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Ki Dong Koo

Korea Institute of Science and Technology

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Featured researches published by Ki Dong Koo.

Bioorganic & Medicinal Chemistry Letters | 2000

Synthesis and biological properties of new 1β-methylcarbapenems having tetrazolothioether moiety

Kye Jung Shin; Ki Dong Koo; Kyung Ho Yoo; Dong Chan Kim; Dong Jin Kim; Sang Woo Park

The synthesis and biological activities of a series of new 1beta-methylcarbapenems 1a-l having tetrazolothioether moiety at C-5 position of pyrrolidine were described. Among these compounds, 1c showed the most potent antibacterial activity and advanced pharmacokinetics compared with imipenem and meropenem.

Bioorganic & Medicinal Chemistry Letters | 2001

Synthesis and biological properties of new 1β-methylcarbapenems containing heteroaromatic thioether moiety

Kye Jung Shin; Ki Dong Koo; Kyung Ho Yoo; Yong Koo Kang; Sang Woo Park; Dong Jin Kim

The synthesis and biological activities of a series of new 1beta-methylcarbapenems 1a-h having heteroaromatic thioether moiety at C-5 position of pyrrolidine were described. Among these compounds, 1,2,3-thiadiazole derivative 1h showed the most potent antibacterial activity and advanced pharmacokinetics in comparison with meropenem.

Archive | 2004

Novel inhibitors of dpp-iv, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent

Chang-Seok Lee; Ki Dong Koo; Jong Sung Koh; Sungsub Kim; Dong-Myung Kim; Min-Jung Kim; Bongchan Kim; Suk Kyoon Yoon; Sungji Kim; Hyeon Joo Yim; Gwong-Cheung Hur; Sun Hwa Lee; Hee Oon Han; Kyoung-Hee Kim; Geun Tae Kim; Oh Hwan Kwon; Tae-Sik Kwon; Hee Bong Lee; Hee-Kyung Chung; Misun Kim; Dongchul Lim; Yeon Chul Kim; Sungho Kim

Archive | 2006

Dipeptidyl Peptidase-IV inhibiting compounds, method of preparing the same, and pharmaceutical compositions containing the same as an active agent

Chang-Seok Lee; Jong Sung Koh; Ki Dong Koo; Geun Tae Kim; Kyoung-Hee Kim; Sang Yong Hong; Sungsub Kim; Min Jung Kim; Hyeon Joo Yim; Dongchul Lim; Hye Jin Kim; Hee Oon Han; Seong Cheol Bu; Oh Hwan Kwon; Sung Ho Kim; Gwong-Cheung Hur; Ji Young Kim; Zi-Ho Yeom; Dong-Jun Yeo

Bioorganic & Medicinal Chemistry Letters | 2007

Design and synthesis of oxime ethers of α-acyl-β-phenylpropanoic acids as PPAR dual agonists

Hee Oon Han; Seung Hae Kim; Kyoung-Hee Kim; Gwong-Cheung Hur; Hyeon Joo Yim; Hee-Kyung Chung; Sung Ho Woo; Ki Dong Koo; Chang-Seok Lee; Jong Sung Koh; Geun Tae Kim

Bioorganic & Medicinal Chemistry Letters | 2008

Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives.

Heuisul Park; Kyeongsik Min; Hyo-Shin Kwak; Ki Dong Koo; Dongchul Lim; Sangwon Seo; Jae-Ung Choi; Bettina Platt; Deog-Young Choi

Archive | 2008

NOVEL DIPEPTIDYL-PEPTIDASE-IV INHIBITORS

Ki Dong Koo; Hyejin Jung; Chang-Seok Lee; In Sang Lee; Dong Jun Yeo; Oh Hwan Kwon; Kyoung-Hee Kim; Dongchul Lim; Youn Hoa Kim; Minsun Chang; Ji Young Kim; Jong Sung Koh

Archive | 2006

Novel compounds as agonist for ppar gamma and ppar alpha, method for preparation of the same, and pharmaceutical composition containing the same

Geun Tae Kim; Hee Oon Han; Jong Sung Koh; Seung Hae Kim; Kyoung-Hee Kim; Hee-Kyung Chung; Ok Ku Park; Sang Kweon Jeon; Sung Ho Woo; Hyeon Joo Yim; Gwong-Cheung Hur; Sung Woon Hong; Ki Dong Koo; Chang-Seok Lee; Min Sun Chang; Sunyoung Koo; Hyun Woo Joo; Jeong Uk Song; Sang Pil Moon; Song-Mi-A

Bioorganic & Medicinal Chemistry Letters | 2007

Synthesis, SAR, and X-ray structure of novel potent DPPIV inhibitors: oxadiazolyl ketones.

Ki Dong Koo; Min-Jung Kim; Sungsub Kim; Kyoung-Hee Kim; Sang Yong Hong; Gwong-Cheung Hur; Hyeon Joo Yim; Geun Tae Kim; Hee Oon Han; O. Hwan Kwon; Tae Sik Kwon; Jong Sung Koh; Chang-Seok Lee

Archive | 2009