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Kikuchi Shintaro

Takeda Pharmaceutical Company

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Publication

Featured researches published by Kikuchi Shintaro.

European Journal of Pharmacology | 1981

Coronary vasoconstriction and PGI2 release by leukotrienes in isolated guinea pig hearts

Zen-ichi Terashita; Hiroshi Fukui; Minoru Hirata; Shinjo Terao; Shigenori Ohkawa; Kokei Nishikawa; Kikuchi Shintaro

In isolated, perfused guinea pig hearts, leuokotrienes C4 and D4 (0.1–100 ng) dose-dependently decreased coronary flow rate and left ventricular systolic pressure. The leukotrienes (10–100 ng) released prostacyclin, but not thromboxane A2, from the heart. In isolated atria, they (10−8–10−6 M) showed slight positive inotropism. Thus, it is concluded that leukotrienes C4 and D4 are potent coronary vasoconstrictors, and might play a role in coronary vasospasm during cardiac anaphylaxis.

Archive | 1975

7-(HYDROXYPHENYL)PYRIDO ECKIGE KLAMMER AUF 3,4-D ECKIGE KLAMMER ZU PYRIDAZINE UND VERFAHREN ZU IHRER HERSTELLUNG

Yurugi Shojiro; Kikuchi Shintaro

Archive | 1973

NEUE PYRIMIDOPYRIMIDINDERIVATE UND VERFAHREN ZU IHRER HERSTELLUNG

Yurugi Shojiro; Kikuchi Shintaro

Archive | 1973

PYRIDO ECKIGE KLAMMER AUF 3,4-D ECKIGE KLAMMER ZU PYRIDAZINDERIVATE UND VERFAHREN ZU IHRER HERSTELLUNG

Yurugi Shojiro; Kikuchi Shintaro; Oka Yoshikazu; Miyake Akio; Ito Katsumi; Omura Kiyoshi

Archive | 1980

ANALOGIFREMGANGSMAATE TIL FREMSTILLING AV DIURETISK VIRKSOMME 8-ALKYLPYRIDO(3,4-D)PYRIDAZINER

Yurugi Shojiro; Kikuchi Shintaro

Archive | 1979

Analogifremgangsmåde til fremstilling af pyridopyridazinderivater eller salte deraf.

Yurugi Shijiro; Kikuchi Shintaro; Oka Yoshikazu; Miyake Akio; Ito Katsumi; Omura Kiyoshi

Archive | 1978

ADSORPSJONSMIDDEL FOR BRUK I KUNSTIG NYRE AV RESIRKULASJONSTYPEN

Hori Masatake; Kikuchi Shintaro

Archive | 1977

ANALOGIFREMGANGSM}TE TIL FREMSTILLING AV DIURETISK VIRKSOMME PYRIDO (3,4-D)PYRIDAZINDERIVATER

Yurugi Shojiro; Kikuchi Shintaro; Oka Yoshikazu; Miyake Akio; Ito Katsumi; Omura Kiyoshi

Archive | 1976

Analogifremgangsmåde til fremstilling af 8-alkylpyrido/3,4-d/-pyridaziner eller farmaceutisk acceptable salte deraf.

Yurugi Shojiro; Kikuchi Shintaro

Archive | 1976

Analogifremgangsmåde til fremstilling af 7-(hydroxyfenyl)-pyrido/3,4-d/-pyridaziner eller salte deraf.

Yurugi Shojiro; Kikuchi Shintaro

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Yurugi Shojiro

Takeda Pharmaceutical Company

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Oka Yoshikazu

Takeda Pharmaceutical Company

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Hori Masatake

Takeda Pharmaceutical Company

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Hiroshi Fukui

Takeda Pharmaceutical Company

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Kokei Nishikawa

Takeda Pharmaceutical Company

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Minoru Hirata

Takeda Pharmaceutical Company

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Shigenori Ohkawa

Takeda Pharmaceutical Company

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Shinjo Terao

Takeda Pharmaceutical Company

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Zen-ichi Terashita

Takeda Pharmaceutical Company

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