Kokoro Sano
Keio University
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Featured researches published by Kokoro Sano.
Journal of Medical Internet Research | 2013
Motoko Kawashima; Miki Uchino; Takashi Kawazoe; Masaaki Kamiyashiki; Kokoro Sano; Kazuo Tsubota
Background A Web-based self-check system including a brief questionnaire would seem to be a suitable tool for rapid disease screening. Objective The purpose of this preliminary study was to test a Web-based self-screening questionnaire for drawing attention to dry eye disease among general Internet users and identifying those with a higher risk of developing the condition. Methods A survey website was launched and used to recruit participants from general Internet users. In the first phase, volunteers were asked to complete a Web-based self-screening questionnaire containing 12 questions on dry eye symptoms. The second phase focused on the respondents who reported five or more dry eye symptoms and expressed their intention to seek medical attention. These participants performed the Schirmer test, for evaluating tear production, and completed a paper-based lifestyle questionnaire to provide relevant background data. Results Of the 1689 visitors to the website, 980 (58.0%) volunteers completed the Web-based self-screening questionnaire. Among these, 355 (36.2%) respondents reported five or more dry eye symptoms. Then, 99 (27.9%) of the symptomatic participants performed the Schirmer test and completed the paper-based lifestyle questionnaire. Out of these, 32 (32.2%) had abnormal tear production (≤5 mm). Conclusions The proposed Web-based self-screening questionnaire seems to be a promising tool for raising awareness of dry eye disease among general Internet users and identifying those with a higher risk of developing the condition, although further research is needed to validate its effectiveness.
Ocular Surface | 2015
Kokoro Sano; Motoko Kawashima; Kazuhiro Ikeura; Reiko Arita; Kazuo Tsubota
PURPOSE To determine the relationship between abdominal breathing and tear meniscus volume in healthy women, we investigated the change in tear meniscus volume in two groups: normal breathing and abdominal breathing. METHODS We used a crossover experimental model and examined 20 healthy women aged 20-54 years (mean ± SD, 32.7 ± 11.1 years). The participants were randomly assigned to one of two groups. During the first visit, the normal breathing group was subjected to normal breathing for 3 min, whereas the abdominal breathing group was subjected to abdominal breathing (4-second inhalation and 6-second exhalation) for 3 min. During the second visit, the protocols were swapped between the two groups. We estimated the R wave to R wave (R-R) interval, tear meniscus volume, salivary amylase activity, pulse, and blood pressure before and immediately after, 15 min after, and 30 min after completion of the breathing activity. RESULTS After abdominal breathing, compared to that before breathing, the tear meniscus volume increased significantly 15 min after breathing (P<.01). Furthermore, systolic blood pressure showed a significant decrease immediately after abdominal breathing (P<0.05). No significant difference was found in the test parameters in the normal breathing group. CONCLUSION Abdominal breathing for 3 minutes increases the tear meniscus volume in healthy women. Consequently, abdominal breathing may be considered in the treatment of dry eye disease.
Journal of Occupational Health | 2018
Motoko Kawashima; Kokoro Sano; Sayuri Takechi; Kazuo Tsubota
To evaluate the effects of a 2month lifestyle intervention for dry eye disease in office workers.
Clinical Ophthalmology | 2018
Kokoro Sano; Motoko Kawashima; Sayuri Takechi; Masaru Mimura; Kazuo Tsubota
Introduction We investigated the benefits of a cognitive behavior therapy-based exercise program to reduce the dry eye symptoms of office workers. Materials and methods We recruited 11 office workers with dry eye symptoms, aged 31–64 years, who voluntarily participated in group health guidance at a manufacturing company. Participants learned about the role of physical activity and exercise in enhancing wellness and performed an exercise program at home 3 days per week for 10 weeks. We estimated the indexes of body composition, dry eye symptoms, and psychological distress using the Dry Eye-Related Quality of Life Score and the World Health Organization’s Subjective Well-Being Inventory questionnaires pre- and postintervention. Results The 10-week exercise program and the questionnaires were completed by 48.1% (39 of 81) of the participants. Body composition did not change pre- and postintervention. However, the average of the Dry Eye-Related Quality of Life Score scores in participants with subjective dry eye significantly improved after the intervention. Moreover, the World Health Organization’s Subjective Well-Being Inventory positive well-being score tended to increase after the intervention. Conclusion In this study, we showed that a 10-week exercise program improved subjective dry eye symptoms of healthy office workers. Our study suggests that a cognitive behavior therapy-based exercise program can play an important role in the treatment of patients with dry eye disease.
Investigative Ophthalmology & Visual Science | 2014
Kokoro Sano; Motoko Kawashima; Akiko Ito; Takaaki Inaba; Kohkichi Morimoto; Mitsuhiro Watanabe; Kazuo Tsubota
Investigative Ophthalmology & Visual Science | 2016
Mamoru Kamoshita; Hideto Osada; Eriko Toda; Kokoro Sano; Motoko Kawashima; Norihiro Nagai; Hajime Shinoda; Kazuo Tsubota; Yoko Ozawa
Investigative Ophthalmology & Visual Science | 2016
Kai Jin; Motoko Kawashima; Masataka Ito; Kokoro Sano; Kazuo Tsubota
Investigative Ophthalmology & Visual Science | 2016
Kokoro Sano; Motoko Kawashima; Toshihiro Imada; Ryuji Hisamura; Shigeru Nakamura; Fumiya Izumiseki; Kenji F. Tanaka; Mitsuhiro Watanabe; Masaru Mimura; Kazuo Tsubota
Investigative Ophthalmology & Visual Science | 2015
Kokoro Sano; Motoko Kawashima; Akiko Ito; Imada Toshihiro; Ryuji Hisamura; Shigeru Nakamura; Mitsuhiro Watanabe; Kazuo Tsubota
Investigative Ophthalmology & Visual Science | 2015
Samuel Connell; Motoko Kawashima; Ryuji Hisamura; Kokoro Sano; Akiko Ito; Imada Toshihiro; Kai Jin; Shigeru Nakamura; Kazuo Tsubota