Kiyoo Kamikawa

Analysis of lateral column units related to vesical reflexes.

Abstract Our aim was to confirm with electrophysiological techniques the concept previously based on anatomical studies that ascending fibers related to bladder sensation project to bulbar levels via a tract in the lateral funiculus, designated the “sacro-bulbar tract”. Thirty-two units, discharge patterns of which were altered during reflex “isovolumetric” vesical contraction, were recorded at the upper lumbar level of this tract. Unitary discharge was induced cystometrically in decerebrate cats. Fifteen units were accelerated during vesical contraction, and seventeen were inhibited. The injection of a barbiturate to suppress supraspinal influences on lateral column units, with the simultaneous intravesical infusion of pilocarpine to evoke a drug-induced vesical contraction, proved useful in assessing the centripetal or centrifugal nature of the responses.