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Kathleen M. Curnow

Cornell University

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Publication

Featured researches published by Kathleen M. Curnow.

Molecular Endocrinology | 1991

The product of the CYP11B2 gene is required for aldosterone biosynthesis in the human adrenal cortex

Kathleen M. Curnow; Maria Teresa Tusie-Luna; Leigh Pascoe; Rama Natarajan; Jia Li Gu; Jerry L. Nadler; Perrin C. White

Endocrine Reviews | 1994

Disorders of Steroid 11β-Hydroxylase Isozymes*

Perrin C. White; Kathleen M. Curnow; Leigh Pascoe

Proceedings of the National Academy of Sciences of the United States of America | 1992

Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2.

Leigh Pascoe; Kathleen M. Curnow; Liliya Slutsker; John M. C. Connell; Phyllis W. Speiser; Maria I. New; Perrin C. White

Proceedings of the National Academy of Sciences of the United States of America | 1993

Mutations in the CYP11B1 gene causing congenital adrenal hyperplasia and hypertension cluster in exons 6,7 and 8

Kathleen M. Curnow; Liliya Slutsker; Jiri Vitek; Trevor Cole; Phyllis W. Speiser; Maria I. New; Perrin C. White; Leigh Pascoe

Proceedings of the National Academy of Sciences of the United States of America | 1992

Mutations in the human CYP11B2 (aldosterone synthase) gene causing corticosterone methyloxidase II deficiency.

Leigh Pascoe; Kathleen M. Curnow; Liliya Slutsker; Ariel Rösler; Perrin C. White

Nature Structural & Molecular Biology | 1997

The amino acid substitutions Ser288Gly and Val320Ala convert the cortisol producing enzyme, CYP11B1, into an aldosterone producing enzyme.

Kathleen M. Curnow; Paolo Mulatero; Nicole Emeric-Blanchouin; Brigitte Aupetit-Faisant; Pierre Corvol; Leigh Pascoe

Molecular Endocrinology | 1992

Genetic analysis of the human type-1 angiotensin II receptor.

Kathleen M. Curnow; Leigh Pascoe; Perrin C. White

The Journal of Clinical Endocrinology and Metabolism | 1999

Prenatal Diagnosis and Treatment of 11β-Hydroxylase Deficiency Congenital Adrenal Hyperplasia Resulting in Normal Female Genitalia1

Barbara I. Cerame; Ron S. Newfield; Leigh Pascoe; Kathleen M. Curnow; Saroj Nimkarn; Thomas F. Roe; Maria I. New; Robert C. Wilson

The Journal of Clinical Endocrinology and Metabolism | 2001

Deletion hybrid genes, due to unequal crossing over between CYP11B1 (11beta-hydroxylase) and CYP11B2(aldosterone synthase) cause steroid 11beta-hydroxylase deficiency and congenital adrenal hyperplasia.

Stephanie Portrat; Paolo Mulatero; Kathleen M. Curnow; Jean-Louis Chaussain; Yves Morel; Leigh Pascoe

Molecular Endocrinology | 1993

Transcripts originating in intron 1 of the HSD11 (11 beta-hydroxysteroid dehydrogenase) gene encode a truncated polypeptide that is enzymatically inactive.

Jihad Obeid; Kathleen M. Curnow; Javier Aisenberg; Perrin C. White

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Perrin C. White

University of Texas Southwestern Medical Center

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Leigh Pascoe

Cornell University

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Liliya Slutsker

Cornell University

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Maria I. New

Icahn School of Medicine at Mount Sinai

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Phyllis W. Speiser

Cornell University

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Ariel Rösler

Hebrew University of Jerusalem

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Pierre Corvol

Collège de France

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Paolo Mulatero

University of Turin

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Ariel Rösler

Hebrew University of Jerusalem

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Barbara I. Cerame

Cornell University

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