Kiyoshi Nakayasu

Trichilemmal differentiation in seborrheic keratosis.

An 88‐year‐old woman who developed a nodule in a lesion of seborrheic keratosis on the frontal scalp was observed. Histopathologically, the nodule was characterized by lobular acanthosis consisting of glycogen rich clear cells and squamoid cells with squamous eddies and melanin blockade melanocytes. Each lobule was covered with an orthokeratotic horny layer which formed wedge‐shaped masses in its central area without formation of an intervening granular layer. The clinical course and histopathological findings suggest that the tumor cells in seborrheic keratosis may tend to a new development of trichilemmal differentiation.

Electron microscopic observations of the so-called granuloma glutaeale infantum

Electron microscopic observation of the so‐called granuloma glutaeale infantum revealed that the granulomatous lesion was composed of neutrophils, lymphocytes, eosinophils, plasma cells, mast cells, histocytes, giant cells, and newly‐formed microvasculatures. The giant cells were classified into three types: in the first type the cells had widely enlarged endoplasmic reticulum: in the second type, the cells phagocytized erythrocytes; in the third type, the cells had vesicles and granules and were similar to histiocytes. Some newly‐formed microvasculatures lacked basal lamina and their lining by endothelial cells was sometimes incomplete.

Subepidermal Calcified Nodule

61才家婦の右上眼瞼に, 約3年前より生じたsubepidermal calcified noduleの1例を報告した。本邦報告例について臨床的に検討し以下の結果をえた。皮疹は通常は単発で, 表面は疣贅様∼顆粒状で, 半球状に隆起し, 色は黄白∼灰白色, 大きさは径1cmまでのものがほとんどである。発生年令は10∼20才台が比較的多く, 発生部位は耳介と眼瞼に好発している。

Infantile Digital Fibromatosis

It is a rare lesion, occurring during the first months of life or at birth, with no evident predilection for sex. It is localized in the second or third phalanx of a finger or toe, on the extensor or lateral aspect. At times more than one finger or toe is involved, or the lesion is bilateral, or it involves both the hand and the foot.