Kanji Inoue

Transluminal endovascular branched graft placement for a pseudoaneurysm: Reconstruction of the descending thoracic aorta including the celiac axis

We I have previously reported a successful transluminal endovascular placement of a branched graft that had a sidearm extending into the left subclavian artery for repair of type B aortic dissection. The sidearm was properly positioned by catching and pulling back the free end of a detachable wire attached to its end by means of a gooseneck snare wire, which was percutaneously inserted through the left brachial artery. However, it is impossible to place sidearm grafts into the celiac axis and renal arteries in a similar manner. In this article, we describe a new method of inserting a sidearm into the celiac axis and report successful transluminal endovascular repair of a pseudoaneurysm with the use of the branched graft. A 73-year-old man with severe chronic renal failure requiring hemodialysis had previously undergone surgical repair of an aneurysm of the descending thoracic aorta. However, a pseudoaneurysm of the descending thoracic aorta resulting from dehiscence of the suture line at the proximal and distal anastomoses after composite graft surgery had continued to dilate, reaching 80 mm in diameter. Although surgical treatment was attempted, the effort was given up because of marked adhesions caused by a previous thoracotomy. He was admitted to our hospital for endovascular treatment of the pseudoaneurysm. The structure of the Inoue endovascular graft was previously described in detail. 2 The graft was constructed from a Dacron polyester fabric cylinder and the surface was supported by multiple rings of extra-flexible nickel titanium wire. The patient gave informed consent in conformance with the protocols approved by the institutional review board of Takeda Hospital. Endovascular grafting with the straight graft was performed on June 28, 1995. Although the proximal communication was completely obliterated after the procedure, the distal communication persisted because the distal orifice of the pseudoaneurysm was in close proximity to the celiac axis. Although transluminal embolization was

Clinical Application of Transluminal Endovascular Graft Placement for Aortic Aneurysms

BACKGROUND In recent years, transluminal endovascular graft placement techniques have been developed for the treatment of aortic aneurysms. We report our initial clinical experience with endovascular graft placement using a graft developed in our laboratory. METHODS The procedure was performed in 20 patients with a diagnosed aortic aneurysm. The graft is constructed from a Dacron cylinder, and the surface of the graft is supported with multiple rings of extraflexible wire. After the compactly folded graft is delivered through the sheath to the predetermined target point, the graft is deployed and then pressed against the vessel by balloon inflation. Straight graft insertion was attempted in 10 patients, bifurcated graft insertion in 8, and branched graft insertion in 2. RESULTS Graft placement was successful in 19 of the patients and unsuccessful in 1. There were no cases of graft migration, aneurysm rupture, or graft destruction during a mean follow-up period of 9 months. CONCLUSIONS Initial clinical results demonstrated the efficacy and safety of endovascular graft placement using this graft.

Transluminal repair of an infrarenal aortoiliac aneurysm by a combination of bifurcated and branched stent grafts

Transfemoral endovascular repair with a combination of bifurcated and branched stent grafts enables aortoiliac reconstruction with internal iliac perfusion preserved. We report a case of successful endovascular repair of aortoiliac aneurysm with use of a bifurcated and branched stent‐graft. Cathet. Cardiovasc. Intervent. 47:491–494, 1999.

Endovascular Treatment of a Giant Aortic Arch Aneurysm With a Triple-Branched Stent Graft

An 86-year-old woman was referred for treatment of a rapidly enlarging aortic arch aneurysm, which had been monitored for 2 years with serial computed tomography (CT) scans. The size of the aneurysm had been 65 mm 2 years previously, but it had enlarged to 110 mm at the most recent examination (Figure 1). The patient complained of hemosputum and back pain. The risk of rupture was considered very high if the aneurysm was left untreated; however, thoracotomy was considered high risk because of the patient’s age. After obtaining the informed …

Registration of Preoperative CTA and Intraoperative Fluoroscopic images for Assisting Aortic Stent Grafting

We investigated a registration method between preoperative 3D-CTA and intraoperative fluoroscopic images during intervention. Our final goal is assisting endovascular stent grafting for aortic aneurysm. In our method, DRR (Digitally Reconstructed Radiograph) are generated by voxel projection of 3D-CTA after extracting an aorta region. By increasing/decreasing CT value in the aorta region of CTA, DRR with/without contrast media injection are obtained. Subsequently we calculate matching measures between DRR and fluoroscopic images iteratively by changing imaging parameters. The most similar DRR to fluoroscopic image is selected. We investigated characteristics of several matching measures using simulated fluoroscopic images. From simulation results, we use M-estimator of residual in our method. From an application example to clinical data, registration was successfully applied by M-estimator of residual.

