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Dive into the research topics where Karin Bruynesteyn is active.

Publication


Featured researches published by Karin Bruynesteyn.


Annals of the Rheumatic Diseases | 2004

How the type of risk reduction influences required sample sizes in randomised clinical trials

Karin Bruynesteyn; Astrid J. B. Wanders; R. Landewé; D. van der Heijde

To increase change between groups, randomised clinical trials (RCT) often include patients with high risk for a particular outcome, by inclusion criteria that select predictors for that outcome. This increases the statistical power, and fewer patients are required for that RCT. The way in which patient selection influences the power, and thus sample size required, depends on how an intervention reduces the individual risk: by an absolute or relative risk reduction model.


Annals of the Rheumatic Diseases | 2005

Deciding on progression of joint damage in paired films of individual patients: smallest detectable difference or change

Karin Bruynesteyn; Maarten Boers; P.J. Kostense; S. ven der Linden; D. van der Heijde


Arthritis & Rheumatism | 2002

Determination of the minimal clinically important difference in rheumatoid arthritis joint damage of the Sharp/van der Heijde and Larsen/Scott scoring methods by clinical experts and comparison with the smallest detectable difference

Karin Bruynesteyn; Désirée van der Heijde; Maarten Boers; Ariane Saudan; Paul M. Peloso; Harold E. Paulus; Harry Houben; Bridget Griffiths; John Edmonds; Barry Bresnihan; Annelies Boonen; Sjef van der Linden


The Journal of Rheumatology | 2002

Detecting radiological changes in rheumatoid arthritis that are considered important by clinical experts: influence of reading with or without known sequence.

Karin Bruynesteyn; Désirée van der Heijde; Maarten Boers; Ariane Saudan; Paul M. Peloso; Harold E. Paulus; Harry Houben; Bridget Griffiths; John Edmonds; Barry Bresnihan; Annelies Boonen; Sjef van der Linden


The Journal of Rheumatology | 2003

Repair of erosions in rheumatoid arthritis does occur. Results from 2 studies by the OMERACT Subcommittee on Healing of Erosions.

John T. Sharp; Désirée van der Heijde; Maarten Boers; Annelies Boonen; Karin Bruynesteyn; Paul Emery; Harry K. Genant; Gertraud Herborn; Anne Grethe Jurik; Marissa Lassere; Fiona M. McQueen; Mikkel Østergaard; Charles Peterfy; Rolf Rau; Vibeke Strand; Siegfried Wassenberg; Barbara N. Weissman


The Journal of Rheumatology | 2001

Minimal clinically important difference in radiological progression of joint damage over 1 year in rheumatoid arthritis: preliminary results of a validation study with clinical experts.

Karin Bruynesteyn; D. van der Heijde; Maarten Boers; Marissa Lassere; A. Boonen; John Edmonds; Harry Houben; Harold E. Paulus; Paul M. Peloso; Ariane Saudan; S van der Linden


Annals of the Rheumatic Diseases | 2004

Radiography as primary outcome in rheumatoid arthritis: acceptable sample sizes for trials with 3 months' follow up.

Karin Bruynesteyn; R. Landewé; Sj van der Linden; D. van der Heijde


The Journal of Rheumatology | 2001

Robustness and generalizability of smallest detectable difference in radiological progression.

Marissa Lassere; D. van der Heijde; Kent R Johnson; Karin Bruynesteyn; Esmeralda Molenaar; A. Boonen; Arco C. Verhoeven; Paul Emery; Maarten Boers


Journal of Clinical Epidemiology | 2004

The Sharp/van der Heijde method out-performed the Larsen/Scott method on the individual patient level in assessing radiographs in early rheumatoid arthritis

Karin Bruynesteyn; Désirée van der Heijde; Maarten Boers; Sjef van der Linden; Marissa Lassere; Cees van der Vleuten


Arthritis Care and Research | 2002

Contribution of progression of erosive damage in previously eroded joints in early rheumatoid arthritis trials: COBRA trial as an example

Karin Bruynesteyn; Désirée van der Heijde; Maarten Boers; Arco C. Verhoeven; Annelies Boonen; Sjef van der Linden

Collaboration


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Maarten Boers

VU University Medical Center

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D. van der Heijde

Leiden University Medical Center

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Marissa Lassere

University of New South Wales

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