Kiyomi Kuba
Saitama Medical University
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Publication
Featured researches published by Kiyomi Kuba.
Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2015
Kiyomi Kuba; Hitoshi Inoue; Takahiro Hayashi; Satoko Matsumura; Kazuhiko Minami; Humihiko Takajo; Kei Morita; Mitsuhiko Nakahira; Masashi Sugasawa
Sarcomas of the larynx are uncommon tumors, and osteosarcoma is the rarest. Only 24 cases of osteosarcoma of the larynx have been reported. The only case reported in Asia was from Thailand in 1981.
Head and Neck-journal for The Sciences and Specialties of The Head and Neck | 2018
Yasunao Kogashiwa; Hitoshi Inoue; Kiyomi Kuba; Ryuichiro Araki; Masanori Yasuda; Mitsuhiko Nakahira; Masashi Sugasawa
Cetuximab combined with chemoradiotherapy chemotherapy is the standard therapy for recurrent/metastatic head and neck squamous cell carcinoma (HNSCC). However, survival benefit is limited. The purpose of this study was to investigate the expression of epiregulin (EREG) and amphiregulin (AREG), as predictive prognostic markers for the efficacy of cetuximab combined with chemotherapy in R/M HNSCC.
Case reports in otolaryngology | 2017
Mitsuhiko Nakahira; Kiyomi Kuba; Satoko Matsumura; Masashi Sugasawa
Objective Two patients with primary small cell carcinoma (SmCC) of the hypopharynx, an extremely rare site for the occurrence of SmCC, are reported and nine additional well-documented cases are reviewed. Methods Case report and review of the literature concerning primary SmCC of the hypopharynx. Results On the final analysis, we reviewed eleven cases of primary SmCC of the hypopharynx. The tumors contained mixed elements of SmCC and squamous cell carcinoma (SCC) in six (55%) of eleven patients. Out of eleven patients, two patients had distant metastasis at the initial presentation. Even though nine patients presented with locoregional disease, development of distant metastasis after treatment was seen in five patients (56%), whereas there was no report of treatment failure on the primary site. To achieve more than two-year survival, patients should have received more than 4 cycles of chemotherapy. Conclusion We report two cases of primary SmCC of the hypopharynx with a review of the literature. In more than half of the cases, combined carcinomas with SCC are seen. Because this tumor has a strong propensity for distant metastasis even in patients with clinically localized tumor, new powerful systemic agents should be explored.
European Archives of Oto-rhino-laryngology | 2014
Mitsuhiko Nakahira; Naoko Saito; Hiroshi Yamaguchi; Kiyomi Kuba; Masashi Sugasawa
European Archives of Oto-rhino-laryngology | 2016
Mitsuhiko Nakahira; Masashi Sugasawa; Satoko Matsumura; Kiyomi Kuba; Susumu Ohba; Takahiro Hayashi; Kazuhiko Minami; Yasuhiro Ebihara; Yasunao Kogashiwa
Nippon Jibiinkoka Gakkai Kaiho | 2013
Kiyomi Kuba; Hitoshi Inoue; Satoko Matsumura; Kazuhiko Minami; Fumihiko Takajo; Kei Morita; Mitsuhiko Nakahira; Masashi Sugasawa
Practica oto-rhino-laryngologica | 2018
Kazuhiko Minami; Kiyomi Kuba; Hitoshi Inoue; Masashi Sugasawa
Journal of Japan Society for Head and Neck Surgery | 2018
Kazuhiko Minami; Susumu Oba; Kiyomi Kuba; Hitoshi Inoue; Yasunao Kogashiwa; Yasuhiro Ebihara; Mitsuhiko Nakahira; Masashi Sugasawa
Cancer Research | 2018
Yasunao Kogashiwa; Hitoshi Inoue; Kiyomi Kuba; Masanori Yasuda; Mitsuhiko Nakahira; Masashi Sugasawa
Toukeibu Gan | 2017
Susumu Ohba; Yasunao Kogashiwa; Hitoshi Inoue; Kiyomi Kuba; Kazuhiko Minami; Yasuhiro Ebihara; Mitsuhiko Nakahira; Masashi Sugasawa
