Kiyotaka Iwai
Dainippon Sumitomo Pharma Co., Ltd.
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Publication
Featured researches published by Kiyotaka Iwai.
Bioorganic & Medicinal Chemistry Letters | 2000
Norio Fujiwara; Hitoshi Fujita; Kiyotaka Iwai; Ayumu Kurimoto; Shinobu Murata; Hajime Kawakami
New piperidylpyrimidine derivatives, including quinazolines, were prepared, and their abilities to inhibit TNF-alpha production evaluated. Some compounds showed potent inhibitory activity in mouse macrophages stimulated with LPS. The synthesis and structure activity relationships of these compounds are described.
Bioorganic & Medicinal Chemistry Letters | 2011
Kantaro Ushiroda; Katsunori Maruta; Makoto Kitoh; Kiyotaka Iwai; Jun Nagamine; Atsushi Tsuchida; Mutsuo Taiji; Ryu Nagata
Starting with a subtle blood glucose-lowering effect of a TGF-β inhibitor, we designed and synthesized a series of benzoylpyrrole-based carboxylic acids as PPARs activators. Among these compounds, 10sNa exhibited favorable blood glucose-lowering effect without body weight gain. We assume that the beneficial effect of 10sNa is attributed to not only its compound PPARα agonistic activity but also its PPARγ partial agonistic activity.
Archive | 2000
Hiroshi Yamaguchi; Katsunori Maruta; Ryu Nagata; Kantaro Ushiroda; Kiyotaka Iwai
Archive | 1999
Hitoshi Fujita; Fujio Antoku; Norio Fujiwara; Kiyotaka Iwai; Hiroshi Tanaka; Hajime Kawakami
Archive | 2003
Katsunori Maruta; Ryu Nagata; Kiyotaka Iwai; Kantaro Ushiroda; Kozo Yoshida
Archive | 1997
Mikio Aoki; Tadahiro Inoue; Kiyotaka Iwai; Hajime Kawakami; Shinji Murata; Shigeyuki Nishinaka; 忠弘 井上; 清高 岩井; 肇 川上; 眞志 村田; 重行 西中; 幹雄 青木
Archive | 2015
Kouichi Amaya; Syuji Iizuka; Kiyotaka Iwai
Archive | 2015
Koichi Amaya; Kiyotaka Iwai; Syuji Iizuka
Archive | 2014
浩一 天谷; Koichi Amaya; 岩井 清高; Kiyotaka Iwai; 清高 岩井; 崇史 飯塚; Takashi Iizuka
Archive | 2003
Katsunori Maruta; Ryu Nagata; Kiyotaka Iwai; Kantaro Ushiroda; Kozo Yoshida
