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Kazuhiro Kitaori

Okayama University of Science

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Featured researches published by Kazuhiro Kitaori.

Tetrahedron | 1999

CsF in organic synthesis. Regioselective nucleophilic reactions of phenols with oxiranes leading to enantiopure β-blockers

Kazuhiro Kitaori; Yoshiro Furukawa; Hiroshi Yoshimoto; Junzo Otera

Abstract The two modes of the paths in the reaction of oxiranes with phenols are completely controlled by CsF. Glycidyl nosylate undergoes exclusive substitution at the C 1 position whereas the ring-opening (C-3 attack) occurs with epichlorohydrin, glycidol, and 1,2-epoxyalkanes. These reactions provide convenient access to enantiopure β-blockers.

Tetrahedron Letters | 1998

CsF in organic synthesis. The first and convenient synthesis of enantiopure bisoprolol by use of glycidyl nosylate

Kazuhiro Kitaori; Yoshiro Furukawa; Hiroshi Yoshimoto; Junzo Otera

Abstract The regioselective substitution of glycidyl nosylate with phenols is catalyzed by CsF in the presence of K2CO3 in DMF; this reaction enables the first and convenient synthesis of enantiopure bisoprolol.

Archive | 1996

Process for preparation of 1,4-benzodioxane derivative

Yoshiro Furukawa; Kazuhiro Kitaori; Keishi Takenaka

Chemical & Pharmaceutical Bulletin | 1997

A Pratical Synthesis of Optically Active Atenolol from Chiral Epichlorohydrin

Kazuhiro Kitaori; Yoshikazu Takehira; Yoshiro Furukawa; Hiroshi Yoshimoto; Junzo Otera

Archive | 1990

Process for producing optically active atenolol and intermediate thereof

Yoshikazu Takehira; Nobuaki Saragai; Kazuhiro Kitaori

Chemical & Pharmaceutical Bulletin | 1998

Convenient Preparation of Enantiopure Atenolol by Means of Preferential Crystallization

Kazuhiro Kitaori; Yoshikazu Takehira; Yoshiro Furukawa; Hiroshi Yoshimoto; Junzo Otera

Journal of Synthetic Organic Chemistry Japan | 2007

Development of Industrial Process for Optically Active Propanol Derivatives and Their Applications

Yoshiro Furukawa; Toshio Suzuki; Masafumi Mikami; Kazuhiro Kitaori; Hiroshi Yoshimoto

Advanced Synthesis & Catalysis | 2001

Integrated Chemical Process: Convenient Synthesis of Enantiopure 2‐Hydroxymethyl‐1,4‐benzodioxane Derivatives under Iterative Catalysis of CsF

Kazuhiro Kitaori; Yoshiro Furukawa; Hiroshi Yoshimoto; Junzo Otera

Synlett | 1998

CSF IN ORGANIC SYNTHESIS. A CONVENIENT SYNTHESIS OF CYCLOPROPANOLACTONE FROM GLYCIDYL NOSYLATE

Kazuhiro Kitaori; Masfumi Mikami; Yoshiro Furukawa; Hiroshi Yoshimoto; Junzo Otera

Archive | 1997

Process for the preparation of glycidyl ethers

Yoshiro Furukawa; Kazuhiro Kitaori; Tetsuya Yanagimoto; Masafumi Mikami; Hiroshi Yoshimoto; Junzo Otera

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Hiroshi Yoshimoto

University of Tsukuba

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Yoshiro Furukawa

Harvard University

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Junzo Otera

Okayama University of Science

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Yoshikazu Takehira

Okayama University of Science

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Yoshiro Furukawa

Harvard University

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Toshio Suzuki

Niigata University

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