Kapil Bhesaniya

Measurement and Correlation for Solubility of Some Pyrimidine Derivatives in Different Solvents

Some new pyrimidine derivatives have been synthesized and their characterization was done by IR, NMR, and mass spectral data. The solubility of these synthesized compounds has been studied in methanol, N,N dimethylformamide (DMF), and carbon tetrachloride (CCl4) by gravimetrical method from 298.15 to 328.15 K under atmospheric pressure and the solubility data were correlated against temperature. The solubility is found to increase with temperature and order of solubility is DMF > methanol > CCl4. The experimental solubility data is correlated with the modified Apelblat equation. Some thermodynamic parameters such as dissolution enthalpy, Gibbs energy of dissolution, and entropy of mixing have also been calculated.

Decomposition Kinetics of Some New Schiff Bases Derived From 4-Amino Benzoic Acid

Some new Schiff bases have been synthesized from 4- amino benzoic acid and their thermal analysis have been carried out by TG technique. TG data of decomposition have been analysed for the kinetic parameters using Freeman-Carroll method. From the observed curves, various kinetic parameters such as order of degradation (n), energy of activation (E), frequency factor (A) and entropy change (∆S) have been evaluated. Further, thermal stability of Schiff bases have been determined, which is found to depend on the type of substituent present in the compounds.