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Dive into the research topics where Karen Booth is active.

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Featured researches published by Karen Booth.


Interactive Cardiovascular and Thoracic Surgery | 2012

Catheter-induced pulmonary artery rupture: haemodynamic compromise necessitates surgical repair

Karen Booth; Gavin Mercer-Smith; Chris McConkey; Haralabos Parissis

Pulmonary artery haemorrhage is thankfully a very rare complication following pulmonary artery catheter insertion. It carries a significant mortality of 50%, and most cases are managed conservatively or with embolization therapy. We present an occult case, in which a patient presented with haemodynamic compromise without haemoptysis or significant haemothorax, who required surgical intervention. We discuss surgical treatment management options and the need for a high index of clinical suspicion to prevent mortality from this condition.


Asian Cardiovascular and Thoracic Annals | 2012

Teicoplanin-induced neutropenic sepsis mimicking endocarditis.

Karen Booth; Haralambos Parissis

Teicoplanin is a less toxic replacement for vancomycin in most situations where resistant organisms are encountered, and is therefore the drug of choice. As a commonly used drug in cardiac surgery, we treated a case of presumptive endocarditis with teicoplanin that caused neutropenic sepsis, unmasked on withdrawal of treatment.


The Journal of Thoracic and Cardiovascular Surgery | 2018

Training cardiothoracic surgeons of the future: The UK experience

Louise Kenny; Karen Booth; Kathrin Freystaetter; Greta Wood; Gary Reynolds; Sridhar Rathinam; Narain Moorjani

Objective: The study aimed to assess targeted simulation courses, including live animal operating, as complementary training tools with regard to 2 key surgical skills in early cardiothoracic surgeon training. Methods: Twenty UK surgical trainees (equivalent to cardiothoracic surgery resident physicians in the United States) in their first year of residency training were evaluated. Assessment of skills in pulmonary wedge resection and cardiopulmonary bypass were undertaken before and after 2 boot camp‐style courses, including live animal operating (boot camp 1 and boot camp 2). Resident performance was evaluated by surgical trainers using objective structured assessment of technical skills matrices. Trainers completed a survey on skill development and trainer confidence in the trainee precourse and postcourse. Results: Trainee assessment scores pre‐ and postcourses were analyzed using a 2‐tailed Wilcoxon signed‐rank test demonstrating a significant improvement in trainee performance in boot camp 1 in performing cardiopulmonary bypass (median score, 21 precourse and 28 postcourse; P = .001) and pulmonary wedge resection (median score, 25 precourse and 32 postcourse; P = .012), and in boot camp 2, in performing cardiopulmonary bypass (median score, 28 precourse and 30.5 postcourse; P = .018) and pulmonary wedge resection (median score, 31.5 precourse and 37 postcourse; P = .018). Trainers reported increased confidence and decision‐making competency of residents and increased confidence of trainers to allow more participation in management. It was found that 83.3% of trainers would support trainee attendance in subsequent years. Conclusions: Live animal operating as a component of targeted cardiothoracic surgery skill training courses significantly improves technical skills, builds confidence of surgical trainers in resident physicians’ practice, and should be supported by the surgery community.


The Japanese Journal of Thoracic and Cardiovascular Surgery | 2015

A case of focal lung infarction following right upper lobectomy in case of undeveloped lung fissure

Haralabos Parissis; Karen Booth; Bassel Al-Alao

Abstract We present a case of infarction of residual upper lobe tissue during right upper lobectomy. We believe that although the blood supply to the upper lobe had been isolated and divided in order to perform the right upper lobectomy, residual right upper lobe had been left behind secondary to “poorly estimated” staple separation of the upper from the middle lobe in a patient with non-developed oblique fissure. We suggest that in this situation the upper lobe bronchus should be identified and clamped and the lung re-inflated in order to accurately demarcate the borders of the upper and middle lobe prior to the application of the stapler to prevent infarction of residual upper lobe tissue. Therefore, this case emphasises that routine lung inflation during fissure development in right upper lobectomy may prevent unpredictable complications.


Case Reports in Medicine | 2014

Constrictive Pericarditis and Rheumatoid Nodules with Severe Aortic Incompetence

Rory Beattie; Karen Booth; Brian Herron; Mary N. Sheppard; Haralambos Parissis

The case of a female patient presenting with constrictive rheumatoid pericarditis and aortic incompetence secondary to valvular rheumatoid nodules is described along with a review of the literature with the aim to highlight this rare cause of aortic insufficiency.


