Katherine M. Prioli

Cost-effectiveness of a community-integrated home-based depression intervention in older African Americans.

To test the cost‐effectiveness of a home‐based depression program: Beat the Blues (BTB).

Implementing a pharmacist-led, individualized medication assessment and planning (iMAP) intervention to reduce medication related problems among older adults with cancer.

OBJECTIVES Medication-related problems (MRP) affecting older adults are a significant healthcare concern and account for billions in medication-related morbidity. Cancer therapies can increase the prevalence of MRP. The objective of this study was to test the feasibility and effectiveness of implementing a pharmacist-led individualized medication assessment and planning (iMAP) intervention on the number and prevalence of MRP. MATERIALS AND METHODS This prospective pilot study enrolled oncology outpatients aged ≥65years. Intervention feasibility encompassed recommendation acceptance rate and intervention delivery time. The intervention was facilitated by pharmacists where patients received comprehensive medication management at baseline and at the 30- and 60-day follow-up. RESULTS Forty-eight eligible patients enrolled and 41 patients (85.4%) were included in the analysis. Mean age was 79.1years [range 65-101]; 66% women, 83% Caucasian, mean comorbidity count was 7.76. Forty-six percent of the pharmacist recommendations were accepted and the prevalence of MRP at baseline versus 60-day follow-up decreased by 20.5%. The average time to conduct the initial session was 22min versus 15min for the follow-up sessions. Resources needed included a tracking system for scheduling follow-up calls and a database for tracking acceptance of recommendations. A total of 123 MRP were identified in 95% of patients (N=39) with a mean of 3 MRP per patient. The mean reduction in number of MRP (3 at baseline versus 1.6 at 60-day follow-up) was 45.5%. CONCLUSIONS The pharmacist-led iMAP intervention was feasible and effective at reducing MRP. Additional inter-professional medication safety based interventions measuring patient-reported outcomes are still needed.

Knowledge, Activation, and Costs of the Pharmacists’ Pneumonia Prevention Program (PPPP): A Novel Senior Center Model to Promote Vaccination

Background: Vaccination is the best way to prevent pneumococcal disease (PD), but 40% of older adults remain unvaccinated nationwide, with even greater nonvaccination rates among African Americans (AAs). Prior studies suggest that insufficient knowledge contributes to low vaccination rates. The Pharmacists’ Pneumonia Prevention Program (PPPP) was designed to improve older adults’ knowledge about PD and pneumococcal vaccination (PV). Objective: To measure PPPP’s effect on knowledge and activation in a predominantly AA population and determine program costs. Methods: PPPP uses a senior center model with a pharmacist presentation, actors’ skit, and small-group action planning. Knowledge about PD risk, transmission, symptoms, and PV side effects was assessed at baseline (BL), postintervention (PT), and 3 months (M3) and analyzed using an intention-to-treat (ITT) approach. Actions taken (got vaccinated, spoke to doctor or pharmacist, discussed with family/friends) were assessed at M3. PPPP costs (

Cost of Purchased Versus Produced Plasma from Donor Recruitment Through Transfusion

US 2013) included staff time, PV, actor, and site fees. Results: Of 276 attending PPPP, 190 consented and were included in the ITT sample, which was largely black (80.5%) and female (76.3%) and had a mean age of 74.4 years. Knowledge improved by 46.8% (BL vs PT), with significant gains in all domains. At M3, knowledge improved by 54.2% vs BL, indicating sustained gains; 37.2% of previously unvaccinated participants reported receiving PV by M3. Program cost was

Tasks Involved In Platelet Production And Transfusion From The U.S. Hospital Perspective: Two Process Frameworks

119 per attendee. Conclusion: PPPP significantly improved PD and PV knowledge. It could be delivered more efficiently by holding larger events on fewer dates, staffing with volunteers where appropriate, and utilizing a local pharmacy to manage the vaccine supply.

Awareness and beliefs about pneumococcal and influenza vaccination among older african americans: Results from a survey of community-dwelling participants at an urban senior center

BackgroundPlasma is used to treat acquired coagulopathy or thrombotic thrombocytopenic purpura, or to reverse warfarin effect. Scant data are available, however, about its costs.ObjectiveTo estimate total costs of plasma from production through administration, from the perspective of a US hospital blood donor center (BDC).Study Design and MethodsSix sequential decision analytic models were constructed and informed by primary and secondary data on time, tasks, personnel, and supplies for donation, processing, and administration. Expected values of the models were summed to yield the BDC’s total cost of producing, preparing, and transfusing plasma. Costs (

Cost and Shelf-Life Implications of Pathogen-Reduced Platelets: A Hospital Budget Impact Model

US 2015) are reported for a typical patient using three units of plasma. Models assume plasma was obtained from whole blood donation and transfused in an inpatient setting. Univariate sensitivity analyses were performed to test the impact of changing inputs for personnel costs and adverse event (AE) rates and costs.ResultsBDC production cost of plasma was

Baseline Knowledge About Vaccines and Vaccine-Preventable Diseases Among Older Adults: Preliminary Baseline Analysis of the Vaccine Education Through Pharmacists and Senior Centers (VEPSC) Study

91.24/patient (

Exploring beliefs about pneumococcal vaccination in a predominantly older African American population: the Pharmacists’ Pneumonia Prevention Program (PPPP)

30.41/unit), a

Economic Implications of Pathogen Reduced and Bacterially Tested Platelet Components: A US Hospital Budget Impact Model

30.16/patient savings versus purchased plasma. Administration and monitoring costs totaled