Kadhim Sulaiman
Hamad Medical Corporation
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Publication
Featured researches published by Kadhim Sulaiman.
American Journal of Cardiology | 2009
Ayman El-Menyar; Mohammad Zubaid; Wafa Rashed; Wael Almahmeed; Jawad Al-Lawati; Kadhim Sulaiman; Ahmed Al-Motarreb; Haitham Amin; Rajvir Singh; Jassim Al Suwaidi
The aim of this study was to evaluate the gender differences in baseline characteristics, therapy, and outcomes in patients with acute coronary syndromes in 6 Middle Eastern countries. Over a 6-month period in 2007, 8,169 consecutive patients (74% men, 24% women) presenting with acute coronary syndromes were enrolled in a prospective, multicenter study from 6 adjacent Middle Eastern countries. Women were 9 years older than men and more likely to have diabetes, hypertension, and dyslipidemia. Women were more likely to present with unstable angina and more often had atypical presentations of ST elevation myocardial infarction. Compared to men, women were significantly less treated with beta blockers and antiplatelet therapy, whereas reperfusion therapy was nonsignificantly less used in women. In all patients with acute coronary syndromes, women not only ranked higher on Global Registry of Acute Coronary Events risk score but also had increased in-hospital mortality, 1.75 times that of men. This mortality difference persisted after adjusting for all confounders (odds ratios 1.76, 95% confidence interval 1.1 to 2.8, p <0.01). In conclusion, in addition to presentation with higher risk factors, female gender also independently predicted poorer outcomes in patients with ST elevation myocardial infarction.
Acta Cardiologica | 2009
Mohammad Zubaid; Wafa Rashed; Wael Almahmeed; Jawad Al-Lawati; Kadhim Sulaiman; Ahmed Al-Motarreb; Haitham Amin; Jassim Al Suwaidi; Khalid F. AlHabib
Objectives — To identify the characteristics, management and hospital outcomes of acute coronary syndrome (ACS) patients in the Gulf region of the Middle East. Methods and results — Overall, 8176 consecutive patients with the final diagnosis of ACS were recruited in 6 months, from 64 hospitals in 6 countries.The mean age of patients was 56 years. At presentation, 40% of patients had diabetes and 38% were current smokers. Of 2268 patients eligible for reperfusion, 183 (8%) underwent primary percutaneous coronary intervention, 1856 (82%) received thrombolytic therapy and 219 patients (10%) did not receive any reperfusion.The median door-to-needle time was 45 minutes.The majority of patients received aspirin (96%), beta-blockers (77%), angiotensin-converting enzyme inhibitors (77%) and statins (83%) at discharge. Less than 1 in 5 patients received coronary angiography (19%). Low-risk patients were more likely to undergo coronary angiography than high-risk patients (odds ratio 1.35, 95% confidence interval 1.15 to 1.58, P < 0.001). Patients with recurrent ischaemia were 4 times more likely to undergo coronary angiography than those without;and patients who lived in UAE and Bahrain were about 3-4 times more likely to undergo this procedure than those who lived in other participating countries (P < 0.001 for both).The overall hospital mortality was 3.6%. Conclusions — Patients with ACS in the Arab Middle East are younger than in developed countries and have higher rates of diabetes and smoking. There is good adherence to evidence-based medications; however, improvement in door-to-needle time and utilisation of interventional procedures is needed.
Circulation | 2011
Waleed M. Ali; K.F. Al Habib; Ahmed Al-Motarreb; Rajvir Singh; Ahmad Hersi; Hussam Al Faleh; Nidal Asaad; Shukri Al Saif; Wael Almahmeed; Kadhim Sulaiman; Haitham Amin; Jawad Al-Lawati; Nizar Al Bustani; Norah Q. Al-Sagheer; Awad Al-Qahtani; Jassim Al Suwaidi
Background— The khat plant is a stimulant similar to amphetamine and is thought to induce coronary artery spasm. Khat is widely chewed by individuals originating from the Horn of Africa and the Arabian Peninsula. The aim of this study was to evaluate the clinical characteristics and outcome of khat chewers presenting with acute coronary syndrome. Methods and Results— From October 1, 2008, through June, 30, 2009, 7399 consecutive patients with acute coronary syndrome were enrolled in the Second Gulf Registry of Acute Coronary Events (Gulf RACE-2). Nineteen percent of patients were khat chewers; 81% were not. Khat chewers were older, more often male, and less likely to have cardiovascular risk factors. Khat chewers were less likely to have a history of coronary artery disease and more likely to present late and to have higher heart rate and advanced Killip class on admission. Khat chewers were more likely to present with ST-segment–elevation myocardial infarction. Overall, khat chewers had higher risk of death, recurrent myocardial ischemia, cardiogenic shock, ventricular arrhythmia, and stroke compared with non–khat chewers. After adjustment for baseline variability, khat chewing was found to be an independent risk factor of death and for recurrent ischemia, heart failure, and stroke. Conclusions— Our data confirm earlier observations of worse in-hospital outcome among acute coronary syndrome patients who chew khat. This worse outcome persists up to 1 year from the index event. This observational report underscores the importance of improving education concerning the cardiovascular risks of khat chewing.
