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Dive into the research topics where Karen Moses is active.

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Featured researches published by Karen Moses.


Clinical Psychology & Psychotherapy | 2011

Preliminary validation of an ultra‐brief version of the Penn State Worry Questionnaire

David Berle; Vladan Starcevic; Karen Moses; Anthony J. Hannan; Denise Milicevic; Peter Sammut

The Penn State Worry Questionnaire (PSWQ) is widely regarded as the gold standard self-report questionnaire for pathological worry. However, the factorial structure of the scale remains contentious. We sought to determine whether a psychometrically sound brief version of the PSWQ, which avoids contentious items and yet incorporates the essential features of pathological worry, could be derived from the existing PSWQ item pool. After inspecting items of the PSWQ and the findings of previous factor analytic studies, three items were selected that capture the essence of pathological worry (i.e., high frequency, perceived uncontrollability and multiple domains of worry), according to the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition). We then compared the psychometric properties of the 3-item PSWQ with the full PSWQ in a sample of 225 clients attending an anxiety disorders clinic. Despite its brevity, the 3-item PSWQ had internal consistency comparable with that of the standard PSWQ, and performed equally well with regards to convergent and discriminant validity, in screening for a generalized anxiety disorder diagnosis and in detecting change with treatment. The 3-item ultra-brief version of the PSWQ is quick to administer, simple to score and possesses psychometric properties very similar to the 16-item version. Further research should confirm the psychometric properties of the 3-item version when administered independently of the other items and assess the scales test-retest reliability.


Australian and New Zealand Journal of Psychiatry | 2011

Functions of Compulsions in Obsessive–Compulsive Disorder

Vladan Starcevic; David Berle; Vlasios Brakoulias; Peter Sammut; Karen Moses; Denise Milicevic; Anthony J. Hannan

Objectives: The key function of compulsions in obsessive–compulsive disorder (OCD) is to alleviate anxiety or distress caused by the obsessions, but compulsions may also have other functions. The main aim of this study was to systematically ascertain what motivates individuals with OCD to perform compulsions. Method: A total of 108 adults with OCD were assessed with the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and the Functions of Compulsions Interview. The latter instrument elicits the functions of identified compulsions. Results: The functions of 218 compulsions were identified. The mean number of functions per compulsion in the whole sample was 2.94 and the vast majority of compulsions (85.3%) were performed for more than one reason. The total number of functions of compulsions endorsed for the three main compulsions correlated with Y-BOCS total scores (r = 0.37, p < 0.001). Compulsions were most frequently performed automatically and to decrease distress or anxiety, but there was substantial variation, depending on the type of compulsion. Hoarding was often performed for reasons not related to any other compulsion (involving a perceived need for collected objects), whereas ordering/symmetry/repeating compulsions were frequently performed to achieve a ‘just right’ feeling. Checking was frequently performed because of the belief that something bad or unpleasant would happen if one failed to check; washing/cleaning compulsions were most frequently performed to decrease distress or anxiety and automatically, and mental compulsions were performed automatically far more often than for other reasons. Conclusions: The majority of compulsions have more than one function and they are often performed automatically. The finding of different functions of compulsions in different types of compulsions provides some support to the subtyping of OCD on the basis of obsessions and compulsions. Identifying functions of compulsions allows better understanding of the functional relationship between obsessions and compulsions, which may have implications for cognitive-behavioural therapy of OCD.


