Kobayashi Shigeru
Takeda Pharmaceutical Company
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Publication
Featured researches published by Kobayashi Shigeru.
Biochemical Pharmacology | 1972
Kokubu Tatsuo; Hiwada Kunio; Yamamura Yuichi; Hayashi Kyozo; Okumura Junko; Hori Masatake; Kobayashi Shigeru; Ueno Hayao
Abstract A renin inhibitor in ox bile was purified by ammonium sulfate fractionation, dialysis and chromatography on Bio-Gel P-2 and Amberiite XAD-2 resin. The inhibitor was shown to be taurodeoxycholic acid by means of nuclear magnetic resonance spectroscopy, gas chromatography, amino acid and elemental analyses. Further confirmation of the assignment was established by the direct comparison of its infrared spectrum with that of an authentic sample. Taurodeoxycholic acid inhibited the reaction of rabbit renin with angiotensinogen in vitro . Glycocholic acid, also present in ox bile, however, had no inhibitory effect on the renin angiotensinogen reaction.
Archive | 1978
Yamamura Yuichi; Azuma Ichiro; Kobayashi Shigeru
Archive | 1973
Fujino Masahiko; Kobayashi Shigeru; Obayashi Mikihiko; Shinagawa Susumu; Fukuda Tsunehiko
Archive | 1973
Fujino Masahiko; Kobayashi Shigeru; Obayashi Mikihiko; Shinagawa Susumu; Fukuda Tsunehiko; Suita Osaka
Archive | 1986
Fujino Masahiko; Kobayashi Shigeru; Obayashi Mikihiko; Shinagawa Susumu; Fukuda Tsunehiko
Archive | 1986
Fujino Mashiko; Kobayashi Shigeru; Obayashi Mikihiko; Shinagawa Susumu; Fukuda Tsunehiko
Archive | 1983
Fujino Masahiko; Kobayashi Shigeru; Obayashi Mikihiko; Shinagawa Susumu; Fukuda Tsunehiko
Archive | 1982
Fukuda Tsunehiko; Kobayashi Shigeru; Fujino Masahiko
Archive | 1980
Fujino Masahiko; Kobayashi Shigeru; Obayashi Mikihiko; Shinagawa Susumu; Fukuda Tsunehiko
Archive | 1979
Fujino Masahiko; Kobayashi Shigeru; Obayashi Mikihiko; Shinagawa Susumu; Fukuda Tsunehiko
