Karl H. Michel | Researchain

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Tetrahedron Letters | 1991

A83543A-D, unique fermentation-derived tetracyclic macrolides

Herbert A. Kirst; Karl H. Michel; James W. Martin; Lawrence Creemer; Eddie H. Chio; Raymond C. Yao; Walter Mitsuo Nakatsukasa; Laverne Dwaine Boeck; John L. Occolowitz; Jonathan W. Paschal; Jack B. Deeter; Noel D. Jones; Gary D. Thompson

Abstract A multi-factored complex of structurally-unique macrolides was isolated from culture broths of a new species of Saccharopolyspora. The core structure consists of a 5,6,5-cis-anti-trans-tricyclic ring system fused to a 12-membered macrocyclic lactone, which is further substituted by an amino- and a neutral sugar.

Archive | 1992

Discovery, Isolation, and Structure Elucidation of a Family of Structurally Unique, Fermentation-Derived Tetracyclic Macrolides

Herbert A. Kirst; Karl H. Michel; Jon S. Mynderase; Eddie H. Chio; Raymond C. Yao; Walter M. Nakasukasa; Laverne Dwaine Boeck; John L. Occlowitz; Jonathon W. Paschal; Jack B. Deeter; Gary D. Thompson

Archive | 1991

Process for producing A83543 compounds

Laverne Dwaine Boeck; Hang Chio; Tom Edward Eaton; Otis Webster Godfrey; Karl H. Michel; Walter Mitsuo Nakatsukasa; Raymond C. Yao

The Journal of Antibiotics | 1989

Synthesis of new analogs of echinocandin B by enzymatic deacylation and chemical reacylation of the echinocandin B peptide: synthesis of the antifungal agent cilofungin (LY121019).

Manuel Debono; Bernard J. Abbott; David S. Fukuda; Mitchell Barnhart; K. E. Willard; R. M. Molloy; Karl H. Michel; J. R. Turner; Thomas F. Butler; Ann H. Hunt

Archive | 1982