Australian and New Zealand Journal of Psychiatry | 2013

Obsessive-compulsive personality disorder co-occurring with obsessive-compulsive disorder: Conceptual and clinical implications

Vladan Starcevic; David Berle; Vlasios Brakoulias; Peter Sammut; Karen Moses; Denise Milicevic; Anthony J. Hannan

Objectives: There are ongoing uncertainties in the relationship between obsessive–compulsive disorder (OCD) and obsessive–compulsive personality disorder (OCPD). This study aimed to test the proposition that OCPD may be a marker of severity of OCD by comparing groups of OCD individuals with and without OCPD on a number of variables. Method: A total of 148 adults with a principal diagnosis of OCD were administered the Mini International Neuropsychiatric Interview, Yale–Brown Obsessive–Compulsive Scale, Sheehan Disability Scale, Vancouver Obsessional Compulsive Inventory and Symptom Checklist 90-Revised. Participants with a DSM-IV diagnosis of OCPD were compared with those without OCPD. Results: Some 70 (47.3%) participants were diagnosed with OCPD. The groups of participants with and without OCPD did not differ significantly with respect to any of the demographic variables, clinician-rated severity of OCD, levels of disability and mean age of onset of OCD. All self-rated OCD symptom dimensions except for contamination and checking were significantly more prominent in participants with OCPD, as were all self-rated dimensions of psychopathology. Participants with OCPD had significantly more frequent hoarding compulsions and obsessions involving a need to collect and keep objects. Of Axis I disorders, only panic disorder was significantly more frequent in participants with OCPD than in those without OCPD. Conclusions: A high frequency of OCPD among individuals with OCD suggests a strong, although not necessarily a unique, relationship between the two conditions. This finding may also be a consequence of the blurring of the boundary between OCD and OCPD by postulating that hoarding and hoarding-like behaviours characterise both disorders. Results of this study do not support the notion that OCD with OCPD is a marker of clinician-rated severity of OCD. However, individuals with OCPD had more prominent OCD symptoms, they were more distressed and exhibited various other psychopathological phenomena more intensely, which is likely to complicate their treatment.


Australasian Psychiatry | 2011

Obsessive-Compulsive Spectrum Disorders: a Comorbidity and Family History Perspective

Vlasios Brakoulias; Vladan Starcevic; Peter Sammut; David Berle; Denise Milicevic; Karen Moses; Anthony J. Hannan

Objective: The concept of obsessive-compulsive spectrum disorders (OCSDs) has become so influential that there are proposals to introduce it into new diagnostic classificatory systems. The aim of this paper was to assess whether rates of comorbidity and family history of OCSDs in patients with obsessive-compulsive disorder (OCD) supported this concept. Method: Comorbidity and family history were assessed in a group of participants with a primary diagnosis of OCD, using structured clinical interviews. Rates of OCSDs and other anxiety disorders (OADs), excluding OCD, were compared. Results: Of the 77 OCD participants assessed, the most prevalent comorbid conditions were OADs: generalized anxiety disorder (34.6%), specific phobia (26.9%), social phobia (21.8%) and panic disorder (19.2%). The proposed OCSDs were less frequently comorbid: tic disorder (12.8%), trichotillomania (5.1%), hypochondriasis (3.8%) and body dysmorphic disorder (BDD) (3.8%). Similar trends were observed for a family history of these disorders. No participant reported a family history of an OCSD without a family history of an OAD. Conclusions: Although the concept of OCSDs has invigorated thinking in this complex diagnostic field, these results support the current association of OCD with OADs rather than with OCSDs.


Comprehensive Psychiatry | 2013

The characteristics of unacceptable/taboo thoughts in obsessive–compulsive disorder

Vlasios Brakoulias; Vladan Starcevic; David Berle; Denise Milicevic; Karen Moses; Anthony J. Hannan; Peter Sammut; Andrew J. Martin

