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Dive into the research topics where Kazuo Kumagai is active.

Publication


Featured researches published by Kazuo Kumagai.


FEBS Letters | 1993

Increased anti‐HIV‐1 activity of CD4 CDR3‐related synthetic peptides by scrambling and further structural modifications, including d‐isomerization and dimerization

Kazuo Kumagai; Kenzo Tokunaga; Masahiro Tsutsumi; Kazuyoshi Ikuta

We recently showed that S1, a sequence‐scrambled form of CD4 CDR3‐related synthetic peptide, has more potent inhibitory activities on HIV‐1 replication and HIV‐1‐induced syncytium formation than the original form. In this study, a series of derivatives of S1 were synthesized and their anti‐HIV‐1 activities were evaluated. A d‐isomer was as potent as S1, and a homodimer was 10‐ to 18‐fold more potent than S1. The increased antiviral activity of the dimer peptide was related to α‐helix formation, as detected by circular dichroism.


Archive | 1993

Anti-hiv peptide or peptide derivative

Kazuo Kumagai; Kazuyoshi Ikuta; Koji Ohki; Satoshi Mitsuda


Archive | 1993

Process for production of amide compounds and microorganisms for use therein

Yoshiki Takashima; Kazuo Kumagai; Satoshi Mitsuda


Archive | 1993

Verfahren zur Herstellung von Biotin A process for the production of biotin

Kazuo Kumagai; Misao Miki; Emiko Kawano; Satoshi Mitsuda


Archive | 1993

A process for the production of biotin

Kazuo Kumagai; Misao Miki; Emiko Kawano; Satoshi Mitsuda


Archive | 1993

A process for the preparation of biotin

Kazuo Kumagai; Satoshi Mitsuda; Misao Miki; Emiko Kawano


Archive | 1993

Peptide anti vih ou derives de ce peptide

Kazuo Kumagai; Kazuyoshi Ikuta; Koji Ohki; Satoshi Mitsuda


Archive | 1993

A process for the preparation of amide compounds and microorganisms for use therein

Yoshiki Takashima; Kazuo Kumagai; Satoshi Mitsuda


Archive | 1993

Verfahren zur Herstellung von Amid-Verbindungen und Mikroorganismus dafür A process for the production of amide compounds and microorganisms for

Yoshiki Takashima; Kazuo Kumagai; Satoshi Mitsuda


Collected papers from the Institute of Immunological Science Hokkaido University | 1993

Characterization of a unique scrambled peptide derived from the CD4 infection.

Kohji Ohki; Kazuo Kumagai; Satoshi Mitsuda; Toshiaki Takano; Kimura

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Satoshi Mitsuda

Tokyo Institute of Technology

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