Knut Conradsen
Technical University of Denmark
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Featured researches published by Knut Conradsen.
IEEE Transactions on Geoscience and Remote Sensing | 2003
Knut Conradsen; Allan Aasbjerg Nielsen; Jesper Schou; Henning Skriver
When working with multilook fully polarimetric synthetic aperture radar (SAR) data, an appropriate way of representing the backscattered signal consists of the so-called covariance matrix. For each pixel, this is a 3/spl times/3 Hermitian positive definite matrix that follows a complex Wishart distribution. Based on this distribution, a test statistic for equality of two such matrices and an associated asymptotic probability for obtaining a smaller value of the test statistic are derived and applied successfully to change detection in polarimetric SAR data. In a case study, EMISAR L-band data from April 17, 1998 and May 20, 1998 covering agricultural fields near Foulum, Denmark are used. Multilook full covariance matrix data, azimuthal symmetric data, covariance matrix diagonal-only data, and horizontal-horizontal (HH), vertical-vertical (VV), or horizontal-vertical (HV) data alone can be used. If applied to HH, VV, or HV data alone, the derived test statistic reduces to the well-known gamma likelihood-ratio test statistic. The derived test statistic and the associated significance value can be applied as a line or edge detector in fully polarimetric SAR data also.
Remote Sensing of Environment | 1998
Allan Aasbjerg Nielsen; Knut Conradsen; James J. Simpson
Abstract This article introduces the multivariate alteration detection (MAD) transformation which is based on the established canonical correlations analysis. It also proposes using postprocessing of the change detected by the MAD variates using maximum autocorrelation factor (MAF) analysis. The MAD and the combined MAF/MAD transformations are invariant to linear scaling. Therefore, they are insensitive, for example, to differences in gain settings in a measuring device, or to linear radiometric and atmospheric correction schemes. Other multivariate change detection schemes described are principal component type analyses of simple difference images. Case studies with AHVRR and Landsat MSS data using simple linear stretching and masking of the change images show the usefulness of the new MAD and MAF/MAD change detection schemes. Ground truth observations confirm the detected changes. A simple simulation of a no-change situation shows the accuracy of the MAD and MAF/MAD transformations compared to principal components based methods.
IEEE Transactions on Geoscience and Remote Sensing | 2003
Jesper Schou; Henning Skriver; Allan Aasbjerg Nielsen; Knut Conradsen
Finding the edges between different regions in an image is one of the fundamental steps of image analysis, and several edge detectors suitable for the special statistics of synthetic aperture radar (SAR) intensity images have previously been developed. In this paper, a new edge detector for polarimetric SAR images is presented using a newly developed test statistic in the complex Wishart distribution to test for equality of covariance matrices. The new edge detector can be applied to a wide range of SAR data from single-channel intensity data to multifrequency and/or multitemporal polarimetric SAR data. By simply changing the parameters characterizing the test statistic according to the applied SAR data, constant false-alarm rate detection is always obtained. An adaptive filtering scheme is presented, and the distributions of the detector are verified using simulated polarimetric SAR images. Using SAR data from the Danish airborne polarimetric SAR, EMISAR, it is demonstrated that superior edge detection results are obtained using polarimetric and/or multifrequency data compared to using only intensity data.
Acta Crystallographica Section A | 1994
N.C. Krieger Lassen; D. Juul Jensen; Knut Conradsen
The statistical analysis of data in the form of orientations is a relatively new discipline and results from the literature on this subject are not yet widely known outside the statistics community. This paper provides an introduction to and the key references for statistical methods for analysing orientation data. More specifically, the problem of estimating an unknown orientation is considered and results on the precision of such an estimated orientation are described. The calculation of average orientation and dispersion parameters for a sample of orientations is also considered. Finally, procedures for generating and testing for random orientations are described. The methodology is illustrated with crystal orientation data obtained from the analysis of electron back-scattering patterns.
Biophysical Journal | 2001
Oleg Aslanidi; O.A. Mornev; Ole Skyggebjerg; Per Arkhammar; Ole Thastrup; Mads Peter Sørensen; P. Christiansen; Knut Conradsen; Alwyn C. Scott
In response to glucose application, beta-cells forming pancreatic islets of Langerhans start bursting oscillations of the membrane potential and intracellular calcium concentration, inducing insulin secretion by the cells. Until recently, it has been assumed that the bursting activity of beta-cells in a single islet of Langerhans is synchronized across the whole islet due to coupling between the cells. However, time delays of several seconds in the activity of distant cells are usually observed in the islets of Langerhans, indicating that electrical/calcium wave propagation through the islets can occur. This work presents both experimental and theoretical evidence for wave propagation in the islets of Langerhans. Experiments with Fura-2 fluorescence monitoring of spatiotemporal calcium dynamics in the islets have clearly shown such wave propagation. Furthermore, numerical simulations of the model describing a cluster of electrically coupled beta-cells have supported our view that the experimentally observed calcium waves are due to electric pulses propagating through the cluster. This point of view is also supported by independent experimental results. Based on the model equations, an approximate analytical expression for the wave velocity is introduced, indicating which parameters can alter the velocity. We point to the possible role of the observed waves as signals controlling the insulin secretion inside the islets of Langerhans, in particular, in the regions that cannot be reached by any external stimuli such as high glucose concentration outside the islets.
