Kiyoshi Mizumoto

Bone disorder following partial and total gastrectomy with reference to bone mineral content

To study post-gastrectomy metabolic bone disorders, we measured the radial bone mineral content (BMC), serum levels of calcium, inorganic phosphorus, alkaline phosphatase, and 25-hydroxyvitamin D(25-OH-D) in 59 patients with partial- and 39 patients with total gastrectomy. Total gastrectomy patients manifested a higher incidence of decreased BMC levels than did partial gastrectomy patients (56 per centvs. 25 per cent). Patients subjected to the Billroth II procedure, especially females, manifested abnormally low BMC values. The decline in BMC was age-related; it was pronounced in females. At 10 years postoperatively, many of the partial gastrectomy patients manifested markedly low BMC levels; in totally gastrectomized patients this finding was made at less than 5 years postoperatively. Approximately 30 per cent of our patients showed abnormalities in serum minerals, alkaline phosphatase or 25-OH-D.

Pulmonary function before and after abdominal surgery in the aged

AbstractIn patients 70 years or older, pulmonary function tests were performed before and after abdominal surgery to correlated the results with the development of postoperative pulmonary complications which developed in 48% of these patients, compared to 15% in the control group. To predict the development of PPC, preoperative analysis of the flow-volume curve is useful and

Carcinosarcoma of the esophagus—A case report

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Significance of proximal gastrectomy for carcinoma of the upper portion of the stomach, with special reference to operative curability and postoperative gastrointestinal hormones.

vital capacity is a valuable parameter for the analysis of the flow-volume curve. Postoperatively, pulmonary function was reduced and there was a delay in the restoration of pulmonary function in cases with postoperative pulmonary complications. The administration of appropriate analgesics may be useful to improve postoperative ventilatory disturbances.

A Case of Gastric Cancer in the Reconstructed Gastric Tube after Radical Resection for Esophageal Cancer.

Serum zinc and copper levels were evaluated in patients with gastric cancer who had undergone gastrectomy. These patients were divided into two age categories; namely, the aged group, comprising 39 patients over the age of 70 years, and the younger group, comprising 23 patients younger than 50 years. The data before and after surgery were compared between the two groups. Serum zinc levels in the aged group were significantly lower than those in the younger group, both before and after surgery. Serum copper levels, however, did not differ significantly between the two groups. The serum Cu/Zn ratio was also analyzed according to the histological stages of cancer (stages I to IV), and compared between the two ageclassified groups. The aged group showed a higher Cu/Zn ratio at all stages, whereas in the younger group, the ratio was significantly higher at stage IV than in the earlier stages. Preoperative serum zinc, copper, and the Cu/Zn ratio were studied in relation to the complication of anastomotic leak after surgery. The Cu/Zn ratio in the aged patients with this complication was significantly higher than that in the aged patients without it. These results suggest that the Cu/Zn ratio may be an important factor in determining nutritional parameters in the aged.

Familial Occurrence of the Currarino Triad : A Report of 3 Cases

We report a case of true esophageal carcinosarcoma, in which well-differentiated squamous cell carcinom and spindle-shaped cell sarcoma were intermingled in the primary and metastatic lesions.

A Case of Gastric Cancer with Calcification.

70歳以上の高齢者の開腹手術前後に各種肺機能検査を施行し, 術後肺合併症との相関を検討した.高齢者の術後肺合併症の発生頻度は48%と高率であった.高齢者では, 術前より多彩な肺の病変を右し, とくに慢性閉塞性肺疾患を併存する例では, 術後肺合併症発生率が高く, かかる症例に対してはFlow-volume曲線は有用な検査法である.術後では, 早期の換気能障害は顕著であり, poor risk例および肺合併症合併例では術前値への回復が非常に遅延した.術後のhypoxemiaは無気肺に起因するshuntが主要因と思われる.