Koichi Kikuchi
Eisai
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Publication
Featured researches published by Koichi Kikuchi.
Journal of Medicinal Chemistry | 2012
Yoshinori Takahashi; Shigeki Hibi; Yorihisa Hoshino; Koichi Kikuchi; Kogyoku Shin; Kaoru Murata-Tai; Masae Fujisawa; Mitsuhiro Ino; Hisashi Shibata; Masahiro Yonaga
Design, synthesis, and structure-activity relationships of a series of 3-dialkylamino-7-phenyl pyrazolo[1,5-a]pyridines (I) as selective antagonists of the corticotropin-releasing factor 1 (CRF(1)) receptor are described. The most prominent compound to emerge from this work, 46 (E2508), exhibits potent in vitro activity, excellent drug-like properties, and robust oral efficacy in animal models of stress-related disorders. It has advanced into clinical trials.
Archive | 1993
Hiroyuki Yoshimura; Mitsuo Nagai; Shigeki Hibi; Koichi Kikuchi; Ieharu Hishinuma; Junichi Nagakawa; Makoto Asada; Norimasa Miyamoto; Takayuki Hida; Aichi Ogasawara; Isao Yamatsu
Archive | 2002
Shigeki Hibi; Koichi Kikuchi; Yorihisa Hoshino; Motohiro Soejima; Tatsuya Yoshiuchi; Kogyoku Shin; Mutsuko Ono; Yoshinori Takahashi; Hisashi Shibata; Mitsuhiro Ino; Tetsuya Hirakawa
Archive | 2002
Shigeki Hibi; Yoshinori Takahashi; Yorihisa Hoshino; Koichi Kikuchi; Motohiro Soejima; Tatsuya Yoshiuchi; Kogyoku Shin; Mutsuko Ono; Hisashi Shibata; Mitsuhiro Ino; Tetsuya Hirakawa
Archive | 1993
Hiroyuki Yoshimura; Mitsuo Nagai; Shigeki Hibi; Koichi Kikuchi; Ieharu Hishinuma; Junichi Nagakawa; Makoto Asada; Norimasa Miyamoto; Takayuki Hida; Aichi Ogasawara; Isao Yamatsu
Archive | 2009
Shigeki Hibi; Yoshinori Takahashi; Yorihisa Hoshino; Koichi Kikuchi; Motohiro Soejima; Tatsuya Yoshiuchi; Kogyoku Shin; Mutsuko Ono; Hisashi Shibata; Mitsuhiro Ino; Tetsuya Hirakawa
Archive | 2003
Shigeki Hibi; Yorihisa Hoshino; Koichi Kikuchi; Kyogyoku Shin; Yoshinori Takahashi; Masae Fujisawa; Hisashi Shibata; Mitsuhiro Ino
Archive | 1996
Shinya Abe; Kiyoko Azuma; Shigeki Hibi; Takayuki Hida; Koichi Kikuchi; Seiichi Kobayashi; Mitsuo Nagai; Makoto Okita; Katsuya Tagami; Naoki Tokuhara; Hiroyuki Yoshimura; 寛幸 吉村; 精一 小林; 直紀 徳原; 滋樹 日比; 聖子 東; 光雄 永井; 真 沖田; 克也 田上; 浩一 菊池; 信也 阿部; 隆之 飛弾
Archive | 2003
Shigeki Hibi; Yorihisa Hoshino; Koichi Kikuchi; Kogyoku Shin; Yoshinori Takahashi; Masae Fujisawa; Hisashi Shibata; Mitsuhiro Ino
Archive | 2009
Yoichi Akutsu; Kunio Araki; Koichi Kikuchi; Shoji Mizoguchi; Shunsaku Nishie; Hidesuke Odera; Masao Saito; Ichiro Seko; Toshio Shinohara; Nagashi Sugiyama; 陽一 圷; 正男 斎藤; 長志 杉山; 昭二 溝口; 一郎 瀬古; 秀介 王寺; 敏雄 篠原; 邦夫 荒木; 浩一 菊池; 俊作 西江
