Kimio Shindo

A convenient, one-pot synthesis of azulenes having versatile functional groups by the reaction of 2H-cyclohepta[b]furan-2-ones with furan derivatives

2-Acylmethyl- and 2-methoxycarbonylmethylazulene derivatives having versatile functional groups in the side chain, are synthesized in one-pot by the reaction of 2H-cyclohepta [b] furan-2-ones with furans on heating at 160-190 ° C in aprotic solvent

One-pot synthesis of tropocoronands having heteroatoms in linker chains and related podands

Treatment of benzo[b]cyclohepta[e][1,4]oxazine (4) with 1.2 equiv. of dipropylenetriamine (5a) in ethanol at 80 °C gave 6,7,8,9,11,12,13,20,- 21,22,23,25,26,27-tetradecahydrodicyclohepta[b,m][1,4,8,12,15,19]hexa- azacyclodocosine (7a). Similar reactions of (4) with N,N-bis(3-amino- propyl)methylamine (5b), bis(3-aminopropyl) ether (5c), 1,2-bis(2-amino- ethoxy)ethane (6b), and cystamine (6c) afforded similar tropocoronands (7b, 7c, 8a, and 8b), respectively, while the reactions of (4) with an excess of these amines gave the corresponding tropopodands (11a, 11b, 11c, 12a, and 12b). The reaction of (4) with diethylenetriamine (6a) yielded tricyclic compound (10) via bicyclic pyrazino compound (9). A single-crystal X-ray diffraction analysis of the nickel(II)-complex (13) obtained from (7a) was made