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Keith Allan Menear

University of Leicester

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Publication

Featured researches published by Keith Allan Menear.

Journal of The Chemical Society, Chemical Communications | 1984

An intramolecular Diels–Alder approach to forskolin

Paul R. Jenkins; Keith Allan Menear; Paul Barraclough; Malcolm S. Nobbs

A Diels–Alder route to two tricyclic lactoes with the same relative stereochemistry as C-1 and C-10 in forskolin is described.

Tetrahedron Letters | 1986

Mechanistic rationalization of an apparently non-stereospecific intramolecular Diels-Alder reaction

Philip Magnus; Clive Victor Walker; Paul R. Jenkins; Keith Allan Menear

Summary The loss of dienophile stereochemistry in the conversion of 1 / 4 into 3 / 6 is shown to result from epimerization α − to the lactone carbonyl via 9 .

Archive | 2005

4-heteroarymethyl substituted phthalazinone derivatives

Muhammad Hashim Javaid; Keith Allan Menear; Sylvie Gomez; Marc Geoffrey Hummersone; Niall Morrisson Barr Martin; Graeme Cameron Murray Smith; Xiao Ling Fan Cockcroft; Frank Kerrigan

Archive | 2007

2-methylmorpholine pyrido-,pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors

Heather Mary Ellen Duggan; Frederic Leroux; Karine Malagu; Niall Morrisson Barr Martin; Keith Allan Menear; Graeme Cameron Murray Smith

Archive | 2006

Hydrazinomethyl, hydr zonomethyl and 5-membered heterocylic compounds which act as mtor inhibitors and their use as anti cancer agents

Marc Geoffrey Hummersone; Sylvie Gomez; Keith Allan Menear; Xiao-Ling Fan Cockcroft; Graeme Cameron Murray Smith

Archive | 2003

Pyranones useful as atm inhibitors

Graeme Cameron Murray Smith; Niall Morrison Barr Martin; Stephen Philip Jackson; Mark J. O'Connor; Alan Y. K. KuDOS Pharmaceuticals Ltd Lau; Xiao-Ling Fan Cockcroft; Ian Timothy Williams Matthews; Keith Allan Menear; Laurent Jean Martin Rigoreau; Marc Geoffrey Hummersone; Roger John Griffin

Archive | 2006

mTOR inhibitor compounds

Marc Geoffrey Hummersone; Sylvie Gomez; Keith Allan Menear; Xiao-Ling Fan Cockcroft; Graeme Cameron Murray Smith

Archive | 1996

Tetrahydroquinoline inhibitors of trypsin and thrombin

Mark C. Allen; Derek E. Brundish; Paul Ian Butler; Joseph Dawson Fullerton; Judy Hayler; Peter Herold; Peter Kane; Grand Darren Mark Le; Keith Allan Menear; Clive Victor Walker

Archive | 2008

Phthalazinone derivatives and their use as medicament to treat cancer

Keith Allan Menear; Marc Geoffrey Hummersone; Sylvie Gomez; Muhammad Hashim Javaid; Niall Morrison Barr Martin

Archive | 2007

2 -oxybenzamide derivatives as parp inhibitors

Muhammad Hashim Javaid; Sylvie Gomez; Xiao-Ling Fan Cockcroft; Keith Allan Menear; Niall Morrison Barr Martin

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Collaboration

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Xiao-Ling Fan Cockcroft

Novartis

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Graeme Cameron Murray Smith

University of Cambridge

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Niall Morrison Barr Martin

Cameron International

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Sylvie Gomez

Novartis

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Roger John Griffin

University of Newcastle

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Clive Victor Walker

Indiana University Bloomington

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Laurent Jean Martin Rigoreau

University of Newcastle

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Grand Darren Mark Le

Novartis

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Muhammad Hashim Javaid

AstraZeneca

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Henri Mattes

Novartis

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