Kenny B. Lipkowitz

Conformational analysis of the covalent Pirkle chiral stationary phases

Abstract The multidimensional potential energy surface for a model Pirkle chiral stationary phase is computed with MM2. Five minimum energy conformations are located, the minimum energy reaction pathway between the three lowest energy forms is described and the ability of these chiral phases to act as templates is discussed.

The synthesis of N-substituted tetrahydropyridines using the hetero-cope rearrangement

Abstract Several imines have been prepared from methacrolein dimer. Thermal rearrangement of these molecules resulted in the formation of N-substituted tetrahydropyridines.