene rings in the two hydrazide molecules are 0.11 (5) and 0.77 (5)°. In one molecule, an intramolecular C—H⋯O hydrogen bond generates a ring of graph-set motif S(5). Intermolecular N—H⋯O, O—H⋯O, O—H⋯N and C—H⋯O hydrogen bonds and π–π stacking interactions between the benzene rings [centroid–centroid distances in the range 3.5021 (6)–3.6403 (6) Å] are observed, together with O⋯O [2.7226 (11) Å], O⋯N [2.7072 (10) Å] and N⋯O [2.7072 (10)–2.8582 (12) Å] short contacts. The hydrazine molecules are stacked along the b axis and adjacent molecules are linked by water molecules.

3-{1-[4-(2-Methyl-prop-yl)phen-yl]eth-yl}-1-(morpholinometh-yl)-4-(4-nitro-benzyl-ideneamino)-1H-1,2,4-triazole-5(4H)-thione.

The title ibuprofen-containing Mannich derivative, C26H32N6O3S, crystallizes with two independent molecules in the asymmetric unit. The morpholine ring in each molecule adopts a chair conformation. The 1,2,4-triazole ring forms dihedral angles of 2.13 (10) and 75.52 (10)° with the two substituted benzene rings in one molecule, with corresponding values of 19.36 (11)° and 89.03 (10)° in the other. The nitro groups are twisted from the attached benzene ring in each molecule. In the crystal packing, molecules are linked into supramolecular chains via weak C—H⋯O, C—H⋯N and C—H⋯S interactions, and C—H⋯π and N—O⋯π links also occur.

3-[1-(4-Isobutyl-phen-yl)eth-yl]-6-(4-methyl-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.

In the title compound, C22H24N4S, the methylphenyl and isobutylphenyl rings are inclined at an angle of 79.98 (1)° and they form dihedral angles of 4.59 (1) and 75.47 (1)°, respectively, with the triazolothiadiazole unit. An intramolecular C—H⋯S hydrogen bond generates an S(5) ring motif. The crystal structure is stabilized by intermolecular C—H⋯N hydrogen bonds and weak C—H⋯π and π–π interactions [centroid–centroid distances between the thiadiazole ring and a symmetry-related phenyl ring and between the triazole ring and the phenyl ring range from 3.5680 (8) to 3.7313 (8) Å].

4-[(E)-4-Bromo-benzyl-ideneamino]-3-methyl-1H-1,2,4-triazole-5(4H)-thione.

In the title molecule, C10H9BrN4S, the dihedral angle between the triazole and benzene rings is 12.32 (19)°. An intramolecular C—H⋯S hydrogen bond generates an S(6) ring motif. In the crystal packing, centrosymmetrically related molecules are linked into a dimer by N—H⋯S hydrogen bonds, and the dimers are linked into a chain running along [11] by Br⋯N short contacts [3.187 (3) Å]. The crystal packing is further strengthened by π–π interactions involving the triazole ring [centroid–centroid distance = 3.322 (2) Å].

2-[4-(2-Methyl­prop­yl)phen­yl]-N′-[(E)-1-phenyl­ethyl­idene]propane­hydrazide

In the title compound, C21H26N2O, the dihedral angle between the two aromatic rings is 85.90 (19)°. The propenone–hydrazide unit forms dihedral angles of 21.62 (8) and 72.83 (9)°, respectively, with the terminal and central aromatic rings. The 2-methylpropyl group is disordered over two sites, with occupancies of 0.533 (13) and 0.467 (13). In crystal structure, molecules are linked into centrosymmetric dimers by paired N—H⋯O and C—H⋯O hydrogen bonds. In addition, C—H⋯π interactions are observed.

2-(4-Isobutyl­phen­yl)-N′-[1-(4-nitro­phen­yl)ethyl­idene]propanohydrazide

The molecule of the title compound, C21H25N3O3, exists in a trans configuration with respect to the ethylidene unit. The dihedral angle between the two substituted benzene rings is 86.99 (7)°. The nitro group is twisted from the attached benzene ring at an angle of 17.02 (7)°. In the crystal structure, molecules are linked by pairs of N—H⋯O hydrogen bonds in a face-to-face manner into centrosymmetric dimers. These dimer units are further linked into chains along the c axis by weak C—H⋯O interactions. These chains are stacked along the b axis. The crystal is further stabilized by weak C—H⋯π interactions.

4-Amino-3-{1-[4-(2-methyl­prop­yl)phen­yl]eth­yl}-1H-1,2,4-triazole-5(4H)-thione

In the title triazole compound, C14H20N4S, the dihedral angle between the triazole and benzene rings is 83.29 (11)°. The methine H atom and two methyl groups of the isobutyl group are disordered over two sites with occupancies of 0.684 (9) and 0.316 (9). In the crystal structure, N—H⋯S hydrogen bonds link the molecules into chains running along the b axis. These chains are cross-linked into a two-dimensional network parallel to the ab plane by C—H⋯S hydrogen bonds.