Ko Sawai
Hirosaki University
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Featured researches published by Ko Sawai.
Tetrahedron Letters | 1983
Toshikatsu Okuno; Ikuya Natsume; Ko Sawai; Kenzo Sawamura; Akio Furusaki; Takeshi Matsumoto
Abstract New antifungal hydroxyhydroperylenediones have been isolated from Alternaria sps. and their structures have been shown to be 1 and 2 .
Agricultural and biological chemistry | 1981
Ko Sawai; Toshikatsu Okuno; Yukiyasu Terada; Yukio Harada; Kenzo Sawamura; Hiroshi Sasaki; Shoichi Takao
An antagonistic fungus to Valsa ceratosperma was isolated from soil, and identified as Fusarium solani. The fungus was found to produce at least two antifungal substances in stationary culture. These two substances were isolated from their culture filtrate as chromatographically homogeneous, amorphous solids. Their examined physico-chemical properties appeared to be identical with cyclosporin A and C, obtained from the fermentation broth of Trichoderma polysporum, and they showed a pronounced inhibitory effect on growth of V. ceratosperma.
Agricultural and biological chemistry | 1967
Ko Sawai; Masaoki Koyama; Toshiyasu Maeda; Tokuji Shimomura
The effect of 3-nitropropionate (3-NPA)on oxidative phosphorylation by using mitochondria prepared from both rat liver and brain were investigated in connection with the toxicity of this material. It was found that 3-NPA inhibited oxidative phosphorylation. In this inhibition, the uptake of inorganic phosphate was blocked but the oxygen uptake was not influenced at all. Furthermore, increase in ATPase activity of intact mitochondria was shown by the addition of 3-NPA. Results showed that 3-NPA disturbed oxidative phosphorylation as an uncoupler. However, the degree of inhibition by 3-NPA was not so high in comparison with other well-known uncouplers.Thus the toxicity of 3-NPA is not due to the inhibition of oxidative phosphorylation. 3-NPA also does not affect on cytochrome oxidase activity.
Chemistry Letters | 1974
Toshikatsu Okuno; Yuichi Ishita; Ko Sawai; Takeshi Matsumoto
Agricultural and biological chemistry | 1986
Toshikatsu Okuno; Satoru Oikawa; Takanobu Goto; Ko Sawai; Haruhisa Shirahama; Takeshi Matsumoto
Agricultural and biological chemistry | 1985
Kazuo Miyairi; Toshikatsu Okuno; Ko Sawai
Agricultural and biological chemistry | 1977
Kazuo Miyairi; Koji Fujita; Toshikatsu Okuno; Ko Sawai
Tetrahedron Letters | 1975
Toshikatsu Okuno; Yuichi Ishita; A. Sugawara; Y. Mori; Ko Sawai; Takeshi Matsumoto
Agricultural and biological chemistry | 1981
Ko Sawai; Toshikatsu Okuno; Yukiyasu Terada; Yukio Harada; Kenzo Sawamura; Hiroshi Sasaki; Shoichi Takao
Japanese Journal of Phytopathology | 1982
Ko Sawai; Toshikatsu Okuno; Takako Ito