The Annals of Thoracic Surgery | 2018

Novel Management of Atrial Septal Defect at Time of Lung Transplantation

Marian Urban; Karen Booth; John J. O’Sullivan; John H. Dark

We present a case of a young female patient with end-stage lung failure because of pulmonary arterial hypertension who was failing maximal medical therapy and was listed for a single sequential lung transplantation. The challenge of the case was a concomitant presence of a large atrial septal defect. The novelty of our approach was a device closure of atrial septal defect before performing transplantation with the use of intraoperative venoarterial extracorporeal membrane oxygenation.


Clinical Transplantation | 2018

Donor and recipient risk factor analysis of inferior postheart transplantation outcome in the era of durable mechanical assist devices

Marian Urban; Karen Booth; Stephan Schueler; Ivan Netuka; Guy A. MacGowan

The study objective is to quantify the impact of donor and recipient variables on heart transplant survival in recipients with a significant proportion of implanted continuous‐flow left ventricular assist devices (LVADs). This is a prospective cohort study of International Society for Heart and Lung Transplantation (ISHLT) Registry that includes all primary heart‐alone transplants in adult recipients (January 2005 and June 2013, N = 15 532, 27% LVADs). Donor and recipient characteristics were assessed for association with death or graft failure within 90 days and between 90 days and 5 years after transplantation. On Cox proportional hazard model donor cause of death other than head trauma (hazard ratio [HR] 1.985, P < 0.0001), recipient congenital (HR 2.7555, P < 0.0001) and ischemic (HR 1.165, P = 0.0383) vs dilated etiology and female donor heart transplanted into male recipient (HR 1.207, P = 0.0354) were predictors of death or graft failure within 90 days. Between 90 days and 5 years, donor cigarette use (HR 1.232, P = 0.0001), recipient cigarette use (HR 1.193, P = 0.0003), diabetes (HR 1.159, P = 0.0050), arterial hypertension (HR 1.129, P = 0.0115), and ischemic vs dilative cardiomyopathy had an increased probability of death or graft failure.


The Annals of Thoracic Surgery | 2017

Managing a Mycotic Thoracoabdominal Aneurysm: The Importance of Molecular Diagnostics

Christopher D. Bayliss; Karen Booth; Robin Williams; John H. Dark; Kate Gould

Pneumococcal mycotic aneurysms are rare and associated with significant mortality and morbidity. Early intravenous antibiotic therapy and surgical intervention is the mainstay of treatment. Pneumococci frequently autolyze in blood cultures, making microbiological diagnosis challenging. We present the case of a man in his mid 70s with multiple thoracoabdominal mycotic aneurysms. Surgery was performed to a threatening saccular aortic arch aneurysm. Samples were sent for microbiological analysis and all were culture negative. The samples were then referred for bacterial 16S ribosomal RNA sequencing, which revealed evidence of infection with Streptococcus pneumoniae.


Asian Cardiovascular and Thoracic Annals | 2017

Descending aortic aneurysm in Wiskott-Aldrich syndrome: options for repair

Greta Wood; Karen Booth; Zahid Khan; Tina Biss; Chandrika Roysam; John H. Dark

We report open surgical repair of a previously stented descending thoracic aneurysm in a patient with Wiskott-Aldrich syndrome and a platelet count <10 × 109·L−1. The same patient was described previously in a report of the first endovascular stent in this form of vasculitis. We describe the pre- and intraoperative management, and suggest a change in strategy in this setting.


Asian Cardiovascular and Thoracic Annals | 2016

Sarcoidosis or acute coronary syndrome: Easily distinguishable?

William Dominic Marley; Karen Booth; Reuben Jeganathan

Sinus of Valsalva aneurysm is a rare presenting feature of ST-elevation myocardial infarction. We describe such a case which resolved with thrombolysis, and on further investigation, the patient was found to have a large sinus of Valsalva aneurysm. Abnormal gross pathology at the time of surgery was suspected to be aortitis which was only confirmed on postmortem examination 6 months later. We highlight the importance of working closely with a pathologist when aortitis is suspected, because failure to treat it medically results in a poor outcome.

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Marian Urban

University of Nebraska Medical Center

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Mark T. Jones

University Hospital of South Manchester NHS Foundation Trust

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