Kim Ht

Effects of zonisamide on isolated head tremor

Background and purpose:  The medical treatment available for patients with essential tremor (ET) is often inadequate. Furthermore, the efficacy of the medical treatments currently available for patients with ET of cranial nerve areas is less satisfactory than that of the medical treatments available for patients with ET involving the upper extremities. This pilot study was performed to evaluate whether zonisamide (ZNS) is effective in the treatment of patients with isolated head tremor.

Microbleeds and free active MMP-9 are independent risk factors for neurological deterioration in acute lacunar stroke.

Background and purpose:  In this prospective study, we evaluated mutual relationships amongst microbleeds, matrix metalloproteinase‐9 (MMP‐9) and neurological deterioration in patients with their first acute lacunar stroke.