A System for Computer-Assisted Design of Stent-Grafts for Aortic Aneurysms Using 3-D Morphological Models

A three-dimensional model was constructed from helical CT images for abdominal aortic aneurysm (AAA) and thoracic aortic aneurysm (TAA). A stent-graft was designed and positioned endoluminally on the computer. One hundred and nine stent-grafts for 101 patients were designed by this method and deployed well in all patients. The design time was reduced from 4 to 0.5 hr.

Percutaneous transvenous mitral commissurotomy for mitral stenosis patients with markedly severe mitral valve deformity: Immediate results and long-term clinical outcome

In conclusion, to evaluate the efficacy and safety of PTMC for mitral stenosis patients with markedly severe valve deformity, we performed PTMC in 17 patients with severe mitral stenosis assessed by echocardiography (echo score > or = 12). This study demonstrates that PTMC can be performed safely and is clinically useful in treating the mitral stenosis patient with a markedly severe valve deformity.

Percutaneous balloon valvuloplasty for bioprosthetic mitral valve stenosis

Percutaneous transcatheter mitral valvuloplasty is the indicated treatment of choice for symptomatic native mitral valve stenosis, but there have been limited reports of successful procedures of balloon valvuloplasty for bioprosthetic mitral valve stenosis. We present the case of a 62-year-old woman suffering from progressive dyspnea due to bioprosthetic mitral valve stenosis. The measured mean pressure gradient across the mitral valve was 30 mmHg and the mitral valve area was 0.73 cm2. Redoing mitral replacement was considered high risk and was refused by the patient. Percutaneous balloon valvuloplasty was performed with an Inoue balloon catheter inflated to 20 mm. The patient’s symptoms immediately improved after the procedure, with no procedure-related complications. The mean pressure gradient across the valve decreased to 19 mmHg, and the mitral valve area increased to 1.21 cm2 in postprocedural echocardiography. We conducted a literature search and identified 26 cases of balloon valvuloplasty for degenerated bioprosthetic valves. Of these, 14 cases were bioprosthetic mitral valves, and the results were favorable. However, more case reports are required to establish an evidence base for future expert recommendation of balloon valvuloplasty of prosthetic mitral valve. Meanwhile, balloon valvuloplasty will serve a niche role in highly selected patients with prosthetic mitral valve stenosis.

Transvenous mitral commissurotomy examined with transesophageal echocardiography

SummaryTransvenous mitral commissurotomy (TMC) was conducted with transesophageal echocardiography (TEE) in two patients with mitral stenosis. It was possible to see clearly not only the intracardiac structures to be examined by TMC, such as the right and left atria, interatrial septum, and mitral valve, but also the instruments used in TMC, such as the catheter, guidewire, and balloon. It was possible to determine the positional relation between the intracardiac structures and instruments. We could observe all procedures other than Brockenbroughs procedure by both TEE and fluoroscopy at the same time. Although safety and reliability cannot be confirmed from just the two present cases, TEE appears to be applicable to TMC.

A novel approach to prevent spinal cord ischemia: Inoue stent graft with a side branch of small caliber for the reconstruction of the artery of Adamkiewicz

OBJECTIVES Paraplegia remains a serious complication after endovascular repair of thoracic aortic aneurysms, and it has been reported that paraplegia might be due to ischemia of the artery of Adamkiewicz. This study investigates the feasibility of an Inoue stent graft with a side branch of a small caliber for the reconstruction of the intercostal artery branching the artery of Adamkiewicz. METHODS Branched Inoue stent grafts were implanted into the thoracic aorta and 11th intercostal artery of 5 mongrel dogs. The side branch measured 3 x 5 mm and contained a bare-metal coronary stent for fixing to the intercostal arterial wall. Aortography and selective angiography of the 11th intercostal artery were performed before and immediately after implantation and after 1, 4, 8, and 12 weeks. The luminal diameter of the intercostal artery before implantation was 2.4 +/- 0.3 mm. RESULTS All stent grafts were successfully deployed. The main body of the graft did not develop endoleak or migrate, and the side branch remained patent for 12 weeks. Angiography performed 1 week postoperatively revealed smooth flow with slight stenosis (4.2% +/- 1.7%) along the side branches and the intercostal arteries in all dogs. Four weeks postoperatively, however, mild concentric stenosis (38% +/- 16%) along the side branch was observed in 4 of the 5 dogs. The percent stenosis at 8 and 12 weeks was 38% +/- 15% and 33% +/- 11%, respectively; these values were not significantly different from the value at 4 postoperative weeks. CONCLUSIONS A novel Inoue stent graft with a side branch of small caliber was successfully deployed into the canine thoracic aorta and intercostal artery; the side branch remained patent for 12 weeks. This novel technique may enable endovascular reconstruction of the Adamkiewicz artery.