Karel Škoch

Selective Gold-Catalysed Synthesis of Cyanamides and 1-Substituted 1H-Tetrazol-5-Amines from Isocyanides

The newly discovered gold-catalysed reaction of isocyanides with hydrazoic acid generated in situ from trimethylsilyl azide and methanol (or, alternatively, from NaN3 /AcOH) produces either cyanamides or 1-substituted 1H-tetrazol-5-amines, depending on the amount of available HN3 . The reaction proceeds selectively and in generally high yields of either product, thus providing a particularly convenient access to a wide range of substituted 1H-tetrazol-5-amines that are rather difficult to access otherwise.

The crystal structure of (5-methyl-1,2,4-oxadiazol-3-yl)ferrocene, C13H12FeN2O

Abstract C13H12FeN2O, monoclinic, P21/n (no. 14), a = 5.9035(2) Å, b = 20.7111(6) Å, c = 9.1403(3) Å, β = 90.0762(16)°, V = 1117.57(6) Å3, Z = 4, Rgt(F) = 0.0282, wRref(F2) = 0.0656, T = 150(2) K.