Kang-Un Choi

Hemorheologic Alterations in Patients with Type 2 Diabetes Mellitus Presented with an Acute Myocardial Infarction

Background Hemorheologic indices are known to be related to vascular complications in variable clinical settings. However, little is known about the associations between hemorheologic parameters and acute myocardial infarction (AMI) in type 2 diabetes mellitus (T2DM). The purpose of this study was to demonstrate the changes of hemorheologic environment inside of blood using hemorheologic parameters, especially the elongation index (EI) and critical shear stress (CSS) in diabetics with versus without AMI. Methods A total of 195 patients with T2DM were enrolled. Patients were divided into the study group with AMI (AMI+, n=77) and control group (AMI−, n=118) who had no history of coronary artery disease. Hemorheologic parameters such as EI and CSS were measured and compared between the two groups. Results The EI was lower (30.44%±1.77% in AMI+ and 31.47%±1.48% in AMI−, P<0.001) but the level of CSS was higher (316.13±108.20 mPa in AMI+ and 286.80±85.34 mPa in AMI−, P=0.040) in the AMI+. The CSS was significantly related to the erythrocyte sedimentation rate (R2=0.497, P<0.001) and use of dipeptidyl peptidase-4 inhibitors (R2=0.574, P=0.048). Conclusion Diabetics with AMI resulted in adverse hemorheologic changes with lower EI and higher CSS compared to diabetic subjects without AMI. Evaluation of the hemorheologic parameters may provide valuable supplementary information for managing patients with AMI and T2DM.

TCT-167 Clinical impact of body mass index in old age patients with acute myocardial infarction

The clinical impact of BMI especially in old age patients have not yet been sufficiently evaluated. The aim of this study was to investigate the clinical impact of body mass index (BMI) in old age patients (≥80 years) with acute myocardial infarction (AMI). We analyzed a total of 2,489 AMI

SEVERE CHEST PAIN WITH MID-VENTRICULAR OBSTRUCTION IN PATIENTS WITH HYPERTHYROIDISM

Mid-ventricular obstruction (MVO) occurs in approximately 10% of patients with hypertrophic cardiomyopathy (HCM). Without HCM, small ventricular chamber or hypercontractility may play an important role in producing dynamic MVO. A 50 year-old female patient was consulted to cardiology department for

RECURRENT HYPOTENSION DURING HEMODIALYSIS ASSOCIATED WITH DOUBLE-CHAMBERED RIGHT VENTRICLE IN HYPERTROPHIC CARDIOMYOPATHY PATIENT

Double-chambered right ventricle (DCRV) is a rare heart defect in which the right ventricle (RV) is separated into a high pressure proximal chamber and a low pressure distal chamber. Involvement of RV in hypertrophic cardiomyopathy (HCM) complicated with DCRV is very uncommon, however, can cause