Kai Laustiola

Haemodynamic and hormonal responses to heat exposure in a Finnish sauna bath

SummaryEight healthy young men were studied during three periods of heat exposure in a Finnish sauna bath: at 80° C dry bulb (80 D) and 100° C dry bulb (100 D) temperatures until subjective discomfort, and in 80° C dry heat, becoming humid (80 DH) until subjective exhaustion. Oral temperature increased 1.1° C at 80 D, 1.9° C at 100 D and 3.2° C at 80 DH. Heart rate increased about 60% at 80 D, 90% at 100 D and 130% at 80 DH. Plasma noradrenaline increased about 100% at 80 D, 160% at 100 D and 310% at 80 DH. Adrenaline did not change. Plasma prolactin increased 2-fold at 80 D, 7-fold at 100 D and 10-fold at 80 DH. Blood concentrations of the beta-endorphin immunoreactivity at 100 D, adrenocorticotropic hormone (ACTH) at 100 D and 80 DH, growth hormone at 100 D and testosterone at 80 DH also increased, but cortisol at 80 D and 100 D decreased. The plasma prostaglandin E2 and serum thromboxane B2 levels did not change. Patterns related to heat exposure were observed for heart rate, plasma noradrenaline, ACTH and prolactin in the three study periods.

Cigarette Smoking Alters Sympathoadrenal Regulation by Decreasing the Density of β2-adrenoceptors. A Study of Monitored Smoking Cessation

We report the effects of monitored smoking cessation on adrenergic regulation in chronic smokers. The α2 adrenoceptor density of mononuclear leukocytes (MNLs) and plasma catecholamines was analyzed before cessation and 2.3, and 8 weeks after cessation. We found a progressive increase in α-adrenoceptor density after smoking cessatin. During smoking the α-adrenoceptor density after smoking was 1,456

Endothelium-dependent and -independent effects of exogenous ATP, adenosine, GTP and guanosine on vascular tone and cyclic nucleotide accumulation of rat mesenteric artery

83 (mean

Divergent effects of atenolol, practolol and propranolol on the peripheral metabolic changes induced by dynamic exercise in healthy men

SEM) bindings sites per cell (n = 10), whereas 3 weeks after cessation the the density was 1,774

Influence of continued smoking and some biological risk factors on restenosis after percutaneous transluminal coronary angioplasty

157 sites per cell (n = 10: < 0.05), and at 8 weeks, 1,900

Enalapril versus atenolol in the treatment of hypertensive smokers.

227 sites per cell in (n = 8; p < 0.05), representing an overall increase of 23% Smoking cessation had no effect on binding affinity nor on lymphocyte subgroup distribution. The density of MNL cell β-adrenoceptors in age-matched nonsmoking men was higher, at 1,896