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Dive into the research topics where Konrad Janowski is active.

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Featured researches published by Konrad Janowski.


Archives of Dermatological Research | 2012

Social support and adaptation to the disease in men and women with psoriasis

Konrad Janowski; Stanisława Steuden; Aldona Pietrzak; Dorota Krasowska; Łukasz Kaczmarek; Ilona Gradus; Grażyna Chodorowska

Social support was shown to be an important factor buffering negative effects of stress in a range of clinical populations. Little is known, however, about the role of social support in the population of patients with psoriasis although strong psychosocial stress has been implicated in this disease. The objective of this study was to evaluate the association between social support and selected indices of adaptation to life with the disease, including health-related quality of life, depressive symptoms and acceptance of life with the disease, in a sample of patients with psoriasis. Additionally, gender differences in these relationships were analyzed. One-hundred-four patients with psoriasis completed psychological tests measuring disease-related social support, health-related quality of life, depressive symptoms and acceptance of life with the disease. Psoriasis severity was assessed by Psoriasis Area and Severity Index. The patients reporting higher social support levels had significantly higher quality of life, lower depression levels, and higher acceptance of life with the disease. The strengths of these effects, however, were different in women and men. Higher social support was slightly more closely associated with better acceptance of life with the disease in men than in women. However, higher social support was more closely associated to lower depression and better quality of life in women than in men. Among different types of social support, tangible support was found to be the best predictor for the all adaptation indices. Effects of social support perceived by psoriasis patients on adaptation to the disease may be gender-related and exact pathways of these effects may depend on the type on the dimension of social support and the selected type of adaptation indicator. Tangible support seems the most important type of support contributing to better adaptation in both women and men with psoriasis.


European Spine Journal | 2010

Factors accounting for psychosocial functioning in patients with low back pain

Konrad Janowski; Stanisława Steuden; Joanna Kuryłowicz

Low back pain (LBP) is a chronic disorder which exerts a profound impact on various spheres of psychosocial functioning, including emotional distress, functional limitations and decrements in social contacts. The objective of this study was to investigate the associations between the indices of psychosocial functioning in patients with chronic LBP and a range of psychological factors. Specifically, the study aimed at exploring the relative participation of personality, social support, disease-related cognitive appraisals and coping styles in accounting for the differences in psychosocial functioning of patients with LBP. One-hundred-twenty patients with LBP took part in the study and completed a battery of psychological questionnaires: NEO–Five Factors Inventory, Ways of Coping Questionnaire, Disease-Related Social Support Scale, Disease-Related Appraisals Scale and Psychosocial Functioning Questionnaire (PFQ). The PFQ dimensions were used as dependent variables in a series of stepwise regression analysis models with the scores from other questionnaires entered as independent variables. A cognitive appraisal of the disease in terms of an obstacle was strongly related to all domains of functioning; however, other appraisals (threat, challenge, harm, profit and overall disease importance) were uniquely associated with particular domains of functioning. Deprivation of social support was a significant predictor of distress experienced in interpersonal context and of sense of being disabled. Among basic personality traits, agreeableness was negatively associated with distress in interpersonal context, and conscientiousness was positively related to acceptance of life with the disease. Problem-focus coping was linked to higher acceptance of life with the disease. Among sociodemographic variables, older age and lower educational level were related to greater subjective feelings of being disabled. Pain severity was found unrelated to any of psychosocial functioning domains. Different aspects of psychosocial functioning are best accounted for by diverse patterns of psychological factors, which suggests involvement of different psychological mechanisms in development of LBP-related disability.


International Journal of Dermatology | 2009

Lipoprotein (a) in patients with psoriasis: associations with lipid profiles and disease severity

Aldona Pietrzak; Jacek Kadzielewski; Konrad Janowski; Jacek Roliński; Dorota Krasowska; Grażyna Chodorowska; Tomasz Paszkowski; Ewa Kapec; Iwona Jastrzebska; Jacek Tabarkiewicz; Torello Lotti

Background  Lipoprotein (a) [Lp(a)] is a genetically determined molecule whose role has been implied in cardiovascular pathology, and whose levels have been reported to be elevated in patients with psoriasis.


