Is this you? Create Your Porfile
Avatar

Karin Keller

Network

Latest external collaboration on country level. Dive into details by clicking on the dots.

Explore More

Hotspot

Dive into the research topics where Karin Keller is active.

Explore More

Publication

Featured researches published by Karin Keller.

Bioorganic & Medicinal Chemistry Letters | 1996

Glycomimetic selectin inhibitors: (α-D-mannopyranosyloxy)methylbiphenyls

Brian Dupré; Huong Bui; Ian L. Scott; Robert V. Market; Karin Keller; Pamela J. Beck; Timothy P. Kogan

Abstract A novel class of biphenyl-based compounds were investigated for their ability to inhibit sialyl Lewis X (sLex) dependent binding of HL-60 cells to E- and P-selectin fusion proteins. Compounds ( 2b ) and ( 2h ) demonstrated improved binding as compared to both the natural ligand sLex and a previously reported inhibitor TBC-265 ( 1 , R = 3-CH2CO2H).

Journal of Medicinal Chemistry | 1997

Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-A selective antagonist.

Chengde Wu; Ming F. Chan; Fiona Stavros; Bore Gowda Raju; Ilya Okun; Seymour Mong; Karin Keller; Tommy Brock; Timothy P. Kogan; Richard Af Dixon

Journal of Medicinal Chemistry | 1995

Rational Design and Synthesis of Small Molecule, Non-oligosaccharide Selectin Inhibitors: (.alpha.-D-Mannopyranosyloxy)biphenyl-Substituted Carboxylic Acids

Timothy P. Kogan; Brian Dupre; Karin Keller; Ian L. Scott; Huong Bui; Robert V. Market; Pamela J. Beck; J. A. Voytus; B. M. Revelle; D. Scott

Archive | 1996

Di- and trivalent small molecule selectin inhibitors

Timothy P. Kogan; Brian Dupre; Ian L. Scott; Huong Bui; Kathy L. Wheeler; Karin Keller; Jamal M. Kassir

Archive | 2001

Formulation of sulfonamides for treatment of endothelin-mediated disorders

Natalie Blok; Chengde Wu; Patricia Woodard; Karin Keller; Timothy P. Kogan

Archive | 1999

Compounds that inhibit the binding of integrins to their receptors

Ronald J. Biediger; Vanessa O. Grabbe; George W. Holland; Jamal M. Kassir; Karin Keller; Timothy P. Kogan; Shuqun Lin; Robert V. Market; Bore Gowda Raju; Ian L. Scott; Chengde Wu

Archive | 1998

Sulfonamides for treatment of endothelin-mediated disorders

Chengde Wu; Natalie Blok; Timothy P. Kogan; Karin Keller; Patricia Woodard

Archive | 1997

Process of preparing alkali metal salys of hydrophobic sulfonamides

Natalie Blok; Chengde Wu; Karin Keller; Timothy P. Kogan

Journal of Medicinal Chemistry | 2001

Acyl substitution at the ortho position of anilides enhances oral bioavailability of thiophene sulfonamides: TBC3214, an ETA selective endothelin antagonist.

Chengde Wu; E. Radford Decker; Natalie Blok; Jian Li; Andree R. Bourgoyne; Huong Bui; Karin Keller; Vippra Knowles; Wen Li; Fiona Stavros; George W. Holland; Tommy A. Brock,†,‡ and; Richard A. Dixon

Archive | 1994

Binding of E-selectin or P-selectin to sialyl Lewisx or sialyl-Lewisa

Timothy P. Kogan; Brian Dupre; Ian L. Scott; Karin Keller; Huong Dao; Pamela J. Beck

Explore More

Collaboration

Dive into the Karin Keller's collaboration.

Top Co-Authors
Avatar

Timothy P. Kogan

Genentech

View shared research outputs
Top Co-Authors
Avatar

Ian L. Scott

Albany Molecular Research

View shared research outputs
Top Co-Authors
Avatar

Pamela J. Beck

University of Wisconsin-Madison

View shared research outputs
Top Co-Authors
Avatar

Robert V. Market

The Texas Heart Institute

View shared research outputs
Top Co-Authors
Avatar

Ronald J. Biediger

The Texas Heart Institute

View shared research outputs
Top Co-Authors
Avatar

Edward T.H. Yeh

Harvard University

View shared research outputs
Top Co-Authors
Avatar

George W. Holland

Hoffmann-La Roche

View shared research outputs
Top Co-Authors
Avatar

Richard A. Dixon

University of North Texas

View shared research outputs
Top Co-Authors
Avatar

Robert J. Bjercke

The Texas Heart Institute

View shared research outputs
Top Co-Authors
Avatar

Ronald G. Tilton

University of Texas Medical Branch

View shared research outputs
Explore More
Researchain Logo
Decentralizing Knowledge