Karen Dempsey

Internationally Distributed Frozen Oyster Meat Causing Multiple Outbreaks of Norovirus Infection in Australia

BACKGROUND Between November 2003 and January 2004, outbreaks of norovirus in 3 Australian jurisdictions involving 83 cases of illness were associated with imported oyster meat. METHODS Cohort studies were conducted in 2 jurisdictions to identify relative risks of illness for the consumption of oysters. A case series was conducted in the third jurisdiction. RESULTS The cohort studies conducted in the first 2 jurisdictions identified relative risks of illness of 17 (95% confidence interval, 5-51) and 35 (95% confidence interval, 5-243), respectively, for the consumption of oysters. Multiple strains of norovirus were detected in fecal specimens from 8 of 14 patients and in 1 of the 3 batches of implicated oyster meat using seminested reverse-transcriptase polymerase chain reaction methods. Traceback investigations revealed that all oyster meat was harvested from the same estuary system in Japan within the same month. CONCLUSIONS These outbreaks demonstrate the potential of foodborne disease to spread internationally and the need for national and international collaboration to investigate such outbreaks. Foodborne illness related to norovirus is underestimated because of underreporting of human cases and challenges in laboratory detection of viruses in foods, both of which can delay public health action.

Hepatocellular carcinoma in Australia's Northern Territory: high incidence and poor outcome

Objective: To describe the epidemiology, clinical features, management and outcomes of hepatocellular carcinoma (HCC) in the Northern Territory over the past decade.

Trends in cancer incidence and survival for Indigenous and non-Indigenous people in the Northern Territory.

Objective: To assess trends in cancer incidence and survival for Indigenous and non‐Indigenous Australians in the Northern Territory.

Trends in Indigenous and non‐Indigenous caesarean section births in the Northern Territory of Australia, 1986–2012: a total population‐based study

To examine trends in caesarean section deliveries and factors associated with these trends for Indigenous and non‐Indigenous mothers.

Cohort profile: The Pregnancy and Neonatal Diabetes Outcomes in Remote Australia (PANDORA) Study

I-Lynn Lee, Brydie Purbrick, Federica Barzi, Alex Brown, Christine Connors, Cherie Whitbread ... et al.