Kimihiro Watanabe
Hoffmann-La Roche
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Publication
Featured researches published by Kimihiro Watanabe.
The Journal of Antibiotics | 1983
Kazuteru Yokose; Kiyoshi Ogawa; Takashi Sano; Kimihiro Watanabe; Hiromi B. Maruyama; Yasuji Suhara
Trestatin complex which exhibited a potent inhibitory activity on various alpha-amylases has been isolated from the culture filtrate of Streptomyces dimorphogenes nov. sp. NR-320-OM7HB. Three major components, trestatins A, B and C, have been purified by adsorption and ion-exchange chromatography. Their spectral and chemical properties suggested that trestatins were novel basic oligosaccharide homologues each characterized by the possession of a trehalose moiety at the non-reducing end of the molecule.
Antimicrobial Agents and Chemotherapy | 1981
Kimihiro Watanabe; Junko Watanabe; Sayoko Kuramitsu; Hiromi B. Maruyama
Representative polyethers of each group in Westleys classification and related ionophore antibiotics were examined for in vitro activity against 25 anaerobic strains. Lasalocid (X-537A) and nigericin were found to have activity comparable in potency to some leading antianaerobe antibiotics, newer cephalosporins and nitroimidazoles, with a different spectrum as revealed by a spectral comparison. A strict relationship between their antianaerobe activity and either their structural features or cation transporting properties was not apparent.
The Journal of Antibiotics | 1994
Shoichi Ohshima; Mieko Yanagisawa; Akira Katoh; Tosihiko Fujii; Takashi Sano; Shoko Matsukuma; Tamotsu Furumai; Morio Fujiu; Kimihiro Watanabe; Kazuteru Yokose; Mikio Arisawa; Toru Okuda
Archive | 1979
Yasuji Suhara; Kiyoshi Ogawa; Kazuteru Yokose; Kimihiro Watanabe
The Journal of Antibiotics | 1992
Shoko Matsukuma; Tatsuo Ohtsuka; Hiromichi Kotaki; Haruyoshi Shirai; Takashi Sano; Kimihiro Watanabe; Noboru Nakayama; Yoshiko Itezono; Morio Fujiu; Nobuo Shimma; Kazuteru Yokose; Toru Okuda
The Journal of Antibiotics | 1983
Kimihiro Watanabe; Toru Okuda; Kazuteru Yokose; Tamotsu Furumai; Hiromi B. Maruyama
Archive | 1978
Yasuji Suhara; Hiromi B. Maruyama; Toyoaki Sawada; Mayumi Ogawa; Kazuteru Yokose; Morio Fujiu; Kimihiro Watanabe
The Journal of Antibiotics | 1994
Mieko Yanagisawa; Akiko Sakal; Kazunori Adachi; Takashi Sano; Kimihiro Watanabe; Yutaka Tanaka; Toru Okuda
Applied and Environmental Microbiology | 1983
Toyoaki Sawada; Mayumi Ogawa; Rieko Ninomiya; Kazuteru Yokose; Morio Fujiu; Kimihiro Watanabe; Yasuji Suhara; Hiromi B. Maruyama
Archive | 1978
Yasuji Suhara; Hiromi B. Maruyama; Toyoaki Sawada; Mayumi Ogawa; Kazuteru Yokose; Morio Fujiu; Kimihiro Watanabe