International Journal of Dermatology | 2014

Clinical and psychological characteristics of patients with psoriasis reporting various frequencies of pruritus

Konrad Janowski; Stanisława Steuden; Jarosław Bogaczewicz

Pruritus is a common subjective symptom of psoriasis whose levels may be affected by a range of variables. The objective of this study was to evaluate the frequency of pruritus and its associations with clinical and psychological characteristics of psoriasis patients.


International Journal of Dermatology | 2008

Psychological stress, endocrine and immune response in patients with lichen planus.

Dorota Krasowska; Aldona Pietrzak; Agata Surdacka; Violetta Tuszyńska‐Bogucka; Konrad Janowski; Jacek Roliński

Background  Lichen planus still remains a disease of unclear etiology. Inconclusive reports exist on the role of stress the pathophysiological mechanisms involved in this disease. The objective of this study was to find associations between levels of stress and indices of the endocrine and immune response in patients with lichen planus.


Dermatologic Therapy | 2008

Indications for psychological intervention in patients with psoriasis.

Konrad Janowski; Aldona Pietrzak

ABSTRACT:  Various forms of psychological interventions have since long been proposed as potentially helpful adjuncts to standard pharmacological therapy of psoriasis. All studies investigating the effectiveness of psychological intervention in psoriasis reported its positive impact on the patients’ psychological well‐being and some studies also reported improvements in the skin condition as a result of psychotherapy. When making a decision about the referral of a given patient to the psychologist, both clinical (psoriasis‐specific) and general (psychotherapy‐specific) indications should be taken into consideration. This can allow a better identification of those psoriasis patients who are in real need for psychological intervention and who are most likely to benefit from it.


Przegla̜d menopauzalny | 2014

Selected determinants of quality of life in women with urinary incontinence

Katarzyna Szymona-Pałkowska; Janusz Kraczkowski; Konrad Janowski; Stanisława Steuden; Jolanta Adamczuk; Jacek Marcin Robak; Szymon Bakalczuk; Grzegorz Bakalczuk

Urinary incontinence (UI) is one of the most common diseases in women. It involves uncontrolled leaking of urine through the urethra. UI incidence depends on age and in certain age groups it can affect up to 60% of the female population. The symptoms can be persistent and due to their embarrassing nature they can lead to significant deterioration of quality of life and psychological functioning. The aim of this study was to investigate the relationship between the quality of life and selected aspects of functioning. Seventy female outpatients of a public clinic in Nałęczów, Poland, were examined, and the following methods were used: the Urinary Incontinence Life Quality Scale (Szymona-Pałkowska, Kraczkowski), Disease-Related Appraisal Scale (Janowski, Steuden), Coping Inventory for Stressful Situations (Endler, Parker), Disease-Related Social Support Scale (Brachowicz, Janowski, Sadowska), and the Knowledge Appraisal Scale for Urinary Incontinence (Szymona-Pałkowska, Kraczkowski). The obtained results suggest that the strongest predictors for the quality of life with UI would be: perception of the disease as an injustice and a challenge (a reverse relationship) and an avoidance-oriented style of coping with stress through companionship seeking (a positive relationship). The duration of the disease and the level of related knowledge proved to be crucial in the analysis of one dimension, i.e. distance to the symptoms.