European Journal of Heart Failure | 2015
Kadhim Sulaiman; Prashanth Panduranga; Ibrahim Al-Zakwani; Alawi A. Alsheikh-Ali; Khalid F. AlHabib; Jassim Al-Suwaidi; Wael Almahmeed; Hussam AlFaleh; Abdelfatah Elasfar; Ahmed Al-Motarreb; Mustafa Ridha; Bassam Bulbanat; Mohammed Al-Jarallah; Nooshin Bazargani; Nidal Asaad; Haitham Amin
The purpose of this study was to describe the clinical characteristics, management, and outcomes of acute heart failure (HF) patients from the Gulf acute heart failure registry (Gulf CARE).
Circulation-cardiovascular Quality and Outcomes | 2011
Mohammad Zubaid; Wafa Rashed; Alawi A. Alsheikh-Ali; Wael Almahmeed; Abdullah Shehab; Kadhim Sulaiman; Ibrahim Al-Zakwani; Ahmed AlQudaimi; Nidal Asaad; Haitham Amin
Background—Atrial fibrillation (AF) is the most common serious cardiac arrhythmia, and its prevalence is expected to increase. There is lack of data about patient characteristics, practice patterns, and outcomes of AF in the Arab Middle East. Methods and Results—The Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) is a prospective, observational registry of patients with AF with a 12-month follow-up. The registry was emergency room based. Between October 2009 and June 2010, 2043 consecutive patients with AF were enrolled from 23 hospitals in 6 Middle Eastern Gulf countries. Data were collected on a standardized case report form and entered online. Data collected included patient demographics, medical history, type of AF, treatment, and outcome of emergency room visit. If patients were admitted, details of their treatment, investigations, and outcomes during hospital stay were collected. Completion of 12-month follow-up is expected by July 2011. The mean age was 57 years, and 52% were men. The most common concomitant condition was hypertension, present in 1072 (52%) patients. At enrollment, 28% of patients had a history of coronary artery disease, 30% had diabetes, and 16% had rheumatic valve disease. History of stroke and transient ischemic attacks were reported in 9% and 4% of patients, respectively. The most common type of AF, first attack AF, occurred in 37%, whereas 19% of patients had lone AF. Conclusions—Gulf SAFE will provide valuable insights into AF management and outcomes in the Gulf region of the Middle East.
Journal of Cardiology | 2011
Ayman El-Menyar; Mohammad Zubaid; Kadhim Sulaiman; Wael Almahmeed; Rajvir Singh; Alawi A. Alsheikh-Ali; Jassim Al Suwaidi
BACKGROUND Patients with acute coronary syndrome (ACS) frequently present with typical chest pain; however a considerable proportion may present with atypical symptoms. OBJECTIVE The purpose of this study was to evaluate the prognostic value of different presenting symptoms in ACS patients. METHODS Over a 5-month period in 2007, 6704 consecutive patients presenting with ACS were enrolled and categorized into three groups according to their presenting symptom (typical chest pain, atypical chest pain, and dyspnea). Data were collected from a prospective, multicenter, multinational, observational study from 6 countries. The baseline characteristics, therapy, and in-hospital outcomes were analyzed and compared in the three groups. RESULTS In comparison to typical chest pain, patients with atypical pain or dyspnea were older and had more cardiovascular risk factors. These two groups were significantly less likely to receive evidence-based therapy and coronary angiography and suffered worse in-hospital outcomes. The mortality rates were 3%, 2.5%, and 6% in patients presenting with typical, atypical chest pain, and dyspnea, respectively. After adjustment for confounders, the absence of typical chest pain was associated with higher mortality rate (odds ratio 2.0, 95% confidence intervals 1.29-2.75). CONCLUSIONS Across ACS, patients presenting without chest pain were frequently underestimated, less well treated with evidence-based therapy, and had worse in-hospital outcomes. Clinical presentation of ACS may provide additional prognostic impact particularly in high-risk populations.
