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Keita Hamasaki

Shibaura Institute of Technology

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Bioorganic & Medicinal Chemistry | 2015

Nucleobase modified neamines with a lysine as a linker, their inhibition specificity for TAR-Tat derived from HIV-1

Ryo Inoue; Kentarou Watanabe; Toyofusa Katou; Yasunori Ikezawa; Keita Hamasaki

Nucleobase modified neamines with a lysine as the linker (NbK-neamines) were synthesized and their binding toward hairpin RNAs derived from HIV-1 activator region were studied. NbK-neamines were bind those RNAs with micro molar level of binding affinities and compete with corresponding activator peptide for TAR RNA, but not for RRE RNA. GbK-neamine denotes the highest binding affinity with TAR RNA, three to five times higher than other three NbK-neamines. GbK-neamine could be a candidate of potential inhibitor for TAR-Tat.

Bioorganic & Medicinal Chemistry | 2006

Neamine derivatives having a nucleobase with a lysine or an arginine as a linker, their synthesis and evaluation as potential inhibitors for HIV TAR-Tat

Saki Yajima; Hirohito Shionoya; Takashi Akagi; Keita Hamasaki

Tetrahedron-asymmetry | 2006

Synthesis of trehalose mimics by bismuth(III) triflate or bis(trifluoromethane)sulfonimide-catalyzed 1-C-methyl-D-hexopyranosylation

Takashi Yamanoi; Ryo Inoue; Sho Matsuda; Kaname Katsuraya; Keita Hamasaki

Tetrahedron Letters | 2006

Synthesis of aminoglycoside derivatives on a Cbz-type heavy fluorous tag

Mamoru Mizuno; Hiroharu Matsumoto; Kohtaro Goto; Keita Hamasaki

Nucleic acids symposium series (2004) | 2007

Nucleobase modified neamines, their synthesis and binding specificity for HIV TAR RNA

Kenatarou Watanabe; Toyofusa Katou; Yasunori Ikezawa; Saki Yajima; Hirohito Shionoya; Takashi Akagi; Keita Hamasaki

Nucleic acids symposium series (2004) | 2005

Amino disaccharides having an α-(1→4) or a β-(1→4) linkage, their synthesis and evaluation as a potential inhibitor for HIV-1 TAR-Tat

Takashi Iguchi; Hirohumi Ishikawa; Hiroharu Matumoto; Mamoru Mizuno; Kohtaro Goto; Keita Hamasaki

Journal of Physiological Anthropology and Applied Human Science | 2005

Techniques of SNP Genotyping and Remote Sensing Applied for Elucidation of the Contribution of Polygene and Environmental Factors to Inter-individual Variation in Skin Pigmentation Phenotype

Sumiko Anno; Susumu Kudo; Keita Hamasaki; Kazunari Matsumura; Takushi Yamamoto; Koretsugu Ogata

Chemistry Letters | 2018

Hydrophobic Association of a Side Chains Induces Reversible Helix Folding in a Dual Aromatic Ring Tagged Short Peptide

Ryusuke Tsuchie; Mayu Shimosato; Keita Hamasaki

Transactions of the Japan Society of Mechanical Engineers. B | 2012

Analysis of GPI-AP diffusion on plasma membrane of endothelial cell using photochromic fluorescent protein

Naoto Kawasaki; Tomoya Shimada; Takekazu Fukui; Keita Hamasaki; Susumu Kudo

Glycoconjugate Jornal | 2007

Synthesis of non-reducing disaccharides by the bismuth(III) triflate-catalyzed glycosidation

Ryo Inoue; Matsuda Sho; Akihiko Yoshida; Takashi Yamanoi; Keita Hamasaki

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