Kazuhiko Imakawa
University of Missouri
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Publication
Featured researches published by Kazuhiko Imakawa.
American Journal of Reproductive Immunology | 1989
Yoshimi Niwano; Thomas R. Hansen; Mohammad Kazemi; Puthan-Veedu Malathy; H. D. Johnson; R. Michael Roberts; Kazuhiko Imakawa
ABSTRACT: Cells derived from the trophoblast tissue of a day 15 sheep conceptus released substances that inhibit incorporation of [3H]thymidine into phytohemagglutinin (PHA)‐stimulated ovine lymphocytes. This effect was partially reversed by addition of antiserum to ovine trophoblast protein‐1 (oTP‐1), a major secretory product of day 13–21 sheep conceptuses and a protein structurally and functionally related to α‐interferons (IFN‐α). Human IFN‐a, unlike dexamethasone, inhibits phytohemagglutinin‐induced lymphocyte blastogenesis without reducing interleukin‐2 (IL‐2) production by the cultures, and conditioned medium containing IL‐2 does not promote [3H]thymidine incorporation into ovine lymphocytes when oTP‐1 is present. Thus, oTP‐1, by virtue of being an IFN, may have a local immunomodulatory role by selectively inhibiting the proliferative responses of certain maternal immune cells to IL‐2.
Nature | 1987
Kazuhiko Imakawa; Russell V. Anthony; Mohammad Kazemi; Keith R. Marotti; H. Gregory Polites; R. Michael Roberts
Biology of Reproduction | 1990
C E Farin; Kazuhiko Imakawa; T. R. Hansen; J J McDonnell; Clifton N. Murphy; P W Farin; R.M. Roberts
Molecular Endocrinology | 1989
Kazuhiko Imakawa; Thomas R. Hansen; Puthan-Veedu Malathy; Russell V. Anthony; H. Gregory Polites; Keith R. Marotti; R. Michael Roberts
Molecular Endocrinology | 1989
C. E. Farin; Kazuhiko Imakawa; R. M. Roberts
Journal of interferon research | 1989
R.M. Roberts; Kazuhiko Imakawa; Y. Niwano; Mohammad Kazemi; Puthan-Veedu Malathy; Thomas R. Hansen; A.A. Glass; L.H. Kronenberg
Journal of interferon research | 1989
Thomas R. Hansen; Mohammad Kazemi; D. H. Keisler; Puthan-Veedu Malathy; Kazuhiko Imakawa; R. Michael Roberts
Molecular Endocrinology | 1990
Stephen W. Klemann; Junzhi Li; Kazuhiko Imakawa; James C. Cross; Harriet Francis; R. Michael Roberts
Molecular Endocrinology | 1990
Puthan-Veedu Malathy; Kazuhiko Imakawa; R. C. M. Simmen; R. M. Roberts
Archive | 1989
Peter J. Hansen; Kazuhiko Imakawa; R. Michael Roberts; William W. Thatcher
