Kenichiro Mori

Chlorovulones, new halogenated marine prostanoids with an antitumor activity from the stolonifer clavularia viridis Quoy and Gaimard

Abstract New halogenated marine prostanoids, chlorovulone I, II and III were isolated from the stolonifer Clavularia viridis Quoy and Gaimard. The structure elucidation and the antitumor activity of chlorovulones were described.

Stolonidiol, a new marine diterpenoid with a strong cytotoxic activity from the Japanese soft coral

Abstract Structures of stolonidiol ( 1 ) and stolonidiol monoacetate ( 2 ), new marine diterpenoids with a strong cytotoxic activity from the Japanese soft coral Clavularia sp., were established by means of spectroscopic analyses, chemical reactions, and X-ray crystallographic analysis.

Bromovulone I and iodovulone I, unprecedented brominated and iodinated marine prostanoids with antitumour activity isolated from the Japanese stolonifer Clavularia viridis Quoy and Gaimard

The novel brominated and iodinated antitumour marine prostanoids bromovulone I and iodovulone I were isolated from the Japanese stolonifer Clavularia viridis Quoy and Gaimard; their structures were determined on the basis of spectroscopic data.

Analysis of alkyltrimethyl- and dialkyldimethylammonium compounds by gas chromatography

Abstract A method for the determination of long-chain alkyltrimethylammonium chlorides (I–VII) and dialkyldimethylammonium chlorides (VIII, IX) by gas chromatography has been developed. The Hofmann degradation of I–IX with potassium tert.butoxide in benzene-dimethyl sulphoxide (8:2) under reflux for 30 min gave quantitatively the corresponding 1-olefin. The 1-olefins obtained were measured by gas chromatography on a 5% SE-30 column. The proposed method could be applied to the analysis of these compounds in household products such as hair rinses, fabric softeners and antistatic aerosols.

Gas chromatographic method for the determination of 3-(trimethoxysilyl)propyloctadecyldimethylammonium chloride

Abstract A sanitary finishing agent, 3-(trimethoxysilyl)propyloctadecyldimethylammonium chloride (I), was easily degraded with potassium tert.-butoxide in benzene—dimethyl sulphoxide (8:2) under mild conditions to yield 1-octadecene and octadecyldimethylamine in the ratio 5:1. The volatile 1-octadecene was detected on a 5% SE-30 column by gas chromatography with a hydrogen flame ionization detector. The calibration curve was linear at levels ranging from 40 to 200 ppm of compound I. The proposed method was applied to the determination of compound I in commercial textile products.

Determination of Methanol in Aerosol Products Containing Propellant.

According to the official analytical method of methanol in commercial aerosol products, the concentration of methanol in their propelled solution was limited to less than 5%. The propelled solution was sampled by propelling aerosol into a flask for the evacuation of the propellant only. There was the possibility of occurrence of errors due to flying nebulized methanol in the procedure of propelling, or due to the high volume of dissolving propellant in the propelled solution. In this paper, after making some test aerosol products, the possibility of occurrence of error was discussed. The recoveries of methanol in the test aerosol products containing the ratio of 5% methanol/ethanol solution and isobutane by weight of 5 : 5, 4 : 6, 3 : 7 were high yields ranging from 97.5 to 99.2%. But those of 2 : 8 and 1 : 9 were 94.4% and 80.3% respectively due to the flying nebulized methanol. The detective yield of methanol in the propelled solution from the test aerosol products in the ratio of 3 : 7, after weighing the propelled solution by pouring it into a volumetric flask, with the propellant kept inside, was only 67.3%. The problem of dissolving propellant was solved by freeing the propellant while swinging the propelled solution flask on a water bath (20°C) within a tiny zeolite and weighing the propelled solution using a 1 mm i. d. tip dropping pipet. As a result of this experiment, it is suggested that the determination of methanol by the official analytical method may not be achieved in an aerosol containing high percentage of propellant.