Kazuo Yamamura

Supramolecular sensor based on SnO2 electrode modified withoctadecylsilyl monolayer having molecular binding sites

Abstract Octadecylsilyl (ODS) monolayer covalently bound onto SnO2 was found to aquire molecular binding sites via extracting out co-implanted inert guest(n-hexadecane). Intense electrochemical response of ODS/SnO 2 was found toward vit-K 1 , K 2 and E adsorbed to the molecular binding sites.

New liquid crystals having 4,4′-biphenanthryl core

Abstract 4,4′-Biphenanthryl carrying six or four long tails forms a stable thermotropic liquid crystalline mesophase, giving promises of preparing new mesogens having skewed-disc shaped core

New liquid crystalline viologens exhibiting electric stimulus-response behavior

Abstract Ca. 10 2 ∼10 4 -fold increase of electric conductivity progressed autocatalytically with new liquid crystalline viologens, 1–2, when an electric stimulus of 1–30 V was applied.

Guest selective molecular recognition by an octadecylsilyl monolayer covalently bound on an SnO2 electrode

An octadecylislyl monolayer on SnO2, which was prepared in the presence of a template guest molecule, was guest binding selective.

Kinetic study on the unfolding of apomyoglobin, detected by fluorescence- and circular dichroism-stopped-flow method

Summary Unfolding process of apoMb at acidic pH was studied by fluorescence- and CD-SF methods. In fluorescence-SF experiments, at least two relaxational decays were observed; one was less than 800 μs and the other was 1 – 100 ms. In CD-SF experiments, the relaxation occured less than 2 ms. Scheme analysis of this unfolding process is discussed.

Studies on the oxidase activity of copper(II) carboxypeptidase A

Copper(II) carboxypeptidase A catalyses the oxidation of ascorbic acid and this reaction is inhibited by α-benzylsuccinate, a known inhibitor of the thiolesterase action of the copper enzyme; the pH dependencies of kcat and kcat/Km are similar near pH 7 to those seen for the peptidase and esterase activities of native carboxypeptidase A.

Liquid crystals II. The tail design via β-oxygen atom modification for the remarkably enhanced stability of hexakis (alkanoyloxy) triphenylene mesophase

Abstract A new family of liquid crystalline compounds, 2,3,6,7,10,11-hexakis(3-oxaalkanoyloxy)triphenylene, was found to exhibit very wide mesomorphic temperature ranges, providing a promising design principle for mesogen construction, β-oxa modification of tail alkyls.

A kinetic study of the unfolding of myoglobin at low pH, monitored by absorbance and circular-dichroism stopped-flow

Abstract The unfolding of myoglobin at low pH was investigated by stopped-flow measurements monitored both by absorbance and by circular dichroism. Absorbance monitoring revealed a new, ‘fast’ relaxation process ( τ 1 2 ms ). This is accompanied by a change in circular dichroism, as in the slower of the two previously observed processes (Kihara, H. et al. (1979) Report read at the International Discussion Meeting of Protein Folding held at Regensburg, F.R.G., September 10–12, and Shen and Hermans (1972) Biochemistry 11 1836–1841).

Synthesis of a new liquid crystal with a 4,4′-biphenanthryl core

4,4′-Biphenanthryl carrying six long tails forms a stable thermotropic liquid crystalline mesophase.

Generation of Plane Chirality via Specific Host-Guest Interaction by a Macrocyclic Heterocyclophane in the Crystal Phase

Macrocyclic cyclophanes are very suitable as completely artificial host molecules for the following reasons: a) very easy preparation, b) the well-defined molecular geometry, size, or shape, c) the readily available information concerning various physicochemical properties, e.g., macroring conformation, internal rotation etc., and d) the remarkable thermal or chemical stability. Thus, the host structures can be designed so that they may have the most appropriate size, shape, and/or functionality for the specific guest recognition. Hitherto, only a very limited number of macrocyclic cyclophane-guest pairs have been studied in the crystalline state. And most of them so far known are lattice (cavity) inclusion or channel inclusion compounds (Table I).