Postepy Dermatologii I Alergologii | 2014

The Polish version of Skindex-29: psychometric properties of an instrument to measure quality of life in dermatology

Konrad Janowski; Stanisława Steuden; Bernarda Bereza

Introduction Skin conditions have a negative impact on quality of life and it is necessary to quantify this impact. Skindex-29 is a self-report questionnaire developed to measure dermatology-specific quality of life. Aim The objective of this study is to adapt this questionnaire to Polish conditions. The adaptation procedure involved the works on the linguistic content of the items and testing psychometric properties of the Polish version of Skindex-29, including item characteristics, factorial structure, aspects of reliability and validity. Material and methods Two-hundred and ninety patients (63.4% women and 35.2% men) suffering from a range of skin conditions were recruited from several dermatological out-patient and in-patient clinics in Poland. Quality of life was measured using Skindex-29 and appropriate clinical data were collected. Results The global score of Skindex-29 showed the normal distribution. Cronbachs α reliability coefficients were found to be high to very high for all Skindex-29 indexes. Factor analysis yielded four factors, in contrast to the original version of the questionnaire, for which a three-factor solution had been reported. Skindex-29 validity was demonstrated by showing the differences in the quality of life scores across different diagnostic categories, and between in-patients and out-patients. Skindex-29 global scores were found to be significantly predicted by the localization of the skin lesions on legs, anogenital areas and palms. Conclusions The findings of this study support reliability and validity of the Polish version of Skindex-29, but they also raise questions to its three-factor structure.


Mediators of Inflammation | 2007

Plasma Interleukin-18 and Dendritic Cells in Males with Psoriasis Vulgaris

Aldona Pietrzak; Konrad Janowski; Grażyna Chodorowska; Anna Michalak-Stoma; Jacek Roliński; Anna Zalewska; Iwona Jastrzebska; Jacek Tabarkiewicz; Tomasz Paszkowski; Ewa Kapec; Dorota Krasowska

Peripheral blood dendritic cells seem to play a crucial role in psoriatic inflammatory processes. The aim of our study is to investigate the relationship between plasma interleukin-18 (IL-18) levels and blood dendritic cells in psoriatic patients. IL-18 plasma levels were measured by ELISA. Phenotypes of dendritic cell subsets were analyzed by double-colour flow cytometry. Plasma IL-18 level in psoriatic males was significantly higher, whereas counts of BDCA-2+ cells were lower than in the control group. The myeloid/plasmacytoid ratio was significantly higher in the patient group compared to the control one. In the patient group, significant negative correlations between plasma IL-18 level and both the BDCA-1+ and BDCA-2+ counts were found. BDCA-1+ counts correlated negatively with percentage of skin involvement. IL-18 seems to play a role in psoriasis pathogenesis. The decreased counts of blood plasmacytoid DCs in psoriatic patients might result from IL-18 down-regulation of plasmacytoid DC precursor proliferation.


Dermatologic Therapy | 2011

Candida parapsilosis infection following the electrosurgery procedure.

Aldona Pietrzak; Konrad Janowski; Grażyna Chodorowska; Krystyna Trela; Magdalena Szymanek; Dorota Krasowska

Subcutaneous mycoses are fungal infections that predominantly affect the dermis and subcutaneous tissue. The most common pathogen responsible for these infections is Candida albicans; however, another yeast from this group, Candida parapsilosis, becomes the cause of increasing numbers of mycotic infections. Recent reports suggested that this microorganism may be particularly resistant to disinfectants, which can facilitate its spread through the medical staff, instruments, and biomaterial. We report a case of a patient in whom a C. parapsilosis infection occurred as a complication following a minor electrocoagulation procedure. Because all obtained laboratory findings were nonspecific, the infection could be properly diagnosed only through cultures from the skin lesion.

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Aldona Pietrzak

Medical University of Lublin

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Stanisława Steuden

John Paul II Catholic University of Lublin

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Dorota Krasowska

John Paul II Catholic University of Lublin

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Grażyna Chodorowska

Medical University of Lublin

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Małgorzata Tatala

John Paul II Catholic University of Lublin

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Jacek Roliński

John Paul II Catholic University of Lublin

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Ewa Kapec

John Paul II Catholic University of Lublin

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Iwona Jastrzebska

John Paul II Catholic University of Lublin

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Jacek Tabarkiewicz

John Paul II Catholic University of Lublin

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Janusz Kraczkowski

Medical University of Lublin

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