BACKGROUND In the quest to unravel the heterogeneity of obsessive-compulsive disorder (OCD), an increasing number of factor analytic studies are recognising unacceptable/taboo thoughts as one of the symptom dimensions of OCD. AIMS This study aims to examine the characteristics associated with unacceptable/taboo thoughts. METHODS Using the Yale-Brown Obsessive-Compulsive Scale Symptom Checklist (YBOCS-SC) with 154 individuals with OCD, obsessive-compulsive symptoms were subjected to principal components analysis. The characteristics associated with the resulting symptom dimensions were then assessed using logistic and linear regression techniques. RESULTS Unacceptable/taboo thoughts comprised of sexual, religious and impulsive aggressive obsessions, and mental rituals. Higher scores on an unacceptable/taboo thoughts symptom dimension were predicted by higher Y-BOCS obsession subscores, Y-BOCS time preoccupied by obsessions scores, Y-BOCS distress due to obsessions scores, importance of control of thought ratings, male gender, and having had treatment prior to entering into the study. Unacceptable/taboo thoughts were also predicted by greater levels of hostility, and a past history of non-alcohol substance dependence. CONCLUSIONS An unacceptable/taboo thought symptom dimension of OCD is supported by a unique set of associated characteristics that should be considered in the assessment and treatment of individuals with these symptoms.


Journal of Behavior Therapy and Experimental Psychiatry | 2012

Disgust propensity in obsessive–compulsive disorder: Cross-sectional and prospective relationships

David Berle; Vladan Starcevic; Vlasios Brakoulias; Peter Sammut; Denise Milicevic; Anthony J. Hannan; Karen Moses

BACKGROUND AND OBJECTIVES Findings from non-clinical samples suggest that disgust propensity is associated with contamination concerns in obsessive-compulsive disorder (OCD). However, studies of clinical samples have yielded conflicting results. We investigated the relationship between disgust propensity and OCD symptoms in a clinical sample and examined whether changes in disgust propensity are associated with changes in OCD symptoms. METHODS One hundred and nine OCD participants completed measures of disgust propensity and OCD symptoms. Sixty of these underwent a six-month follow-up assessment. RESULTS At the baseline assessment, disgust propensity was associated with all OCD symptom dimensions except hoarding. Changes in overall disgust propensity between baseline and the six-month follow-up assessment were associated with changes in overall self-reported OCD symptoms but not with changes in contamination-based OCD symptoms or changes in interviewer-assessed OCD symptoms. LIMITATIONS There was substantial participant attrition between the baseline and follow-up assessments. CONCLUSIONS Our study is the first to investigate prospective relationships between disgust propensity and OCD across a six-month interval. Our findings suggest that if there is an association between changes in disgust propensity and changes in contamination-based OCD symptoms its magnitude is likely to be small.


Australian and New Zealand Journal of Psychiatry | 2011

The nature and correlates of avoidance in obsessive–compulsive disorder

Vladan Starcevic; David Berle; Vlasios Brakoulias; Peter Sammut; Karen Moses; Denise Milicevic; Anthony J. Hannan

Objectives: Avoidance in obsessive–compulsive disorder (OCD) has been neglected by research. This study aimed (i) to collect information on the nature and frequency of avoidance in people with OCD and ascertain the types of obsessions related to avoidance; (ii) compare OCD individuals with and without avoidance, and (iii) determine predictors of avoidance in people with OCD. Method: A total of 124 OCD adults underwent a comprehensive assessment. Participants were asked whether they engaged in any avoidance behaviour because of their OCD, and the nature and number of instances of such avoidance were recorded. The instances of avoidance were grouped according to the type of obsession and compulsion that they were related to. Results: A total of 74 (59.7%) participants reported OCD-related avoidance. Avoidance was most commonly related to contamination obsessions. Almost 80% of all contamination obsessions and more than 50% of all aggressive obsessions were associated with avoidance, and contamination obsessions were significantly more common among the participants with avoidance. In contrast, very few obsessions about a need to collect and keep objects and obsessions about a need for ordering, arranging and doing things right or in an exact way were associated with avoidance; these types of obsessions were also significantly more common among the participants without avoidance. The strongest predictor of avoidance was the presence of contamination obsessions. Participants with avoidance had a significantly more severe OCD than those without avoidance. Conclusions: Avoidance is common in OCD, and it is particularly frequently associated with contamination obsessions. There is a weak link between avoidance and hoarding and between avoidance and ordering/arranging/symmetry obsessions and compulsions. These results, along with the finding that OCD with avoidance is a more severe illness, have implications for the future diagnostic criteria, description, subtyping and treatment of OCD and for its relationship with other anxiety disorders.