PLOS ONE | 2013
Abdulla Shehab; Bayan Al-Dabbagh; Khalid F. AlHabib; Alawi A. Alsheikh-Ali; Wael Almahmeed; Kadhim Sulaiman; Ahmed Al-Motarreb; Nicolaas Nagelkerke; Jassim Al Suwaidi; Ahmad Hersi; Hussam Al Faleh; Nidal Asaad; Shukri Al Saif; Haitham Amin
Background Gender-related differences in mortality of acute coronary syndrome (ACS) have been reported. The extent and causes of these differences in the Middle-East are poorly understood. We studied to what extent difference in outcome, specifically 1-year mortality are attributable to demographic, baseline clinical differences at presentation, and management differences between female and male patients. Methodology/Principal Findings Baseline characteristics, treatment patterns, and 1-year mortality of 7390 ACS patients in 65 hospitals in 6 Arabian Gulf countries were evaluated during 2008–2009, as part of the 2nd Gulf Registry of Acute Coronary Events (Gulf RACE-2). Women were older (61.3±11.8 vs. 55.6±12.4; P<0.001), more overweight (BMI: 28.1±6.6 vs. 26.7±5.1; P<0.001), and more likely to have a history of hypertension, hyperlipidemia or diabetes. Fewer women than men received angiotensin-converting enzyme inhibitors (ACE), aspirin, clopidogrel, beta blockers or statins at discharge. They also underwent fewer invasive procedures including angiography (27.0% vs. 34.0%; P<0.001), percutaneous coronary intervention (PCI) (10.5% vs. 15.6%; P<0.001) and reperfusion therapy (6.9% vs. 20.2%; P<0.001) than men. Women were at higher unadjusted risk for in-hospital death (6.8% vs. 4.0%, P<0.001) and heart failure (HF) (18% vs. 11.8%, P<0.001). Both 1-month and 1-year mortality rates were higher in women than men (11% vs. 7.4% and 17.3% vs. 11.4%, respectively, P<0.001). Both baseline and management differences contributed to a worse outcome in women. Together these variables explained almost all mortality disparities. Conclusions/Significance Differences between genders in mortality appeared to be largely explained by differences in prognostic variables and management patterns. However, the origin of the latter differences need further study.
European Journal of Heart Failure | 2009
Alawi A. Alsheikh-Ali; Mouaz Al-Mallah; Wael Almahmeed; Nazar Albustani; Jassim Al Suwaidi; Kadhim Sulaiman; Mohammad Zubaid
We describe the prevalence and prognostic significance of heart failure (HF) complicating acute coronary syndromes (ACS) in patients enrolled in the Gulf Registry of Acute Coronary Events (Gulf RACE).
Heart Views | 2011
Mohammed Al-Mukhaini; Prashanth Panduranga; Kadhim Sulaiman; Abdulla Amour Riyami; Mohammed Deeb; Mohamed B. Al Riyami
Coronary perforation is a rare complication of percutaneous coronary intervention. We present two different types of coronary intervention, but both ending with coronary perforation. However, these perforations were tackled successfully by covered stents. This article reviews the incidence, causes, presentation, and management of coronary perforation in the present era of aggressive interventional cardiology. Coronary perforations are classified as type I (extraluminal crater), II (myocardial or pericardial blushing), and III (contrast streaming or cavity spilling). Types I and II coronary perforations are caused by stiff or hydrophilic guidewires. Type I has a benign prognosis, whereas type II coronary perforations have the potential to progress to tamponade. Type III coronary perforations are caused by balloons, stents, or other intracoronary devices and commonly lead to cardiac tamponade necessitating pericardial drainage. However, type III perforations can be managed with covered stents without need for surgical intervention.
European Journal of Preventive Cardiology | 2012
Jassim Al Suwaidi; Mohammad Zubaid; Ayman El-Menyar; Rajivir Singh; Nidal Asaad; Kadhim Sulaiman; Wael Al Mahmeed; Sulaiman Z. Al-Shereiqi; Moosa Akbar; Hajar A Al Binali
Objective: We evaluated the prevalence and effect of cigarette smoking (CS) and waterpipe (WP) smoking on patients with acute coronary syndrome (ACS) in six Middle-Eastern countries. Methods: Analysis of the Gulf Registry of Acute Coronary Events (Gulf RACE) survey, which included 6704 consecutive patients hospitalized with ACS, was made and patients were divided into four groups depending on whether they were smokers – cigarette-CS, waterpipe-WS, combined cigarette and waterpipe (CW) – or non-smokers (NS). Results: Overall 38% of patients were smokers; 4.4% of patients were waterpipe smokers (1.4% WS and 3% CW). When compared to the three smokers’ groups, non-smokers were older. Overall, smokers had fewer cardiovascular risk factors when compared to NS. ST-segment elevation myocardial infarction was more common among nicotine smokers (CS 54.4%, WS 57.3%, 47.3% CW vs 30% NS, p = 0.001) while NS were more likely to have non-ST elevation ACS. Cigarette (and not waterpipe) smokers were more likely to present early and with typical symptoms when compared to NS and WS. Admission heart rate and blood pressures were higher in the non-smoker group and WS. Non-smokers and WS were also more likely to present with Killip class >1. After adjustment for baseline variables, smoking was not an independent predictor of adverse cardiac events. Conclusion: Cigarette smoking is prevalent among Middle-Eastern patients presenting with acute coronary syndrome. Waterpipe smoking use is low; however it is relatively more frequent in women when compared to cigarette smoking. The current study underscores the need for further studies into the effects of different forms of nicotine smoking.