IEEE Transactions on Geoscience and Remote Sensing | 1998
Rasmus Larsen; Knut Conradsen; Bjarne Kjær Ersbøll
The estimation of flow fields from time sequences of satellite imagery has a number of important applications. For visualization of cloud or sea ice movements in sequences of crude temporal sampling, a satisfactory nonblurred temporal interpolation can be performed only when the flow field or an estimate thereof is known. Estimated flow fields in weather satellite imagery might also be used on an operational basis as inputs to short-term weather prediction. The authors describe a method for the estimation of dense flow fields. Local measurements of motion are obtained by analysis of the local energy distribution, which is sampled by using a set of three-dimensional (3D) spatio-temporal filters. The estimated local energy distribution also allows the authors to compute a confidence measure of the estimated local normal flow. The algorithm, furthermore, utilizes Markovian random fields in order to integrate the local estimates of normal flows into a dense flow field by using measures of spatial smoothness. To obtain smoothness, the authors will constrain first-order derivatives of the flow field. The performance of the algorithm is illustrated by the estimation of the flow fields corresponding to a sequence of Meteosat thermal images. The estimated flow fields are used in a temporal interpolation scheme.
IEEE Transactions on Signal Processing | 1993
Eyjolfur Gislason; Marnar Johansen; Knut Conradsen; Bjarne Kjær Ersbøll; Søren K. Jacobsen
An error criterion for the design of FIR filters is proposed. Filters with relatively many free filter coefficients are designed using the Chebyshev, the weighted-least-squares (WLS), and a new partitioned minimax error criterion, and the performance of the filters is compared. A general and fast technique for the WLS design is also presented. >
international geoscience and remote sensing symposium | 2001
Knut Conradsen; Allan Aasbjerg Nielsen; Jesper Schou; Henning Skriver
When working with multi-look fully polarimetric synthetic aperture radar (SAR) data an appropriate way of representing the backscattered signal consists of the so-called covariance matrix. For each pixel this is a 3/spl times/3 Hermitian, positive definite matrix which follows a complex Wishart distribution. Based on this distribution a test statistic for equality of two such matrices and an associated asymptotic probability for obtaining a smaller value of the test statistic are given and applied to change detection in polarimetric SAR data. In a case study EMISAR L-band data from 17 April 1998 and 20 May 1998 covering agricultural fields near Foulum, Denmark are used. The derived test statistic can be applied as a line or edge detector in fully polarimetric SAR data also.
Analytical Biochemistry | 1987
I. Søndergaard; Lars K. Poulsen; Martin Hagerup; Knut Conradsen
A computerized method for automatic evaluation and comparison of crossed immunoelectrophoretic and crossed radioimmunoelectrophoretic patterns that requires limited hardware resources has been developed. For the initial reading of the plates an ordinary video camera is used. Feature extractors that allow the computer to recognize a point on the precipitation curve as being a peak point have been developed. After this automatic procedure the program allows for an interactive menu-driven proofreading phase during which it is possible to force the system to take into consideration any number of extra points along the precipitation curve in the curve-fitting process. The system has been tested on crossed immunoelectrophoretic patterns as well as crossed radioimmunoelectrophoretic patterns and it has been shown that the system can recognize the same precipitation curves on different immunoplates and autoradiographs. In addition, the system reports the mean, the variance, and the area of the precipitation curves, thus allowing not only a qualitative comparison of two or more plates but also a quantitation of individual antigens or antibodies.
Advanced Healthcare Materials | 2015
Rasmus Irming Jølck; Jonas Scherman Rydhög; Anders Christensen; Anders Elias Hansen; Linda Maria Bruun; Henrik Schaarup-Jensen; Asger Wenck; Betina Børresen; Annemarie T. Kristensen; Mads Hartvig Clausen; Andreas Kjær; Knut Conradsen; Rasmus Larsen; Per Munck af Rosenschöld; Thomas Lars Andresen
In the western world, approximately 50% of all cancer patients receive radiotherapy alone or in combination with surgery or chemotherapy. Image-guided radiotherapy (IGRT) has in recent years been introduced to enhance precision of the delivery of radiation dose to tumor tissue. Fiducial markers are often inserted inside the tumor to improve IGRT precision and to enable monitoring of the tumor position during radiation therapy. In the present article, a liquid fiducial tissue marker is presented, which can be injected into tumor tissue using thin and flexible needles. The liquid fiducial has high radio-opacity, which allows for marker-based image guidance in 2D and 3D X-ray imaging during radiation therapy. This is achieved by surface-engineering gold nanoparticles to be highly compatible with a carbohydrate-based gelation matrix. The new fiducial marker is investigated in mice where they are highly biocompatible and stable after implantation. To investigate the clinical potential, a study is conducted in a canine cancer patient with spontaneous developed solid tumor in which the marker is successfully injected and used to align and image-guide radiation treatment of the canine patient. It is concluded that the new fiducial marker has highly interesting properties that warrant investigations in cancer patients.