Journal of Nervous and Mental Disease | 2010

The Factor Structure of the Kessler-10 Questionnaire in a Treatment-Seeking Sample

David Berle; Vladan Starcevic; Denise Milicevic; Karen Moses; Anthony J. Hannan; Peter Sammut; Vlasios Brakoulias

The Kessler-10 (K10) questionnaire was developed as a screening instrument for nonspecific psychological distress. Although it was validated using epidemiological samples, it is increasingly being used in clinical settings. We sought to determine whether the factor structure of the K10 as established in epidemiological samples, could be replicated in a sample of treatment seeking adults. We used confirmatory factor analysis to investigate two established models of the factor structure of the K10 in a sample of clinic attendees. Neither the single factor model of Kessler et al., Psychol Med. 2002;32:959–976, nor the multifactorial model of Brooks et al., Psychol Assess. 2006;18:62–70 fitted the data. Respecification of the Kessler et al. model to reduce item redundancy did not result in adequate fit. These findings call into question the construct validity of the K10 in treatment seeking samples, and the suitability of the scale for clinical settings may need to be reconsidered.


Journal of Nervous and Mental Disease | 2013

Further support for five dimensions of obsessive-compulsive symptoms.

Vlasios Brakoulias; Vladan Starcevic; David Berle; Peter Sammut; Denise Milicevic; Karen Moses; Anthony J. Hannan; Andrew J. Martin

Abstract Attempts to explain the phenotypic heterogeneity of obsessive-compulsive disorder (OCD) have resulted in three to six OCD symptom dimensions. This study aimed to clarify the nature of these symptom dimensions using a self-report instrument (Vancouver Obsessional Compulsive Inventory [VOCI]) in addition to the clinician-rated Yale-Brown Obsessive Compulsive Scale–Symptom Checklist (YBOCS-SC). Participants (N = 154) were recruited to a study designed to specifically assess OCD symptom dimensions. Symptoms assessed via the YBOCS-SC and the VOCI were subjected to principal components analysis (PCA). Linear regression was used to assess therelationship between the YBOCS-SC–derived symptom dimensions and the VOCI symptom subscales. PCA of the YBOCS-SC and the VOCI revealed five OCD symptom dimensions that explained 68% and 60% of the variance, respectively. The results also supported a distinction between the doubt/checking symptom dimension and the unacceptable/taboo thoughts dimension that includes mental rituals. The YBOCS-SC–derived symptom components were predicted by their respective VOCI symptom subscale scores.


Psychiatry Research-neuroimaging | 2012

Interpersonal reassurance seeking in obsessive-compulsive disorder and its relationship with checking compulsions

Vladan Starcevic; David Berle; Vlasios Brakoulias; Peter Sammut; Karen Moses; Denise Milicevic; Anthony J. Hannan

This study aimed to examine interpersonal reassurance seeking (IRS) in obsessive-compulsive disorder (OCD) and the relationship between IRS and checking compulsions. One hundred and forty adults with OCD underwent a comprehensive assessment, which included obtaining information on seeking reassurance from others because of their obsessions. Sixty-seven (47.9%) participants reported IRS. They exhibited more psychopathology than participants without IRS, tended to have a greater overall severity of OCD and were far more likely to have checking compulsions. Participants with IRS also had more severe obsessions, suggesting that IRS plays a role as an additional coping strategy when obsessions are more prominent. The severity of obsessions and the absence of obsessions about a need to collect and keep objects were independent predictors of IRS, whereas the presence of obsessions about unintentional harm and not being married or in a de facto relationship independently predicted checking compulsions. Although a close relationship exists between IRS and checking compulsions, these results suggest important differences, with implications for understanding the factors that contribute to IRS and checking compulsions.

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Anthony J. Hannan

Florey Institute of Neuroscience and Mental Health

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David Berle

University of New South Wales

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Andrew J. Martin

University of New South Wales

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