Kiyoshi Negoro

Benign hot bath-related headache.

We describe three cases of women with hot bath‐related headache who reported that their severe paroxysmal headache could be provoked by pouring hot water over themselves or by soaking in a hot bath. In one patient, the headache was also brought on by exposure to cold wind. Another patient had headaches after she dived into a pool and started swimming. Neurological examination, routine laboratory tests, electroencephalography, and brain imaging showed no abnormality in any of the patients. Hot bath‐related headache is a benign headache unassociated with a structural lesion.

A Case of Postprandial Cluster-Like Headache With Prolactinoma: Dramatic Response to Cabergoline

A 17‐year‐old boy without a significant past medical history presented with recurrent cluster‐like headaches induced by meals for 3 years. Magnetic resonance images showed a pituitary tumor. Just after starting treatment with cabergoline, the headaches resolved completely and the patient has been absolutely free from such headache attacks for 2 years.

High-signal basal ganglia on T1-weighted images in a patient with Sydenham's chorea

Abstract We report a 16-year-old girl with Sydenhams chorea. Choreiform movements involved both sides of her body. MRI 2 months after the onset revealed abnormal increased signal on T2-weighted images and enlargement of the caudate and putamen bilaterally. MRI 5 months later showed resolution of the swelling, but with increased signal on T1-weighted images in the putamen, globus pallidus and the head of the caudate nucleus bilaterally, with slightly increased signal intensity on T2-weighted images.

Proton magnetic resonance spectroscopy in corticobasal degeneration and progressive supranuclear palsy

Background:  Corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) each have distinctive clinical features, but diagnosis is often uncertain. Our purpose was to evaluate whether localized, single‐voxel proton magnetic resonance spectroscopy (1H‐MRS) could distinguish between typical CBD and PSP patients.

Study about the Cognitive Characteristic of Length by the Finger Tactile Sense-Measurement on Human Advanced Function of Brain by fMRI

In this study, in order to clarify the human advanced brain information processing mechanism on tactile cognition, we used functional MRI (fMRI) and the manufactured tactile length stimulus presentation equipment by 12 persons normal subjects identified human brain activity region to tactile length cognition without visual guidance. By the experiment result, activation regions are found in the intra-parietal sulcus (IPS), lateral occipital cortex (LOC), dorsal occipital cortex (DOC), MT/V5, Wernicke, Broca, and right dorsolateral prefrontal area. These brain activation regions showed that tactile cognition closely associated with high order vision information processing areas and language information processing areas. On the tactile length cognition, using tactile mental representation, it is accompanied also by logical intellectual judgment at the same time it makes an intuitive cognitional judgment.

Acute myopathy after liver transplantation

To the Editor: We were interested in the article by Campellone et al.1 Liver transplantations were performed in adult patients with liver failure. The authors reported a necrotizing myopathy with loss of myosin thick filaments and a focal accumulation of lipid. They did not mention carnitine despite the fact that the cirrhotic patients showed significant hypocarnitinemia.2 We reported an …

Corticobasal degeneration: MRI and SPECT

We studied seven patients (4 men and 3 women, aged 64–82 years) diagnosed clinically as having corticobasal degeneration. MRI was performed on a 1.5 T MRI unit using a T2-weighted spin echo (SE) sequence (TR 3000, TE 80–90 ms), a T1-weighted SE sequence (TR 550–600, TE 15–20 ms) and a proton density-weighted SE sequence (TR 3000 ms, TE 12–22 ms). Brain perfusion SPECT studies were performed in six patients with 123I-IMP and in one patient with 99mTc-HMPAO. MRI revealed diffuse brain atrophy in six patients and asymmetrical front parietal atrophy, especially in posterior central gyri and superior parietal lobules, in four contralateral to the most affected limbs. SPECT disclosed a decrease in cerebral blood flow in two patients in the thalamus or basal ganglia on the side opposite the affected limbs.

99m Tc-HMPAO single-photon emission tomography in the standing position in cerebral infarction

Consecutive 99mTc-HMPAO studies were performed before and after standing, to the cerebral flow perfusion of the cerebral infarction and normal control. In normal subjects, standing stress decreased the blood flow of the superior frontal, the parietal and the inferior frontal lobes significantly. Standing stress did not decrease the blood flow of the superior frontal lobe and temporal lobe in lacunar infarct patients. The blood flow between standing and supine positions changed significantly around the cerebral infarct in a patient with middle cerebral artery occlusion.

Unilateral asterixis due to a right thalamic hemorrhage.

症例は57歳男性.1990年11月1日, 朝食時めまい感と左上下肢麻痺に気づき, 翌日当科受診.一般内科学的には肥満を認め, 神経学的には意識レベルはJCS1, 頭痛, 構音障害, 左片麻痺, 歩行障害, 左側小脳失調・位置覚低下を認めた.また, 左上肢にasterixisを認めた.受診時の頭部CTにて右視床・右側脳室内に高吸収域を認め, 右視床出血とそれに伴う脳室内穿破と診断された.さらに短潜時体性感覚誘発電位 (SSEP, 正中神経刺激) における中枢神経伝導時間 (CCT) では左刺激での遅延がみられた.Asterixisは代謝性疾患においてしばしばみられるが, 脳血管障害等の器質的疾患にも時に認められる.その発現には錐体路・小脳・後索系の障害と脳幹網様体賦活系の障害が関与している可能性が考えられた.