Kağan Gürkan
Ankara University
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Featured researches published by Kağan Gürkan.
Journal of Psychopharmacology | 2010
Kağan Gürkan; Ayhan Bilgiç; Serhat Türkoğlu; Birim Günay Kılıç; Ayla Aysev; Runa Uslu
The current study was designed to investigate the changes that occur in depression, anxiety, obsessive—compulsive symptoms and health-related quality of life during methylphenidate (MPH) treatment in children with attention-deficit hyperactivity disorder (ADHD). Forty-five treatment naive children with ADHD, aged 8—14, were assessed based on self, parent and teacher reports at the baseline and at the end of the first and third month of MPH treatment regarding changes in inattention, hyperactivity, impulsivity, depression, anxiety and obsessive—compulsive symptoms. Changes in the quality of life were also noted. Repeated measures of analysis of variance (ANOVA) tests with Bonferroni corrections were conducted in order to evaluate the data. Symptoms of inattention, hyperactivity and impulsivity were significantly reduced (p < 0.017) following a three-month MPH treatment. There were significant decreases in depression (p = 0.004), trait anxiety (p = 0.000) and checking compulsion symptom scores (p = 0.001). Moreover, parents reported significant improvements in psychosocial (p = 0.001) and total scores (p = 0.009) of quality of life, despite no change in physical health scores (p > 0.05). Children’s ratings of quality of life measures showed no significant changes in physical health and psychosocial scores (p > 0.05), while total scores significantly improved (p = 0.001) after the treatment. Over a three-month MPH treatment, depression, trait anxiety and checking compulsion symptoms decreased and quality of life seemed to improve along with those of inattention, hyperactivity and impulsivity.
The Journal of Urology | 2011
Berk Burgu; Ozgu Aydogdu; Kağan Gürkan; Runa Uslu; Tarkan Soygür
PURPOSE We investigated whether certain voiding problems have a higher incidence in patients with attention deficit disorder with hyperactivity compared to age matched controls. MATERIALS AND METHODS We used the Conners Parent Rating Scale-revised for attention deficit disorder with hyperactivity and lower urinary tract symptom score to evaluate voiding problems. A total of 62 children with attention deficit disorder and 124 healthy controls were enrolled. We evaluated uroflowmetry patterns in both groups. Residual urine volumes and Bristol stool scale were noted. We examined the correlation between total Conners Parent Rating Scale-revised and lower urinary tract symptom score in patients with attention deficit disorder. Additionally we analyzed each index of the Conners Parent Rating Scale-revised separately in terms of correlation with symptom subgroups for lower urinary tract symptom scores. RESULTS Mean ± SD total lower urinary tract symptom score was 11.1 ± 2.9 in patients with attention deficit disorder with hyperactivity and 3.2 ± 1.3 in controls, a difference that was statistically significantly (p <0.001). With the exception of constipation, mean scores of all lower urinary tract symptom subindices were significantly higher in patients with attention deficit disorder compared to controls. Symptoms evaluated in lower urinary tract symptom score were mostly correlated with attention deficit disorder index of the Conners Parent Rating Scale-revised. If a child with attention deficit disorder has a high index in the Conners Parent Rating Scale-revised, he or she is more likely to have urgency. Also, if a child with attention deficit disorder has a high hyperactivity subscale score, he or she is more likely to have enuresis. CONCLUSIONS Voiding problems are more common in children with attention deficit disorder with hyperactivity than in age matched controls. Urgency and enuresis are the outstanding problems in children with attention deficit disorder. Simultaneous use of the Conners Parent Rating Scale-revised and lower urinary tract symptom score questionnaire should be encouraged in patients with attention deficit disorder to allow a structured and quantitative evaluation of these overlapping problems.
World Journal of Biological Psychiatry | 2004
Nahit Motavalli Mukaddes; Osman Abali; Kağan Gürkan
Summary Recently, atypical antipsychotic treatments have been used in children with autistic disorder (AD). However, data on safety and efficacy of atypical antipsychotic agents in autistic children are limited. In this open, prospective trial, subjects were treated with risperidone for six weeks. Nineteen children (12 male, 7 female) aged 4 to 8 years were started on 0.5 mg daily with individual titration to a maximum of 1.5 mg daily. Behavioural assessments were completed by Conners parent 10-item index, AD symptom checklist and CGI-Global improvement. Statistically significant improvement was observed in mean total scores of Conners parent 10-item index from baseline to the end of study (p > 0.001). On the basis of the CGI-Global improvement item, 15 children were considered responders. Statistically significant improvement was also found in some aspects of social contact, impulsive-aggression and repetitive, ritualistic behaviour based on assessment with the AD-symptom checklist. Weight gain and increase in night-time sleep were the most frequent side effects.
Psychiatry and Clinical Neurosciences | 2006
Osman Abali; Hasan Nazik; Kağan Gürkan; Emin Ünüvar; Müjgan Sıdal; Betigül Öngen; Fatma Oguz; Ümran Tüzün
Abstract The purpose of the present study was to evaluate obsessive‐compulsive disease (OCD) in Turkish Children who had group A beta hemolytic streptococcal (GABHS) infections and those who had not. Thirty‐one children and adolescents (the study group) were compared with 28 children and adolescents. The Childrens Yale‐Brown Obsessive‐Compulsive Scale (CY‐BOCS) scores were rated between study group and control group. The mean score, obsession and compulsion scores of CY‐BOCS in the study group were significantly higher than they were in the control group (P < 0.05). The GABHS infections should be assessed in the etiology of OCD in children. Considering GABHS infections may help the treatment of OCD.
Research in Autism Spectrum Disorders | 2010
Ayhan Bilgiç; Kağan Gürkan; Serhat Türkoğlu; Ömer Faruk Akça; Birim Günay Kılıç; Runa Uslu
Journal of the American Academy of Child and Adolescent Psychiatry | 2007
Ayhan Bilgiç; Kağan Gürkan; Serhat Türkoğlu
Infant Behavior & Development | 2013
Koray Karabekiroglu; Runa Uslu; Emine G. Kapci-Seyitoglu; Burcu Özbaran; Didem Öztop; Özlem Özel-Özcan; Burak Dogangun; Sahika Gülen-Sismanlar; Işık Görker; Tülin Fidan; Kayhan M. Bahali; Yasar Barut; Kağan Gürkan; Birim Günay Kılıç; Pinar Ay; Beril Taskin; Nusin Bilgin; Ebru Çengel-Kültür
Çocuk ve Gençlik Ruh Sağlığı Dergisi | 2006
Ayhan Bilgiç; Kiliç, Birim, Günay; Kağan Gürkan; Ayla Aysev
Düşünen Adam: The Journal of Psychiatry and Neurological Sciences | 2006
Osman Abali; Metin Onur; Kağan Gürkan; Ömer Çelik; Ümran Tüzün
Journal of Pediatric Urology | 2008
Berk Burgu; Evren Süer; Kağan Gürkan; Runa Uslu; Tarkan Soygür