Kirit H. Patel

Cu(N-heterocyclic carbene)chloride: an efficient catalyst for multicomponent click reaction for the synthesis of 1,2,3-triazoles in water at room temperature

A novel water soluble copper(N-heterocyclic carbene)chloride [Cu(NHC)Cl] complex of vitamin B1 was synthesized and characterized by EDX, FT-IR and NMR spectroscopy. It was employed for three component click reaction of benzyl chlorides 1a–e, alkynes 2a–c and sodium azide 3 in water at room temperature. All the synthesized compounds 4a–o were characterized by elemental analysis, IR, and 1HNMR spectroscopy. The catalyst was easy to prepare, very versatile, reusable and was found to be highly active at low catalyst loading for a variety of substrates with a varied nature of substituents.

Palladium N-heterocyclic carbene catalyzed regioselective C–H halogenation of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones using N-halosuccinimides (NXS)

A novel palladium N-heterocyclic carbene [Pd(NHC)Cl2] complex of vitamin B1 was synthesized and characterized by 1H NMR, EDX, FT-IR and UV–visible spectroscopy. The complex was used as a catalyst for regioselective ortho-C–H chlorination/bromination of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones via C–H bond activation utilizing Ag2O as the effective terminal additive. The catalyst was easy to prepare, efficient and found to be highly regioselective, affording the target products in moderate to excellent yields.

SYNTHESIS, CHARACTERIZATION, THERMAL PROPERTIES AND ANTIMICROBIAL ACTIVITY OF ACRYLIC COPOLYMERS DERIVED FROM 2,4-DICHLOROPHENYL ACRYLATE

ABSTRACT Copolymer of monomer 2,4-dichlorophenylacrylate (2,4-DCPA) and methylmethacrylate (MMA) were synthesized with different monomer feed ratio using dimethylformamide (DMF) as a solvent and 2,2’-azobisisobutyronitrile (AIBN) as an initiator at 70 oC. The copolymers were characterized by IR-Spectroscopy and copolymer composition was determined with UV-Spectroscopy. The linearization method of Fineman Ross (F-R) and Kelen Tudos (K-T) were used to obtain the monomer reactivity ratios. Thermal analyses of polymer were carried out in nitrogen atmosphere thermal gravimetric analyses (TGA) and differential thermal analyses (DTA). The molecular weight and intrinsic viscosity were determined by vapor pressure osmometry (VPO). The homo and copolymers were tested for their antimicrobial properties against selected microorganisms. Key words: Copolymer / Thermal Analysis / Reactivity Ratio / Antimicrobial Activity INTRODUCTION Copolymer is the most successful and powerful method for effecting systematic change in polymer [1]. Phenyl acrylate polymers are relatively newly developed materials compared to the commercial polymer such as vinylics. Acrylate is considered as reactive monomers primarily because of the presence of aromatic ring [2]. Choudhary Veena and coworkers [3-5] prepared copolymer of methyl methacrylate (MMA) with a variety of vinyl monomers. Strum [6] reported about thirty eight ester useful as commercial bactericides and fungicides. Plunder and coworkers [7] synthesized acrylics ester, useful as biocides by reacting pentachloro phenol,

2,4‐Dichlorophenyl Acrylate/8‐Quinolinyl Methacrylate Copolymers: Ion‐Exchange Study

The chelating ion‐exchange properties of the 2,4‐dichlorophenyl acrylate (2,4‐DCPA)/8‐quinolinyl methacrylate (8‐QMA) copolymers, synthesized using different monomer feed ratios, were investigated by the batch equilibrium method. Five metal ions Cu+2, Ni+2, Co+2, Zn+2, and Fe+3 were used to evaluate the cation‐exchanger capability of 2,4‐DCPA‐co‐8‐QMA copolymers. The ion‐exchange study was carried out for three different experimental variables viz., pH of the aqueous medium, ionic strength of electrolyte and shaking time. It was observed that due to the presence of a pendant ester‐bound quinolinyl group, the copolymers are better suited as cation exchangers.

Modification of sodium salt of partially carboxymethylated tamarind kernel powder through grafting with acrylonitrile: Synthesis, characterization and swelling behavior

A graft copolymer of polyacrylonitrile (PAN) with sodium salt of partially carboxymethylated tamarind kernel powder (Na-PCMTKP,

Development and Applications of Novel Acrylic Copolymers

\overline {DS} = 0.15

Synthesis, characterization, in silico molecular docking study and biological evaluation of a 5-(phenylthio) pyrazole based polyhydroquinoline core moiety

) was synthesized by using ceric ammonium nitrate (CAN) as a redox initiator in an aqueous medium. The optimum reaction conditions for affording maximum percentage of grafting were established by successively varying reaction conditions such as concentrations of nitric acid, CAN, monomer (AN) as well as reaction time, temperature and amount of substrate. The influence of these reaction conditions on the grafting yields was discussed. The kinetic scheme of free radical graft copolymerization was proposed and the experimental results were found to agree very well with the proposed kinetic scheme. The graft copolymer (Na-PCMTKP-g-PAN, percentage of grafting G = 413.76% and percentage of grafting efficiency GE = 96.48%) sample synthesized under the established optimized reaction conditions was hydrolyzed by 0.7 mol·L−1 NaOH solution at 90–95°-C to yield the superabsorbent hydrogel, H-Na-PCMTKP-g-PAN. The swelling behavior of the hydrogel was studied by carrying out its absorbency measurements in low conductivity water, 0.15 mol·L−1 salt (NaCl, CaCl2 and AlCl3) solutions and simulated urine (SU) solution at different timings. FTIR, TGA and SEM techniques were used to characterize the products.

Palladium N-heterocyclic carbene catalyzed expected and unexpected C–C and C–N functionalization reactions of 1-aryl-3-methyl-1H-pyrazol-5(4H)-ones

Some copolymers of 2,4-dichlorophenyl acrylate (2,4-DCPA) with styrene (St) of different feed compositions were prepared by free radical polymerization technique using 2,2′-azobisisobutyronitrile (AIBN) as an initiator, and the copolymers were characterized by IR spectroscopy. The copolymer composition obtained by UV-spectra led to determination of reactivity ratio by employing Fineman-Ross (F-R) and Kelen-Tudos (K-T) methods. Average molecular weight, as well as intrinsic viscosity, was obtained by vapor pressure osmometry (VPO) and Ubbleholde viscometer. Thermo gravimetric analysis (TGA) and differential thermal analysis (DTA) of copolymers were carried out under nitrogen atmosphere. Antimicrobial effects of the homo and copolymers were also investigated against various microorganisms such as bacteria, fungi and yeasts.