Kazumi Kikuchi | Researchain

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Featured researches published by Kazumi Kikuchi.

Tetrahedron Letters | 1989

A synthetic approach to discorhabdin alkaloids: Hypervalent iodine oxidation of p-substituted phenol derivatives to azacarbocyclic spirodienones

Yasuyuki Kita; Takayuki Yakura; Hirofumi Tohma; Kazumi Kikuchi; Yasumitsu Tamura

Abstract Hypervalent iodine oxidation of O -silylated p -substituted phenols by phenyliodosyl bis (trifluoroacetate) (PIFA) in 2,2,2-trifluoroethanol gave azacarbocyclic spirodienones inn good yields.

Tetrahedron Letters | 1991

Hypervalent iodine oxidation of O-silylated phenol derivatives to azacarbocyclic spirodienones ; synthetic approach to the anticancer marine alkaloid, discorhabdin C

Yasuyuki Kita; Hirofumi Tohma; Masanao Inagaki; Kenji Hatanaka; Kazumi Kikuchi; Takayuki Yakura

Abstract Hypervalent iodine oxidation of O-silyated phenols bearing various types of aminoquinones at the p-position in 2,2,2-trifluoroethanol gave azacarbocyclic spirodienones in good yields and application of this reaction to the synthetic approach to discorhabdin C was also described.

Journal of Organic Chemistry | 1991

Hypervalent iodine oxidation of N-acyltyramines: synthesis of quinol ethers, spirohexadienones, and hexahydroindol-6-ones

Yasuyuki Kita; Hirofumi Tohma; Kazumi Kikuchi; Masanao Inagaki; Takayuki Yakura

Synthesis | 1989

Hypervalent Iodine Oxidation of p-Alkoxy- and Related Phenols: A Facile and Efficient Synthesis of p-Quinones

Yasumitsu Tamura; Takayuki Yakura; Hirofumi Tohma; Kazumi Kikuchi; Yasuyuki Kita

Chemical & Pharmaceutical Bulletin | 1997

Nonpeptide arginine vasopressin antagonists for both V1a and V2 receptors : Synthesis and pharmacological properties of 2-phenyl-4' -(2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1 -carbonyl)benzanilide derivatives

Akira Matsuhisa; Akihiro Tanaka; Kazumi Kikuchi; Yoshiaki Shimada; Takeyuki Yatsu; Isao Yanagisawa

Archive | 1991

Novel tetrahydrobenzazole derivative

Isao Yanagisawa; Toshihiro Watanabe; Kazumi Kikuchi; Akihiro Tanaka; Toshio Okazaki; Osamu Inagaki; Minoru Okada

Archive | 2003

Sodium channel inhibitor

Kazumi Kikuchi; Makoto Oku; Takeshi Hondo; Tetsuya Kimizuka; Toshihiro Watanabe; Yukinori Nagakura; Hiroshi Tomiyama; Motoharu Sonegawa; Kazuo Tokuzaki; Yoshinori Iwai

Archive | 1994